Search Results - "Ojewunmi, Oyesola"

A survey of genetic fetal-haemoglobin modifiers in Nigerian patients with sickle cell anaemia by Adeyemo, Titilope A, Ojewunmi, Oyesola O, Oyetunji, Idat A, Rooks, Helen, Rees, David C, Akinsulie, Adebola O, Akanmu, Alani S, Thein, Swee Lay, Menzel, Stephan

“…Genetic variants at three quantitative trait loci (QTL) for fetal haemoglobin (HbF), BCL11A, HBS1L-MYB and the β-globin gene cluster, have attracted interest…”
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Health related quality of life and perception of stigmatisation in adolescents living with sickle cell disease in Nigeria: A cross sectional study by Adeyemo, Titilope A., Ojewunmi, Oyesola O., Diaku-Akinwumi, Ijeoma N., Ayinde, Oluwaseyi C., Akanmu, Alani S.

“…Background Sickle cell disease impacts the physical, emotional and psychological aspects of life of the affected persons, often times exposing them to disease…”
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The genetic dissection of fetal haemoglobin persistence in sickle cell disease in Nigeria by Ojewunmi, Oyesola O, Adeyemo, Titilope A, Oyetunji, Ajoke I, Inyang, Bassey, Akinrindoye, Afolashade, Mkumbe, Baraka S, Gardner, Kate, Rooks, Helen, Brewin, John, Patel, Hamel, Lee, Sang Hyuck, Chung, Raymond, Rashkin, Sara, Kang, Guolian, Chianumba, Reuben, Sangeda, Raphael, Mwita, Liberata, Isa, Hezekiah, Agumadu, Uche-Nnebe, Ekong, Rosemary, Faruk, Jamilu A, Jamoh, Bello Y, Adebiyi, Niyi M, Umar, Ismail A, Hassan, Abdulaziz, Grace, Christopher, Goel, Anuj, Inusa, Baba P D, Falchi, Mario, Nkya, Siana, Makani, Julie, Ahmad, Hafsat R, Nnodu, Obiageli, Strouboulis, John, Menzel, Stephan

“…Abstract The clinical severity of sickle cell disease (SCD) is strongly influenced by the level of fetal haemoglobin (HbF) persistent in each patient. Three…”
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Accounting for heterogeneity due to environmental sources in meta-analysis of genome-wide association studies by Wang, Siru, Ojewunmi, Oyesola O., Kamiza, Abram, Ramsay, Michele, Morris, Andrew P., Chikowore, Tinashe, Fatumo, Segun, Asimit, Jennifer L.

“…Meta-analysis of genome-wide association studies (GWAS) across diverse populations offers power gains to identify loci associated with complex traits and…”
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Current perspectives of sickle cell disease in Nigeria: changing the narratives by Ojewunmi, Oyesola O, Adeyemo, Titilope A, Ayinde, Oluseyi C, Iwalokun, Bamidele, Adekile, Adekunle

“…: Sickle cell disease (SCD) is an inherited blood disorder characterized by clinical heterogeneity that may be influenced by environmental factors, ethnicity,…”
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Barriers to the use of hydroxyurea in the management of sickle cell disease in Nigeria by Adeyemo, Titilope A., Diaku-Akinwunmi, Ijeoma N., Ojewunmi, Oyesola O., Bolarinwa, Abiola B., Adekile, Adekunle D.

“…Hydroxyurea (HU) is a well-known Hb F-inducing agent with proven clinical and laboratory efficacy for patients with sickle cell disease. However, concerns…”
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Fetal-haemoglobin enhancing genotype at BCL11A reduces HbA 2 levels in patients with sickle cell anaemia by Adeyemo, Titilope A, Ojewunmi, Oyesola O, Oyetunji, Idayat Ajoke, Kalejaiye, Olufunto Olufela, Menzel, Stephan

“…Understanding the interplay of genetic factors with haemoglobin expression and pathological processes in sickle cell disease is important for pharmacological…”
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Fetal‐haemoglobin enhancing genotype at BCL11A reduces HbA2 levels in patients with sickle cell anaemia by Adeyemo, Titilope A., Ojewunmi, Oyesola O., Oyetunji, Idayat Ajoke, Kalejaiye, Olufunto Olufela, Menzel, Stephan

“…Understanding the interplay of genetic factors with haemoglobin expression and pathological processes in sickle cell disease is important for pharmacological…”
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Prevalence, Determinants and Impact of Haemoglobin Phenotype Misdiagnosis Among Parents of Children Living with Sickle Cell Disease in Nigeria by Adekunle, Motunrayo Oluwabukola, Ojewunmi, Oyesola, Animasahun, Adeola Barakat, Lawani, Faith Ozavisa, Ubuane, Peter Odion

“…Aim: Nigeria has the highest number of children with sickle cell disease (SCD) with a consistent prevalence of 2 to 3% despite increased awareness and…”
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Impact of training of mothers, drug shop attendants and voluntary health workers on effective diagnosis and treatment of malaria in Lagos, Nigeria by Ajibaye, Olusola, Balogun, Emmanuel, Olukosi, Yetunde, Orok, Bassey, Oyebola, Kolapo, Iwalokun, Bamidele, Aina, Olugbenga, Shittu, Olalere, Adeneye, Adeniyi, Oyesola Ojewunmi, Kita, K, Samson Awolola

“…Background: The National Malaria Eradication Program and international agencies are keen on scaling up the use of malaria rapid diagnostic tests (mRDTs) and…”
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Contribution of single-nucleotide polymorphism in transcription factor 7-like 2 gene to cardiometabolic risk in adult Nigerians by Udenze, Ifeoma, Taiwo, Idowu, Ojewunmi, Oyesola

“…Background: Single-nucleotide polymorphism in the gene, transcription factor 7-like 2 (TCF7L2), shows the strongest and most consistent association with risk…”
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Association of alpha‐thalassemia and Glucose‐6‐Phosphate Dehydrogenase deficiency with transcranial Doppler ultrasonography in Nigerian children with sickle cell anemia by Ojewunmi, Oyesola Oyewole, Adeyemo, Titilope Adenike, Oyetunji, Ajoke Idayat, Benn, Yewande, Ekpo, Mfoniso Godwin, Iwalokun, Bamidele Abiodun

“…Background Stroke is a devastating complication of sickle cell anemia (SCA) and can be predicted through abnormally high cerebral blood flow velocity using…”
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Serum concentrations of IL-16 and its genetic polymorphism rs4778889 affect the susceptibility and severity of endometriosis in Nigerian women by Babah, Ochuwa Adiketu, Ojewunmi, Oyesola Oyewole, Onwuamah, Chika Kingsley, Udenze, Ifeoma Christiana, Osuntoki, Akinniyi Adediran, Afolabi, Bosede Bukola

“…Endometriosis is the presence of active ectopic endometrial glands and stroma at other sites outside the uterine cavity. It is a common cause of chronic pelvic…”
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Genetic Polymorphisms of Glucose-6-Phosphate Dehydrogenase in Lagos, Nigeria by Babalola, Musa O., Imaga, Ngozi A., Samuel, Titilola A., Diriwari, Iyanu P., Kolade, Olajumoke, Ezeamalu, Irene, Laoye, Adefioye O., Ojewunmi, Oyesola O.

“…Glucose-6-phosphate dehydrogenase (G6PD) is an essential enzyme in the pentose phosphate pathway that prevents oxidative damage to cells. This study determined…”
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Genetic polymorphisms of Vascular Endothelial Growth Factor (VEGF) associated with endometriosis in Nigerian women by Babah, Ochuwa Adiketu, Ojewunmi, Oyesola Oyewole, Osuntoki, Akinniyi Adediran, Simon, Melissa A, Afolabi, Bosede Bukola

“…To determine if genetic polymorphism of VEGF is associated with the development of endometriosis in Nigerian women. Case control study of 100 women (50 healthy…”
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Haemoglobin oxygen saturation, leucocyte count and lactate dehydrogenase are predictors of elevated cerebral blood flow velocity in Nigerian children with sickle cell anaemia by Ojewunmi, Oyesola Oyewole, Adeyemo, Titilope Adenike, Osuntoki, Akinniyi Adediran, Imaga, Ngozi Awa, Oyetunji, Ajoke Idayat

“…Background: Transcranial Doppler ultrasound (TCD) scan, which measures blood flow velocity through the time-averaged mean of maximum velocities (TAMMVs) in the…”
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Capacity building and stroke risk assessment in Nigerian children with sickle cell anaemia by Soyebi, Kofo, Adeyemo, Titilope, Ojewunmi, Oyesola, James, Funmi, Adefalujo, Kunle, Akinyanju, Olu

“…Background Transcranial Doppler ultrasonography (TCD) measures blood flow velocities in the large cerebral vessels and thus, detects the risk of stroke. This…”
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The COPILOT Raw Illumina Genotyping QC Protocol by Patel, Hamel, Lee, Sang-Hyuck, Breen, Gerome, Menzel, Stephen, Ojewunmi, Oyesola, Dobson, Richard J B

“…The Illumina genotyping microarrays generate data in image format, which is processed by the platform-specific software GenomeStudio, followed by an array of…”
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Evaluation of high performance liquid chromatography (HPLC) pattern and prevalence of beta-thalassaemia trait among sickle cell disease patients in Lagos, Nigeria by Adeyemo, Titilope, Ojewunmi, Oyesola, Oyetunji, Ajoke

“…Sickle cell disease (SCD) is the most common inherited disorder of haemoglobin worldwide. This study evaluated the chromatographic patterns and red blood cell…”
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Asymptomatic malaria infection among children with Sickle Cell Anaemia: The role of IL-10 and possible predisposing factors by Oyetunji, Idayat Ajoke, Amoo, Abimbola Joseph, Adeyemo, Titilope Adenike, Ojewunmi, Oyesola Oyewole

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