Search Results - "Oikonomou, Evangelos K."

The role of adipose tissue in cardiovascular health and disease by Oikonomou, Evangelos K., Antoniades, Charalambos

“…Accumulating knowledge on the biology and function of the adipose tissue has led to a major shift in our understanding of its role in health and disease. The…”
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Perivascular adipose tissue and coronary atherosclerosis by Mancio, Jennifer, Oikonomou, Evangelos K, Antoniades, Charalambos

“…Adipose tissue (AT) is no longer viewed as a passive, energy-storing depot, and a growing body of evidence supports the concept that both quantitative and…”
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Machine learning in precision diabetes care and cardiovascular risk prediction by Oikonomou, Evangelos K, Khera, Rohan

“…Artificial intelligence and machine learning are driving a paradigm shift in medicine, promising data-driven, personalized solutions for managing diabetes and…”
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Non-invasive detection of coronary inflammation using computed tomography and prediction of residual cardiovascular risk (the CRISP CT study): a post-hoc analysis of prospective outcome data by Oikonomou, Evangelos K, Marwan, Mohamed, Desai, Milind Y, Mancio, Jennifer, Alashi, Alaa, Hutt Centeno, Erika, Thomas, Sheena, Herdman, Laura, Kotanidis, Christos P, Thomas, Katharine E, Griffin, Brian P, Flamm, Scott D, Antonopoulos, Alexios S, Shirodaria, Cheerag, Sabharwal, Nikant, Deanfield, John, Neubauer, Stefan, Hopewell, Jemma C, Channon, Keith M, Achenbach, Stephan, Antoniades, Charalambos

“…Coronary artery inflammation inhibits adipogenesis in adjacent perivascular fat. A novel imaging biomarker—the perivascular fat attenuation index…”
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A novel machine learning-derived radiotranscriptomic signature of perivascular fat improves cardiac risk prediction using coronary CT angiography by Oikonomou, Evangelos K, Williams, Michelle C, Kotanidis, Christos P, Desai, Milind Y, Marwan, Mohamed, Antonopoulos, Alexios S, Thomas, Katharine E, Thomas, Sheena, Akoumianakis, Ioannis, Fan, Lampson M, Kesavan, Sujatha, Herdman, Laura, Alashi, Alaa, Centeno, Erika Hutt, Lyasheva, Maria, Griffin, Brian P, Flamm, Scott D, Shirodaria, Cheerag, Sabharwal, Nikant, Kelion, Andrew, Dweck, Marc R, Van Beek, Edwin J R, Deanfield, John, Hopewell, Jemma C, Neubauer, Stefan, Channon, Keith M, Achenbach, Stephan, Newby, David E, Antoniades, Charalambos

“…Abstract Background Coronary inflammation induces dynamic changes in the balance between water and lipid content in perivascular adipose tissue (PVAT), as…”
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Detecting human coronary inflammation by imaging perivascular fat by Antonopoulos, Alexios S, Sanna, Fabio, Sabharwal, Nikant, Thomas, Sheena, Oikonomou, Evangelos K, Herdman, Laura, Margaritis, Marios, Shirodaria, Cheerag, Kampoli, Anna-Maria, Akoumianakis, Ioannis, Petrou, Mario, Sayeed, Rana, Krasopoulos, George, Psarros, Constantinos, Ciccone, Patricia, Brophy, Carl M, Digby, Janet, Kelion, Andrew, Uberoi, Raman, Anthony, Suzan, Alexopoulos, Nikolaos, Tousoulis, Dimitris, Achenbach, Stephan, Neubauer, Stefan, Channon, Keith M, Antoniades, Charalambos

“…Early detection of vascular inflammation would allow deployment of targeted strategies for the prevention or treatment of multiple disease states. Because…”
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Immunometabolic Regulation of Vascular Redox State: The Role of Adipose Tissue by Oikonomou, Evangelos K, Antoniades, Charalambos

“…Vascular oxidative stress plays a crucial role in atherogenesis and cardiovascular disease (CVD). Recent evidence suggests that vascular redox state is under…”
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Adipose tissue-derived WNT5A regulates vascular redox signaling in obesity via USP17/RAC1-mediated activation of NADPH oxidases by Akoumianakis, Ioannis, Sanna, Fabio, Margaritis, Marios, Badi, Ileana, Akawi, Nadia, Herdman, Laura, Coutinho, Patricia, Fagan, Harry, Antonopoulos, Alexios S, Oikonomou, Evangelos K, Thomas, Sheena, Chiu, Amy P, Chuaiphichai, Surawee, Kotanidis, Christos P, Christodoulides, Constantinos, Petrou, Mario, Krasopoulos, George, Sayeed, Rana, Lv, Lei, Hale, Ashley, Naeimi Kararoudi, Meisam, McNeill, Eileen, Douglas, Gillian, George, Sarah, Tousoulis, Dimitris, Channon, Keith M, Antoniades, Charalambos

“…Obesity is associated with changes in the secretome of adipose tissue (AT), which affects the vasculature through endocrine and paracrine mechanisms…”
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Assessing Cardiovascular Risk by Using the Fat Attenuation Index in Coronary CT Angiography by Klüner, Laura V, Oikonomou, Evangelos K, Antoniades, Charalambos

“…Coronary CT angiography (CCTA) has evolved into a first-line diagnostic test for the investigation of chest pain. Despite advances toward standardizing the…”
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A prospective study of external stenting of saphenous vein grafts to the right coronary artery: the VEST II study by Taggart, David P, Amin, Sanaz, Djordjevic, Jasmina, Oikonomou, Evangelos K, Thomas, Sheena, Kampoli, Anna-Maria, Sabharwal, Nikant, Antoniades, Charalambos, Krasopoulos, George

“…Abstract OBJECTIVES: External stents significantly reduce intimal hyperplasia and improve lumen uniformity and flow pattern in saphenous vein grafts (SVG) 1…”
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Detection of left ventricular systolic dysfunction from single-lead electrocardiography adapted for portable and wearable devices by Khunte, Akshay, Sangha, Veer, Oikonomou, Evangelos K., Dhingra, Lovedeep S., Aminorroaya, Arya, Mortazavi, Bobak J., Coppi, Andreas, Brandt, Cynthia A., Krumholz, Harlan M., Khera, Rohan

“…Artificial intelligence (AI) can detect left ventricular systolic dysfunction (LVSD) from electrocardiograms (ECGs). Wearable devices could allow for broad…”
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Artificial intelligence in cardiovascular imaging—principles, expectations, and limitations by Antoniades, Charalambos, Oikonomou, Evangelos K

“…Graphical Abstract Graphical Abstract Seven lessons for cardiologists in the era of artificial intelligence. When reviewing an artificial intelligence…”
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Efficient deep learning-based automated diagnosis from echocardiography with contrastive self-supervised learning by Holste, Gregory, Oikonomou, Evangelos K., Mortazavi, Bobak J., Wang, Zhangyang, Khera, Rohan

“…Background Advances in self-supervised learning (SSL) have enabled state-of-the-art automated medical image diagnosis from small, labeled datasets. This label…”
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Multimodality Advanced Cardiovascular and Molecular Imaging for Early Detection and Monitoring of Cancer Therapy-Associated Cardiotoxicity and the Role of Artificial Intelligence and Big Data by Kwan, Jennifer M, Oikonomou, Evangelos K, Henry, Mariana L, Sinusas, Albert J

“…Cancer mortality has improved due to earlier detection screening, as well as due to novel cancer therapies such as tyrosine kinase inhibitors and immune…”
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An explainable machine learning-based phenomapping strategy for adaptive predictive enrichment in randomized clinical trials by Oikonomou, Evangelos K., Thangaraj, Phyllis M., Bhatt, Deepak L., Ross, Joseph S., Young, Lawrence H., Krumholz, Harlan M., Suchard, Marc A., Khera, Rohan

“…Randomized clinical trials (RCT) represent the cornerstone of evidence-based medicine but are resource-intensive. We propose and evaluate a machine learning…”
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Artificial intelligence in medical imaging: A radiomic guide to precision phenotyping of cardiovascular disease by Oikonomou, Evangelos K, Siddique, Musib, Antoniades, Charalambos

“…Abstract Rapid technological advances in non-invasive imaging, coupled with the availability of large data sets and the expansion of computational models and…”
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Non-steroidal treatment of cardiac sarcoidosis: A systematic review by Gallegos, Cesia, Oikonomou, Evangelos K., Grimshaw, Alyssa, Gulati, Mridu, Young, Bryan D., Miller, Edward J.

“…The treatment of active cardiac sarcoidosis (CS) usually involves immunosuppressive therapy, with the goal of preventing inflammation-induced scar formation…”
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Video-Based Kinematic Analysis of Movement Quality in a Phase 3 Clinical Trial of Troriluzole in Adults with Spinocerebellar Ataxia: A Post Hoc Analysis by L’Italien, Gilbert J., Oikonomou, Evangelos K., Khera, Rohan, Potashman, Michele H., Beiner, Melissa W., Maclaine, Grant D. H., Schmahmann, Jeremy D., Perlman, Susan, Coric, Vladimir

“…Introduction Traditional methods for assessing movement quality rely on subjective standardized scales and clinical expertise. This limitation creates…”
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Artificial intelligence-enhanced patient evaluation: bridging art and science by Oikonomou, Evangelos K, Khera, Rohan

“…Graphical Abstract Graphical Abstract Bridging the art of traditional clinical evaluation with data-driven insights from new artificial intelligence-enabled…”
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The effect of in-hospital acquired thrombocytopenia on the outcome of patients with acute coronary syndromes: A systematic review and meta-analysis by Oikonomou, Evangelos K., MD, Repanas, Theodoros I., MD, Papanastasiou, Christos, MD, Kokkinidis, Damianos G., MD, Miligkos, Michael, MD MS, Feher, Attila, MD PhD, Gupta, Dipti, MD MPH, Kampaktsis, Polydoros N., MD

“…Abstract Background In-hospital acquired thrombocytopenia (TP) is relatively common among patients hospitalized with acute coronary syndromes (ACS). However,…”
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