Search Results - "Oieni, Jacopo"

Extracellular Matrix Hydrogels Originated from Different Organs Mediate Tissue-Specific Properties and Function by Davidov, Tzila, Efraim, Yael, Hayam, Rotem, Oieni, Jacopo, Baruch, Limor, Machluf, Marcelle

“…Porcine extracellular matrix (pECM)-derived hydrogels were introduced, in recent years, aiming to benefit the pECM's microstructure and bioactivity, while…”
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Hydrogel-based delivery of antimiR-221 enhances cartilage regeneration by endogenous cells by Lolli, Andrea, Sivasubramaniyan, Kavitha, Vainieri, Maria L., Oieni, Jacopo, Kops, Nicole, Yayon, Avner, van Osch, Gerjo J.V.M.

“…Articular cartilage is frequently injured by trauma or osteoarthritis, with limited and inadequate treatment options. We investigated a new strategy based on…”
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Nano-ghosts: Novel biomimetic nano-vesicles for the delivery of antisense oligonucleotides by Oieni, Jacopo, Lolli, Andrea, D'Atri, Domenico, Kops, Nicole, Yayon, Avner, van Osch, Gerjo J.V.M., Machluf, Marcelle

“…Antisense oligonucleotides (ASOs) carry an enormous therapeutic potential in different research areas, however, the lack of appropriate carriers for their…”
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Drug delivery in intervertebral disc degeneration and osteoarthritis: Selecting the optimal platform for the delivery of disease-modifying agents by Colella, Fabio, Garcia, João Pedro, Sorbona, Marco, Lolli, Andrea, Antunes, Bernardo, D'Atri, Domenico, Barré, Florian P.Y., Oieni, Jacopo, Vainieri, Maria Letizia, Zerrillo, Luana, Capar, Serdar, Häckel, Sonja, Cai, Yunpeng, Creemers, Laura B.

“…Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) as major cause of chronic low back pain represent the most common degenerative joint…”
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Nano-Ghosts: Biomimetic membranal vesicles, technology and characterization by Oieni, Jacopo, Levy, Lior, Letko Khait, Nitzan, Yosef, Liat, Schoen, Beth, Fliman, Miguel, Shalom-Luxenburg, Hagit, Malkah Dayan, Natali, D'Atri, Domenico, Cohen Anavy, Noa, Machluf, Marcelle

“…•Investigation of Nano-Ghosts manufacturing-process robustness.•Examination of post-production shelf-life through stability and storage studies.•Demonstration…”
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DHEA modulates the effect of cortisol on RACK1 expression via interference with the splicing of the glucocorticoid receptor by Pinto, Antonella, Malacrida, Beatrice, Oieni, Jacopo, Serafini, Melania Maria, Davin, Annalisa, Galbiati, Valentina, Corsini, Emanuela, Racchi, Marco

“…Background and Purpose Dehydroepiandrosterone (DHEA) is thought to be an anti‐glucocorticoid hormone known to be fully functional in young people but deficient…”
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Control of backbone chemistry and chirality boost oligonucleotide splice switching activity by Kandasamy, Pachamuthu, McClorey, Graham, Shimizu, Mamoru, Kothari, Nayantara, Alam, Rowshon, Iwamoto, Naoki, Kumarasamy, Jayakanthan, Bommineni, Gopal R, Bezigian, Adam, Chivatakarn, Onanong, Butler, David C D, Byrne, Michael, Chwalenia, Katarzyna, Davies, Kay E, Desai, Jigar, Shelke, Juili Dilip, Durbin, Ann F, Ellerington, Ruth, Edwards, Ben, Godfrey, Jack, Hoss, Andrew, Liu, Fangjun, Longo, Kenneth, Lu, Genliang, Marappan, Subramanian, Oieni, Jacopo, Paik, Ik-Hyeon, Estabrook, Erin Purcell, Shivalila, Chikdu, Tischbein, Maeve, Kawamoto, Tomomi, Rinaldi, Carlo, Rajão-Saraiva, Joana, Tripathi, Snehlata, Yang, Hailin, Yin, Yuan, Zhao, Xiansi, Zhou, Cong, Zhang, Jason, Apponi, Luciano, Wood, Matthew J A, Vargeese, Chandra

“…Abstract Although recent regulatory approval of splice-switching oligonucleotides (SSOs) for the treatment of neuromuscular disease such as Duchenne muscular…”
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Exon skipping induces uniform dystrophin rescue with dose-dependent restoration of serum miRNA biomarkers and muscle biophysical properties by Chwalenia, Katarzyna, Oieni, Jacopo, Zemła, Joanna, Lekka, Małgorzata, Ahlskog, Nina, Coenen-Stass, Anna M.L., McClorey, Graham, Wood, Matthew J.A., Lomonosova, Yulia, Roberts, Thomas C.

“…Therapies that restore dystrophin expression are presumed to correct Duchenne muscular dystrophy (DMD), with antisense-mediated exon skipping being the leading…”
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Pretreating Mesenchymal Stem Cells with Cancer Conditioned‐Media or Proinflammatory Cytokines Changes the Tumor and Immune Targeting by Nanoghosts Derived from these Cells by Lupu‐Haber, Yael, Bronshtein, Tomer, Shalom‐Luxenburg, Hagit, D'Atri, Domenico, Oieni, Jacopo, Kaneti, Limor, Shagan, Alona, Hamias, Shani, Amram, Liat, Kaneti, Galoz, Cohen Anavy, Noa, Machluf, Marcelle

“…Nanoghosts (NGs) are nanovesicles reconstructed from the cytoplasmic membranes of mesenchymal stem cells (MSCs). By retaining MSC membranes, the NGs retain the…”
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