Search Results - "Ohyama, Tatsuya"

Nearest-neighbor parameters for predicting DNA duplex stability in diverse molecular crowding conditions by Ghosh, Saptarshi, Takahashi, Shuntaro, Ohyama, Tatsuya, Endoh, Tamaki, Tateishi-Karimata, Hisae, Sugimoto, Naoki

“…The intracellular environment is crowded and heterogeneous. Although the thermodynamic stability of nucleic acid duplexes is predictable in dilute solutions,…”
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Volumetric Strategy for Quantitatively Elucidating a Local Hydration Network around a G‑Quadruplex by Matsumoto, Saki, Takahashi, Shuntaro, Bhowmik, Sudipta, Ohyama, Tatsuya, Sugimoto, Naoki

“…Hydration around nucleic acids, such as DNA and RNA, is an important factor not only for the stability of nucleic acids but also for their interaction with…”
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Theranostic approach to specifically targeting the interloop region of BCL2 i-motif DNA by crystal violet by Das, Sinjan, Takahashi, Shuntaro, Ohyama, Tatsuya, Bhowmik, Sudipta, Sugimoto, Naoki

“…Ligands that recognise specific i-motif DNAs are helpful in cancer diagnostics and therapeutics, as i-motif formation can cause cancer. Although the loop…”
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RNA‐Capturing Microsphere Particles (R‐CAMPs) for Optimization of Functional Aptamers by Endoh, Tamaki, Ohyama, Tatsuya, Sugimoto, Naoki

“…RNA aptamers are useful building blocks for constructing functional nucleic acid‐based nanoarchitectures. The abilities of aptamers to recognize specific…”
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Improved nearest-neighbor parameters for the stability of RNA/DNA hybrids under a physiological condition by Banerjee, Dipanwita, Tateishi-Karimata, Hisae, Ohyama, Tatsuya, Ghosh, Saptarshi, Endoh, Tamaki, Takahashi, Shuntaro, Sugimoto, Naoki

“…Abstract The stability of Watson–Crick paired RNA/DNA hybrids is important for designing optimal oligonucleotides for ASO (Antisense Oligonucleotide) and…”
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Effect of DNA modifications on the transition between canonical and non-canonical DNA structures in CpG islands during senescence by Matsumoto, Saki, Tateishi-Karimata, Hisae, Ohyama, Tatsuya, Sugimoto, Naoki

“…Patterns and levels of DNA modifications play important roles in senescence. Two major epigenetic modifications of DNA, 5-methylcytosine (5mC) and…”
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Nearest-neighbor parameters for the prediction of RNA duplex stability in diverse in vitro and cellular-like crowding conditions by Ghosh, Saptarshi, Takahashi, Shuntaro, Banerjee, Dipanwita, Ohyama, Tatsuya, Endoh, Tamaki, Tateishi-Karimata, Hisae, Sugimoto, Naoki

“…Abstract RNA performs various spatiotemporal functions in living cells. As the solution environments significantly affect the stability of RNA duplexes, a…”
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Effect of Potassium Concentration on Triplex Stability under Molecular Crowding Conditions by Teng, Ye, Tateishi-Karimata, Hisae, Ohyama, Tatsuya, Sugimoto, Naoki

“…The properties of non-canonical DNA structures, like G-quadruplexes and triplexes, change under cell-mimicking molecular crowding conditions relative to dilute…”
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Intramolecular G-quadruplex-hairpin loop structure competition of a GC-rich exon region in the TMPRSS2 gene by Sugimoto, Wataru, Kinoshita, Natsuki, Nakata, Minori, Ohyama, Tatsuya, Tateishi-Karimata, Hisae, Nishikata, Takahito, Sugimoto, Naoki, Miyoshi, Daisuke, Kawauchi, Keiko

“…We identified cytosine-rich regions adjacent to guanine-rich regions in protease genes. A typical GC-rich sequence derived from the gene showed structural…”
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Correction to ‘Improved nearest-neighbor parameters for the stability of RNA/DNA hybrids under a physiological condition’ by Banerjee, Dipanwita, Tateishi-Karimata, Hisae, Ohyama, Tatsuya, Ghosh, Saptarshi, Endoh, Tamaki, Takahashi, Shuntaro, Sugimoto, Naoki

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Special Features of COVID-19 in the FMODB: Fragment Molecular Orbital Calculations and Interaction Energy Analysis of SARS-CoV-2-Related Proteins by Fukuzawa, Kaori, Kato, Koichiro, Watanabe, Chiduru, Kawashima, Yusuke, Handa, Yuma, Yamamoto, Ami, Watanabe, Kazuki, Ohyama, Tatsuya, Kamisaka, Kikuko, Takaya, Daisuke, Honma, Teruki

“…SARS-CoV-2 is the causative agent of coronavirus (known as COVID-19), the virus causing the current pandemic. There are ongoing research studies to develop…”
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New Modified Deoxythymine with Dibranched Tetraethylene Glycol Stabilizes G-Quadruplex Structures by Tateishi-Karimata, Hisae, Ohyama, Tatsuya, Muraoka, Takahiro, Tanaka, Shigenori, Kinbara, Kazushi, Sugimoto, Naoki

“…Methods for stabilizing G-quadruplex formation is a promising therapeutic approach for cancer treatment and other biomedical applications because stable…”
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Interactions between Prefrontal Cortex and Cerebellum Revealed by Trace Eyelid Conditioning by Kalmbach, Brian E, Ohyama, Tatsuya, Kreider, Joy C, Riusech, Frank, Mauk, Michael D

“…Eyelid conditioning has proven useful for analysis of learning and computation in the cerebellum. Two variants, delay and trace conditioning, differ only by…”
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Learning-Induced Plasticity in Deep Cerebellar Nucleus by Ohyama, Tatsuya, Nores, William L, Medina, Javier F, Riusech, Frank A, Mauk, Michael D

“…Evidence that cerebellar learning involves more than one site of plasticity comes from, in part, pavlovian eyelid conditioning, where disconnecting the…”
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Drastic stability change of X-X mismatch in d(CXG) trinucleotide repeat disorders under molecular crowding condition by Teng, Ye, Pramanik, Smritimoy, Tateishi-Karimata, Hisae, Ohyama, Tatsuya, Sugimoto, Naoki

“…The trinucleotide repeat d(CXG) (X = A, C, G or T) is the most common sequence causing repeat expansion disorders. The formation of non-canonical structures,…”
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MK-0626,a selective DPP-4 inhibitor,attenuates hepatic steatosis in ob/ob mice by Ohyama, Tatsuya, Sato, Ken, Yamazaki, Yuichi, Hashizume, Hiroaki, Horiguchi, Norio, Kakizaki, Satoru, Mori, Masatomo, Kusano, Motoyasu, Yamada, Masanobu

“…AIM:To investigate the mechanism and in vivo effects of MK-0626,a dipeptidyl peptidase-4 inhibitor,on hepatic steatosis using ob/ob mice.METHODS:We analyzed…”
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Temporal patterns of inputs to cerebellum necessary and sufficient for trace eyelid conditioning by Kalmbach, Brian E, Ohyama, Tatsuya, Mauk, Michael D

“…Trace eyelid conditioning is a form of associative learning that requires several forebrain structures and cerebellum. Previous work suggests that at least two…”
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Clinical and virological features of acute hepatitis E in Gunma prefecture, Japan between 2004 and 2015 by Yamazaki, Yuichi, Naganuma, Atsushi, Arai, Yosuke, Takeuchi, Suguru, Kobayashi, Takeshi, Takakusagi, Satoshi, Hatanaka, Takeshi, Hoshino, Takashi, Namikawa, Masashi, Hashizume, Hiroaki, Takizawa, Daichi, Ohyama, Tatsuya, Suzuki, Hideyuki, Horiguchi, Norio, Takagi, Hitoshi, Sato, Ken, Kakizaki, Satoru, Kusano, Motoyasu, Nagashima, Shigeo, Takahashi, Masaharu, Okamoto, Hiroaki, Yamada, Masanobu

“…Aim To evaluate the clinical and virological features of acute hepatitis E (AH‐E) in Gunma prefecture and focus on the hepatitis E virus (HEV) infection in…”
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Cerebellar cortex contributions to the expression and timing of conditioned eyelid responses by Kalmbach, Brian E, Davis, Tobin, Ohyama, Tatsuya, Riusech, Frank, Nores, William L, Mauk, Michael D

“…We used micro-infusions during eyelid conditioning in rabbits to investigate the relative contributions of cerebellar cortex and the underlying deep nuclei…”
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An Autopsy Case of Fulminant Hepatitis in a Patient with Multiple Sclerosis Treated by Interferon-Beta-1a by Yamazaki, Yuichi, Suzuki, Aya, Hirayanagi, Kimitoshi, Tsukagoshi, Yusuke, Uehara, Ryota, Horiguchi, Kazuhiko, Ohyama, Tatsuya, Tomaru, Takuya, Horiguchi, Norio, Nobusawa, Sumihito, Ikota, Hayato, Sato, Ken, Kakizaki, Satoru, Kusano, Motoyasu, Ikeda, Yoshio, Yokoo, Hideaki, Yamada, Masanobu

“…A 44-year-old woman with multiple sclerosis (MS) receiving interferon (IFN)-beta-1a treatment was admitted to a local hospital for severe icterus and liver…”
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