Search Results - "Ohyama, Kazumi"

Organoids with cancer stem cell-like properties secrete exosomes and HSP90 in a 3D nanoenvironment by Eguchi, Takanori, Sogawa, Chiharu, Okusha, Yuka, Uchibe, Kenta, Iinuma, Ryosuke, Ono, Kisho, Nakano, Keisuke, Murakami, Jun, Itoh, Manabu, Arai, Kazuya, Fujiwara, Toshifumi, Namba, Yuri, Murata, Yoshiki, Ohyama, Kazumi, Shimomura, Manami, Okamura, Hirohiko, Takigawa, Masaharu, Nakatsura, Tetsuya, Kozaki, Ken-Ichi, Okamoto, Kuniaki, Calderwood, Stuart K

“…Ability to form cellular aggregations such as tumorspheres and spheroids have been used as a morphological marker of malignant cancer cells and in particular…”
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Gel-Free 3D Tumoroids with Stem Cell Properties Modeling Drug Resistance to Cisplatin and Imatinib in Metastatic Colorectal Cancer by Sogawa, Chiharu, Eguchi, Takanori, Namba, Yuri, Okusha, Yuka, Aoyama, Eriko, Ohyama, Kazumi, Okamoto, Kuniaki

“…Researchers have developed several three-dimensional (3D) culture systems, including spheroids, organoids, and tumoroids with increased properties of cancer…”
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Depletion of Lipid Efflux Pump ABCG1 Triggers the Intracellular Accumulation of Extracellular Vesicles and Reduces Aggregation and Tumorigenesis of Metastatic Cancer Cells by Namba, Yuri, Sogawa, Chiharu, Okusha, Yuka, Kawai, Hotaka, Itagaki, Mami, Ono, Kisho, Murakami, Jun, Aoyama, Eriko, Ohyama, Kazumi, Asaumi, Jun-Ichi, Takigawa, Masaharu, Okamoto, Kuniaki, Calderwood, Stuart K, Kozaki, Ken-Ichi, Eguchi, Takanori

“…The ATP-binding cassette transporter G1 (ABCG1) is a cholesterol lipid efflux pump whose role in tumor growth has been largely unknown. Our transcriptomics…”
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Protective effect of cepharanthin on cisplatin-induced renal toxicity through metallothionein expression by Sogawa, Norio, Hirai, Kanji, Sogawa, Chiharu, Ohyama, Kazumi, Miyazaki, Ikuko, Tsukamoto, Goichi, Asanuma, Masato, Sasaki, Akira, Kitayama, Shigeo

“…Cisplatin (CDDP) is a potent anticancer agent, but severe renal toxicity can limit its use. We investigated the protective effect of cepharanthin (CE), a…”
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Antiallodynic Action of 1-(3-(9H-Carbazol-9-yl)-1-propyl)-4-(2-methyoxyphenyl)-4-piperidinol (NNC05-2090), a Betaine/GABA Transporter Inhibitor by Jinzenji, Ayako, Sogawa, Chiharu, Miyawaki, Takuya, Wen, Xue-fang, Yi, Dan, Ohyama, Kazumi, Kitayama, Shigeo, Sogawa, Norio, Morita, Katsuya

“…The GABAergic system in the spinal cord has been shown to participate in neuropathic pain in various animal models. GABA transporters (GATs) play a role in…”
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Methylone and Monoamine Transporters: Correlation with Toxicity by Sogawa, Chiharu, Sogawa, Norio, Ohyama, Kazumi, Kikura-Hanajiri, Ruri, Goda, Yukihiro, Sora, Ichiro, Kitayama, Shigeo

“…Methylone (2-methylamino-1-[3,4-methylenedioxyphenyl]propane-1-one) is a synthetic hallucinogenic amphetamine analog, like MDMA (3,4-methylenedioxy-…”
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Expression and function of variants of human catecholamine transporters lacking the fifth transmembrane region encoded by exon 6 by Sogawa, Chiharu, Mitsuhata, Chieko, Kumagai-Morioka, Kei, Sogawa, Norio, Ohyama, Kazumi, Morita, Katsuya, Kozai, Katsuyuki, Dohi, Toshihiro, Kitayama, Shigeo

“…The transporters for dopamine (DAT) and norepinephrine (NET) are members of the Na+- and Cl--dependent neurotransmitter transporter family SLC6. There is a…”
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Age-dependent changes in the susceptibility to thiopental anesthesia in mice: Analysis of the relationship to the functional expression of GABA transporter by Sogawa, Norio, Hazehara, Yuri, Kunitomo, Muneyoshi, Morita, Yuya, Yoo, Bupsang, Ohyama, Kazumi, Sogawa, Chiharu, Kitayama, Shigeo

“…The potency of anesthetics changes during development, probably due not only to pharmacokinetic factors such as differential distribution and/or metabolism,…”
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Inhibitory action of antidepressants on mouse Betaine/GABA transporter (BGT1) heterologously expressed in cell cultures by Gerile, Sogawa, Chiharu, Ohyama, Kazumi, Masuko, Takashi, Kusama, Tadashi, Morita, Katsuya, Sogawa, Norio, Kitayama, Shigeo

“…Betaine/γ-aminobutyric acid (GABA) transporter (BGT1, SLC6A12) is a member of the Na(+)- and Cl(-)-dependent neurotransmitter transporter gene family with a…”
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Effect of connective tissue growth factor (CCN2/CTGF) on proliferation and differentiation of mouse periodontal ligament-derived cells by Asano, Masahiro, Kubota, Satoshi, Nakanishi, Tohru, Nishida, Takashi, Yamaai, Tomoichiro, Yosimichi, Gen, Ohyama, Kazumi, Sugimoto, Tomosada, Murayama, Yoji, Takigawa, Masaharu

“…CCN2/CTGF is known to be involved in tooth germ development and periodontal tissue remodeling, as well as in mesenchymal tissue development and regeneration…”
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Gene expression of connective tissue growth factor (CTGF/CCN2) in calcifying tissues of normal and cbfa1-null mutant mice in late stage of embryonic development by YAMAAI, Tomoichiro, NAKANISHI, Tohm, ASANO, Masahiro, NAWACHI, Kumiko, YOSHIMICHI, Gen, OHYAMA, Kaziimi, KOMORI, Toshifumi, SUGIMOTO, Tomosada, TAKIGAWA, Masaharu

“…Connective tissue growth factor (CTGF/CCN2), one of the most recently described growth factors, is produced by chondrocytes, vascular endothelial cells, and…”
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Interaction of AP-1 and the ctgf gene: a possible driver of chondrocyte hypertrophy in growth cartilage by MORITAN, Norifumi H, KUBOTA, Satoshi, EGUCHI, Takanori, FUKUNAGA, Tomohiro, YAMASHIRO, Takashi, TAKANO-YAMAMOTO, Teruko, TAHARA, Hideki, OHYAMA, Kazumi, SUGAHARA, Toshio, TAKIGAWA, Masaharu

“…The expression of the connective tissue growth factor ( ctgf) gene increases along with the differentiation of growth cartilage cells, and the highest…”
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Antiallodynic Action of 1-(3-(9H-Carbazol-9-yl)-1-propyl)-4-(2-methyoxyphenyl)-4-piperidin o l (NNC05-2090), a Betaine/GABA Transporter Inhibitor by Jinzenji, Ayako, Sogawa, Chiharu, Miyawaki, Takuya, Wen, Xue-Fang, Yi, Dan, Ohyama, Kazumi, Kitayama, Shigeo, Sogawa, Norio, Morita, Katsuya

“…The GABAergic system in the spinal cord has been shown to participate in neuropathic pain in various animal models. GABA transporters (GATs) play a role in…”
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Developmental changes in susceptibility to thiopental anesthesia in mice treated with GABA uptake inhibitors by Sogawa, Chiharu, Sogawa, Norio, Ohyama, Kazumi, Ge, Rile, Hirai, Kanji, Kitayama, Shigeo

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Neurotrophin-3 increases the DNA-binding activities of several transcription factors in a mouse osteoblastic cell line by Iwata, Emi, Nakanishi, Tohru, Ogawa, Norio, Ohyama, Kazumi, Murakami, Takako, Takigawa, Masaharu

“…In the mouse osteoblastic cell line MC3T3-E1, the signaling responses of several DNA-binding proteins induced by the treatment of neurotrophin-3 were examined…”
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Expression of trkC in a mouse osteoblastic cell line and its response to neurotrophin-3 by Nakanishi, T, Ohyama, K, Aoki, C, Kudo, A, Hattori, T, Takahashi, K, Taniguchi, S, Takigawa, M

“…In a cultured osteoblastic cell line, MC3T3-E1 derived from newborn mouse calvaria, the mRNA encoding TRKC, which is the receptor molecule of neurotrophin-3…”
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