Search Results - "Ohtsu, Hironori"

Synthesis of dl-standishinal and its related compounds for the studies on structure–activity relationship of inhibitory activity against aromatase by Katoh, Takahiro, Akagi, Taichi, Noguchi, Chie, Kajimoto, Tetsuya, Node, Manabu, Tanaka, Reiko, Nishizawa (née Iwamoto), Manabu, Ohtsu, Hironori, Suzuki, Noriyuki, Saito, Koichi

“…dl-Standishinal ( 1), an aromatase inhibitor isolated from Thuja standishii, was synthesized in 15 steps from p-formylanisole via aldol reaction of…”
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Potential Antitumor-Promoting Diterpenoids from the Stem Bark of Picea glehni by KINOUCHI, Yoshitaka, OHTSU, Hironori, TOKUDA, Harukuni, NISHINO, Hoyoku, MATSUNAGA, Shunyo, TANAKA, Reiko

“…A novel rearranged labdane-type diterpenoid, 19(4-->3)abeo-8alpha, 13(S)-epoxylabda-4(18),14-diene (1), and two new abietane-type diterpenoids,…”
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Aromatase inhibitory activities of standishinal and the diterpenoids from the bark of Thuja standishii by Minami, Toshifumi, Iwamoto, Manabu, Ohtsu, Hironori, Ohishi, Hirofumi, Tanaka, Reiko, Yoshitake, Akira

“…The absolute stereostructure of a novel skeletal diterpene, standishinal (1), from the bark of Thuja standishii was confirmed by X-ray crystallographic…”
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Potential antitumor promoting diterpenoids from the stem bark of Thuja standishii by Iwamoto, Manabu, Minami, Toshifumi, Tokuda, Harukuni, Ohtsu, Hironori, Tanaka, Reiko

“…Six diterpenes, including one new natural product, were isolated from a CHCl 3 extract of the stem bark of Thuja standishii. The new compound has been…”
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Standishinal, a novel carbon skeletal diterpene from the bark of Thuja standishii (Gord.) Carr by Ohtsu, Hironori, Iwamoto, Manabu, Ohishi, Hirofumi, Matsunaga, Shunyo, Tanaka, Reiko

“…Standishinal ( 1), a new irregular abietane-type diterpenoid, was isolated from the bark of Thuja standishii and the absolute stereostructure was established…”
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Antitumor agents 222. † †For Part 221, see ref 1. Synthesis and anti-androgen activity of new diarylheptanoids by Ohtsu, Hironori, Itokawa, Hideji, Xiao, Zhiyan, Su, Ching-Yuan, Shih, Charles C.-Y, Chiang, Tzuying, Chang, Eugene, Lee, YiFen, Chiu, Shang-Yi, Chang, Chawnshang, Lee, Kuo-Hsiung

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Abietane Diterpenoids from the Cones of Larix kaempferi by Ohtsu, Hironori, Tanaka, Reiko, Matsunaga, Shunyo

“…Three new abietane-type diterpenes, 7α,15-dihydroxyabieta-8,11,13-trien-18-al (1); 15,18-dihydroxyabieta-8,11,13-trien-7-one (2); and…”
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Antitumor Agents. 217. † Curcumin Analogues as Novel Androgen Receptor Antagonists with Potential as Anti-Prostate Cancer Agents by OHTSU, Hironori, XIAO, Zhiyan, ISHIDA, Junko, NAGAI, Masahiro, WANG, Hui-Kang, ITOKAWA, Hideji, SU, Ching-Yuan, SHIH, Charles, CHIANG, Tzuying, CHANG, Eugene, LEE, Yifen, TSAI, Meng-Yin, CHANG, Chawnshang, LEE, Kuo-Hsiung

“…A number of curcumin analogues were prepared and evaluated as potential androgen receptor antagonists against two human prostate cancer cell lines, PC-3 and…”
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Antitumor Agents. Part 214: Synthesis and Evaluation of Curcumin Analogues as Cytotoxic Agents by Ishida, Junko, Ohtsu, Hironori, Tachibana, Yoko, Nakanishi, Yuka, Bastow, Kenneth F, Nagai, Masahiro, Wang, Hui-Kang, Itokawa, Hideji, Lee, Kuo-Hsiung

“…Fifty-eight curcumin analogues were prepared and evaluated for in vitro cytotoxicity against a panel of human tumor cell lines. Compound 50 was the most potent…”
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Labdane-Type Diterpenes and a Nordrimane-Type Sesquiterpene from the Stem Bark of Thuja standishii by Iwamoto, Manabu, Ohtsu, Hironori, Matsunaga, Shunyo, Tanaka, Reiko

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Corrigendum to “Anti-tumor promoting diterpenes from the stem bark of Thuja standishii (Cupressaceae)” [Bioorg. Med. Chem. 9 (2001) 1911–1921] by Iwamoto, Manabu, Ohtsu, Hironori, Tokuda, Harukuni, Nishino, Hoyoku, Matsunaga, Shunyo, Tanaka, Reiko

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Abietane diterpene acids and other constituents from the leaves of Larix kaempferi by Tanaka, Reiko, Ohtsu, Hironori, Matsunaga, Shunyo

“…Three new dehydroabietane diterpene acids ( 13, 14, 15) were isolated from the leaves of Larix kaempferi as their corresponding methyl esters ( 13a–15a)…”
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Antitumor agents 222. Synthesis and anti-androgen activity of new diarylheptanoids by OHTSU, Hironori, ITOKAWA, Hideji, LEE, Kuo-Hsiung, XIAO, Zhiyan, SU, Ching-Yuan, SHIN, Charles C.-Y, CHIANG, Tzuying, CHANGE, Eugene, LEE, Yifen, CHIU, Shang-Yi, CHANGE, Chawnshang

“…Fifteen new diarylheptanoids were synthesized and evaluated for antagonistic activity against androgen receptor (AR)-mediated reporter gene transcription using…”
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Antitumor agents 216. Synthesis and evaluation of paclitaxel–camptothecin conjugates as novel cytotoxic agents by Ohtsu, Hironori, Nakanishi, Yuka, Bastow, Kenneth F, Lee, Fang-Yu, Lee, Kuo-Hsiung

“…Five conjugates ( 16– 20) composed of a paclitaxel and a camptothecin derivative joined by an imine linkage were synthesized and evaluated as cytotoxic agents…”
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Anti-tumor Promoting Diterpenes from the Stem Bark of Thuja standishii (Cupressaceae) by Iwamoto, Manabu, Ohtsu, Hironori, Tokuda, Harukuni, Nishino, Hoyoku, Matsunaga, Shunyo, Tanaka, Reiko

“…Three new labdane-type diterpenoids, labda-8(17),13-dien-15,12 R-olid-19-oic acid ( 1), 12 S-hydroxylabda-8(17),13(16),14-trien-19-oic acid ( 2) and…”
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Oral Administration of (11E)-13-Oxo-15,16-dinorlabda-8(20),11-dien-19-oic Acid Strongly Reduces Photocarcinogenesis in Mouse Skin Exposed to UV-B Irradiation by Nishizawa, Manabu, Ohtsu, Hironori, Tanaka, Reiko, Tokuda, Harukuni, Katoh, Takahiro, Takeo, Masatoshi, Node, Manabu

“…(11E)‐13‐Oxo‐15,16‐dinorlabda‐8(20),11‐dien‐19‐oic Acid (1), obtained either from the stem bark of Thuja standishii or readily prepared in larger quantities…”
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Cancer chemopreventive agents, labdane diterpenoids from the stem bark of Thuja standishii (Gord.) Carr by TANAKA, Reiko, OHTSU, Hironori, IWAMOTO, Manabu, MINAMI, Toshifumi, TOKUDA, Harukuni, NISHINO, Hoyoku, MATSUNAGA, Shunyo, YOSHITAKE, Akira

“…Seven labdane-type diterpenoids from the stem bark of Thuja standishii (Gord.) Carr. (Cupressaceae) and their analogues showed strong inhibitory effects on…”
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Antitumor agents 216. Synthesis and evaluation of paclitaxel–camptothecin conjugates as novel cytotoxic agents1 by Ohtsu, Hironori, Nakanishi, Yuka, Bastow, Kenneth F, Lee, Fang-Yu, Lee, Kuo-Hsiung

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Tetracyclic triterpenes and other constituents from the leaves and bark of Larix kaempferi by Ohtsu, Hironori, Tanaka, Reiko, Michida, Takashi, Shingu, Tetsuro, Matsunaga, Shunyo

“…Two new triterpenes were isolated from the leaves of Larix kaempferi together with two known compounds, 24-methylenecycloartanone and 24-methylenecycloartanol…”
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Abietane diterpenoids from the cones of Larix kaempferi and their inhibitory effects on Epstein-Barr virus activation by Ohtsu, H, Tanak, R, In, Y, Matsunaga, S, Tokuda, H, Nishino, H

“…Four known (1-3, 8) and four new abietane diterpenes, 15-hydroxy-8alpha,14alpha,12alpha,13alpha-diepoxyabietan-18-oic acid (4),…”
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