Search Results - "Ohtake, Keiko"
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c‐Ki‐rasPoint Mutations in Ductectatic‐type Mucinous Cystic Neoplasms of the Pancreas
Published in Japanese Journal of Cancer Research (01-10-1991)“…Ductectatic‐type mutinous cystic neoplasms of the pancreas constitute a recently recognized new human pancreatic tumor entity. Examination for the presence of…”
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2
Frequent loss of heterozygosity on chromosome 4 in diethylnitrosamine-induced C3H/MSM mouse hepatocellular carcinomas in culture
Published in Molecular carcinogenesis (01-05-1995)“…Genetic changes, in particular the loss of heterozygosity (LOH) and the presence of c-Ha-ras codon 61 point mutations, were investigated in…”
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3
Frequent c-Ki-ras oncogene activation in mucous cell hyperplasias of pancreas suffering from chronic inflammation
Published in Cancer research (Chicago, Ill.) (01-03-1993)“…In order to scrutinize the possible significance of (nonatypical) mucous cell hyperplasia of the pancreas to neoplasia, we analyzed these lesions in terms of…”
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4
Clonal growth of hepatitis B virus-integrated hepatocytes in cirrhotic liver nodules
Published in Cancer research (Chicago, Ill.) (15-12-1992)“…A total of 83 cirrhotic nodules (pseudolobules) individually collected from 11 cirrhotic livers of hepatitis B virus carrier patient were analyzed for the…”
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5
Rearrangement of Integrated HBV DNA in Descendants of Transgenic Mice
Published in Proceedings of the Japan Academy, Series B (1986)Get full text
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6
Hepatocyte growth factor transforms immortalized mouse liver epithelial cells
Published in Oncogene (01-11-1993)“…Transforming activity of hepatocyte growth factor (HGF) was demonstrated utilizing immortalized but not fully transformed mouse hepatocytes (MLE-10). Rat HGF…”
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7
Hepatocarcinogenesis in Transgenic Mice Carrying Albumin‐promoted SV40 T Antigen Gene
Published in Japanese Journal of Cancer Research (01-11-1991)“…We have developed transgenic mice that inherit albumin promoter‐regulated simian virus 40 (SV40) large T antigen gene, expressed specifically in hepatocytes…”
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Subcutaneous Sarcomas of Probable Neuronal Origin in a Transgenic Mouse Strain Containing an Albumin Promoter‐fused Simian Virus 40 Large T Antigen Gene
Published in Japanese Journal of Cancer Research (01-06-1994)“…Frequent development of subcutaneous neurogenic sarcomas was observed in a hepatocellular carcinoma‐producing transgenic mouse strain harboring an…”
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9
Malignant transformation of a mouse liver epithelial cell line by transfection of an activated c-H-ras gene with a point mutation at codon 12
Published in Carcinogenesis (New York) (01-05-1993)“…In order to scrutinize the reason why in mouse liver system only activated H-ras gene with a point mutation at codon 61 but not codon 12 is frequently seen…”
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10
Detection of activated c-H-ras oncogene in hepatocellular carcinomas developing in transgenic mice harboring albumin promoter-regulated simian virus 40 gene
Published in Carcinogenesis (New York) (01-07-1990)“…Hepatocellular carcinomas (HCCs) developing in transgenic mice harboring an albumin promoter-regulated simian virus 40 (SV40) tumor antigen gene were analyzed…”
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11
Absence of H-ras point mutation at codon 12 inN-methyl-N-nitrosourea-induced hepatocellular neoplasms in the rat
Published in Journal of cancer research and clinical oncology (01-07-1990)Get full text
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12
Frequent spontaneous sister chromatid exchange in hepatocytes of transgenic mice harboring the SV40-T antigen gene
Published in Journal of cancer research and clinical oncology (01-08-1992)“…In order to shed light on the causal mechanisms of hepatocarcinogenesis in the transgenic mouse into which the albumin-promotor-regulated SV40-T antigen gene…”
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13
In vitro Progression‐associated c‐H‐ras Activation in Neoplastic Hepatocyte Lines Established from SV40‐T Antigen Gene‐harboring Transgenic Mice
Published in Japanese Journal of Cancer Research (01-01-1991)“…In order to investigate the molecular mechanisms of multistep hepatocarcinogenesis in SV40‐T antigen gene‐harboring transgenic mice, 9 hepatocellular carcinoma…”
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14
Absence of H-ras point mutation of codon 12 in N-methyl-N-nitrosourea-induced hepatocellular neoplasms in the rat
Published in Journal of cancer research and clinical oncology (01-01-1990)“…In order to assess the possibility that activated ras-associated hepatic carcinomas might be much rarer in rats than mice because of the more frequent or rapid…”
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15
c-Ki-ras point mutations in ductectatic-type mucinous cystic neoplasms of the pancreas
Published in Japanese journal of cancer research (Gann) (01-10-1991)“…Ductectatic-type mucinous cystic neoplasms of the pancreas constitute a recently recognized new human pancreatic tumor entity. Examination for the presence of…”
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16
Development of transgenic mice containing woodchuck hepatitis virus DNA
Published in Gastroenterologia Japonica (01-09-1990)“…We produced transgenic mice containing woodchuck hepatitis virus DNA with tandem repeat structure capable of producing virus and viral antigens. Poly(A)+ RNAs…”
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17
Instability of integrated hepatitis B virus DNA with inverted repeat structure in a transgenic mouse
Published in Cancer genetics and cytogenetics (01-02-1989)“…We established four cell lines, from the liver cells of a transgenic mouse, constructed with hepatitis B virus DNA that had an inverted repeat structure. The…”
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