Search Results - "Ohta, Tomihisa"
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Isolation of Antipodal (−)-Versicolamide B and Notoamides L−N from a Marine-Derived Aspergillus sp
Published in Organic letters (19-03-2009)“…Antipodal (−)-versicolamide B and notoamides L−N were isolated from a marine-derived Aspergillus sp. The possible biosynthetic pathway of enantiomeric pairs of…”
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Bioactive phenylpropanoid glycosides from Tabebuia avellanedae
Published in Molecules (Basel, Switzerland) (24-06-2013)“…Three novel phenylpropanoid glycosides 2, 5, 6 were isolated from water extract of Tabebuia avellanedae, together with three known phenylpropanoid glycosides…”
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Isolation and identification of novel selective antitumor constituents, sidrin and sidroside, from Zizyphus spina-christi
Published in Saudi pharmaceutical journal (01-06-2023)“…The leaves of Zizyphus spina-christi (L.) Willd contain several compounds exhibiting different pharmacologic activities. However, studies on the cytotoxic…”
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Isolation of Notoamide E, a Key Precursor in the Biosynthesis of Prenylated Indole Alkaloids in a Marine-Derived Fungus, Aspergillus sp
Published in Journal of the American Chemical Society (25-03-2009)“…Notoamide E was identified to be a short-lived precursor in the biosynthesis of prenylated indole alkaloids in the mussel-derived Aspergillus sp. In addition,…”
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Anti-inflammatory and Anti-melanogenic Proanthocyanidin Oligomers from Peanut Skin
Published in Biological & pharmaceutical bulletin (2012)“…Peanut skin (Arachis hypogaea L., Fabaceae) is an abundant source for polyphenols, such as proanthocyanidin oligomers. To determine whether proanthocyanidin…”
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CYP3A4 Inhibitors Isolated from Licorice
Published in Biological & Pharmaceutical Bulletin (01-10-2005)“…The extract of licorice (Glycyrrhiza uralensis FISHER, Leguminosae) showed CYP3A4 inhibitory activity with the IC50 value of 0.022 mg/ml. Bioassay-guided…”
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Role of Furanocoumarin Derivatives on Grapefruit Juice-Mediated Inhibition of Human CYP3A Activity
Published in Drug metabolism and disposition (01-07-2000)“…With juices of grapefruit and related fruits, possible relationships between contents of six different furanocoumarins and extents of inhibition of microsomal…”
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Leucettamol A: A new inhibitor of Ubc13-Uev1A interaction isolated from a marine sponge, Leucetta aff. microrhaphis
Published in Bioorganic & medicinal chemistry (15-12-2008)“…Leucettamol A is the first inhibitor of Ubc13-Uev1A interaction. Such inhibitors are presumed to be leads for anti-cancer agents that upregulate activity of…”
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Inhibition Selectivity of Grapefruit Juice Components on Human Cytochromes P450
Published in Archives of biochemistry and biophysics (15-06-2000)“…Five compounds including furanocoumarin monomers (bergamottin, 6′,7′-dihydroxybergamottin (DHB)), furanocoumarin dimers…”
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Hexylitaconic acid: A new inhibitor of p53–HDM2 interaction isolated from a marine-derived fungus, Arthrinium sp
Published in Bioorganic & medicinal chemistry letters (2006)“…(−)-Hexylitaconic acid ( 1), a new inhibitor of p53–HDM2 interaction, was isolated from a culture of marine-derived fungus, Arthrinium sp. Compound 1 is the…”
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Capsicum ethanol extracts and capsaicin enhance interleukin-2 and interferon-gamma production in cultured murine Peyer's patch cells ex vivo
Published in Life sciences (1973) (03-04-2007)“…We investigated the effects of red pepper ( Capsicum annuum Lin.) extracts (capsicum extract) and its main pungent capsaicin on T helper 1 (Th1) and 2 (Th2)…”
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Aqueous Extract of Peanut Skin and Its Main Constituent Procyanidin A1 Suppress Serum IgE and IgG1 Levels in Mice-Immunized with Ovalbumin
Published in Biological & pharmaceutical bulletin (01-05-2007)“…In this study, we investigated the effects of an aqueous extract of peanut (Arachis hypogaea L.) seed skin (PSE) and its main constituent procyanidin A1 (PA)…”
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Cytotoxic Fatty Acid from Pleurocybella porrigens
Published in Chemical & Pharmaceutical Bulletin (01-12-2007)“…The new conjugated ketonic fatty acid, porrigenic acid (1), was isolated as a cytotoxic constituent of Pleurocybella porrigens. The structure of 1 was…”
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Garlic extract and its selected organosulphur constituents promote ileal immune responses ex vivo
Published in Journal of functional foods (01-01-2012)“…The effects of garlic extract and three organosulphur compounds of garlic on intestinal immune responses in mice were investigated. Peyer’s patch (PP) cells…”
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Himeic acid A: a new ubiquitin-activating enzyme inhibitor isolated from a marine-derived fungus, Aspergillus sp
Published in Bioorganic & medicinal chemistry letters (03-01-2005)“…[Display omitted] A new ubiquitin-activating enzyme (E1) inhibitor, himeic acid A, was isolated from a culture of marine-derived fungus, Aspergillus sp. The…”
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Isolation of CYP3A4 Inhibitors from the Black Cohosh (Cimicifuga racemosa)
Published in Evidence-based complementary and alternative medicine (01-06-2005)“…Recent investigation on drug interaction has shown that some foods and herbal medicines increase the oral availability of a variety of CYP3A4 substrates, which…”
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Monodictyquinone A: a New Antimicrobial Anthraquinone from a Sea Urchin-Derived Fungus Monodictys sp
Published in Chemical & pharmaceutical bulletin (01-01-2007)“…A new antimicrobial anthraquinone, 1,8-dihydroxy-2-methoxy-6-methylanthraquinone, monodictyquinone A (1), was isolated from a culture of a marine-derived…”
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Isolation of Cytochrome P450 Inhibitors from Strawberry Fruit, Fragaria ananassa
Published in Journal of natural products (Washington, D.C.) (01-11-2004)“…A new glycoside, 2-β-d-glucopyranosyloxy-4,6-dihydroxyisovalerophenone (3), was isolated from strawberry fruit along with…”
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Secomycalolide A: A New Proteasome Inhibitor Isolated from a Marine Sponge of the Genus Mycale
Published in Marine drugs (01-06-2005)“…A new oxazole-containing proteasome inhibitor, secomycalolide A, together with known mycalolide A and 30-hydroxymycalolide A, was isolated from a marine sponge…”
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