Search Results - "Ohta, Tomihisa"

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  1. 1

    Isolation of Antipodal (−)-Versicolamide B and Notoamides L−N from a Marine-Derived Aspergillus sp by Tsukamoto, Sachiko, Kawabata, Tetsuro, Kato, Hikaru, Greshock, Thomas J, Hirota, Hiroshi, Ohta, Tomihisa, Williams, Robert M

    Published in Organic letters (19-03-2009)
    “…Antipodal (−)-versicolamide B and notoamides L−N were isolated from a marine-derived Aspergillus sp. The possible biosynthetic pathway of enantiomeric pairs of…”
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  2. 2

    Bioactive phenylpropanoid glycosides from Tabebuia avellanedae by Suo, Maorong, Ohta, Tomihisa, Takano, Fumihide, Jin, Shouwen

    Published in Molecules (Basel, Switzerland) (24-06-2013)
    “…Three novel phenylpropanoid glycosides 2, 5, 6 were isolated from water extract of Tabebuia avellanedae, together with three known phenylpropanoid glycosides…”
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  3. 3

    Isolation and identification of novel selective antitumor constituents, sidrin and sidroside, from Zizyphus spina-christi by Mostafa, Mahmoud A.H., Khojah, Hani M.J., Ohta, Tomihisa

    Published in Saudi pharmaceutical journal (01-06-2023)
    “…The leaves of Zizyphus spina-christi (L.) Willd contain several compounds exhibiting different pharmacologic activities. However, studies on the cytotoxic…”
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  4. 4

    Isolation of Notoamide E, a Key Precursor in the Biosynthesis of Prenylated Indole Alkaloids in a Marine-Derived Fungus, Aspergillus sp by Tsukamoto, Sachiko, Kato, Hikaru, Greshock, Thomas J, Hirota, Hiroshi, Ohta, Tomihisa, Williams, Robert M

    Published in Journal of the American Chemical Society (25-03-2009)
    “…Notoamide E was identified to be a short-lived precursor in the biosynthesis of prenylated indole alkaloids in the mussel-derived Aspergillus sp. In addition,…”
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  5. 5

    Anti-inflammatory and Anti-melanogenic Proanthocyanidin Oligomers from Peanut Skin by Tatsuno, Takanori, Jinno, Megumi, Arima, Yukiko, Kawabata, Tetsuro, Hasegawa, Tatsuya, Yahagi, Nobuo, Takano, Fumihide, Ohta, Tomihisa

    “…Peanut skin (Arachis hypogaea L., Fabaceae) is an abundant source for polyphenols, such as proanthocyanidin oligomers. To determine whether proanthocyanidin…”
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  6. 6

    CYP3A4 Inhibitors Isolated from Licorice by Tsukamoto, Sachiko, Aburatani, Maki, Yoshida, Tomohiro, Yamashita, Yuko, El-beih, Ahmed Atef, Ohta, Tomihisa

    Published in Biological & Pharmaceutical Bulletin (01-10-2005)
    “…The extract of licorice (Glycyrrhiza uralensis FISHER, Leguminosae) showed CYP3A4 inhibitory activity with the IC50 value of 0.022 mg/ml. Bioassay-guided…”
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  7. 7

    Role of Furanocoumarin Derivatives on Grapefruit Juice-Mediated Inhibition of Human CYP3A Activity by GUO, L.-Q, FUKUDA, K, OHTA, T, YAMAZOE, Y

    Published in Drug metabolism and disposition (01-07-2000)
    “…With juices of grapefruit and related fruits, possible relationships between contents of six different furanocoumarins and extents of inhibition of microsomal…”
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  8. 8

    Leucettamol A: A new inhibitor of Ubc13-Uev1A interaction isolated from a marine sponge, Leucetta aff. microrhaphis by Tsukamoto, Sachiko, Takeuchi, Tomoharu, Rotinsulu, Henki, Mangindaan, Remy E.P., van Soest, Rob W.M., Ukai, Kazuyo, Kobayashi, Hisayoshi, Namikoshi, Michio, Ohta, Tomihisa, Yokosawa, Hideyoshi

    Published in Bioorganic & medicinal chemistry (15-12-2008)
    “…Leucettamol A is the first inhibitor of Ubc13-Uev1A interaction. Such inhibitors are presumed to be leads for anti-cancer agents that upregulate activity of…”
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  9. 9

    Inhibition Selectivity of Grapefruit Juice Components on Human Cytochromes P450 by Tassaneeyakul, Wichittra, Guo, Lian-Qing, Fukuda, Katsuyuki, Ohta, Tomihisa, Yamazoe, Yasushi

    Published in Archives of biochemistry and biophysics (15-06-2000)
    “…Five compounds including furanocoumarin monomers (bergamottin, 6′,7′-dihydroxybergamottin (DHB)), furanocoumarin dimers…”
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  10. 10
  11. 11

    Hexylitaconic acid: A new inhibitor of p53–HDM2 interaction isolated from a marine-derived fungus, Arthrinium sp by Tsukamoto, Sachiko, Yoshida, Takushi, Hosono, Hidetaka, Ohta, Tomihisa, Yokosawa, Hideyoshi

    “…(−)-Hexylitaconic acid ( 1), a new inhibitor of p53–HDM2 interaction, was isolated from a culture of marine-derived fungus, Arthrinium sp. Compound 1 is the…”
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  12. 12

    Capsicum ethanol extracts and capsaicin enhance interleukin-2 and interferon-gamma production in cultured murine Peyer's patch cells ex vivo by Takano, Fumihide, Yamaguchi, Masaya, Takada, Satoko, Shoda, Satoko, Yahagi, Nobuo, Takahashi, Tomoya, Ohta, Tomihisa

    Published in Life sciences (1973) (03-04-2007)
    “…We investigated the effects of red pepper ( Capsicum annuum Lin.) extracts (capsicum extract) and its main pungent capsaicin on T helper 1 (Th1) and 2 (Th2)…”
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  13. 13

    Aqueous Extract of Peanut Skin and Its Main Constituent Procyanidin A1 Suppress Serum IgE and IgG1 Levels in Mice-Immunized with Ovalbumin by Takano, Fumihide, Takata, Takanobu, Yoshihara, Akio, Nakamura, Yuka, Arima, Yukiko, Ohta, Tomihisa

    Published in Biological & pharmaceutical bulletin (01-05-2007)
    “…In this study, we investigated the effects of an aqueous extract of peanut (Arachis hypogaea L.) seed skin (PSE) and its main constituent procyanidin A1 (PA)…”
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  14. 14

    Cytotoxic Fatty Acid from Pleurocybella porrigens by Hasegawa, Tatsuya, Ishibashi, Mayumi, Takata, Takanobu, Takano, Fumihide, Ohta, Tomihisa

    Published in Chemical & Pharmaceutical Bulletin (01-12-2007)
    “…The new conjugated ketonic fatty acid, porrigenic acid (1), was isolated as a cytotoxic constituent of Pleurocybella porrigens. The structure of 1 was…”
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  15. 15

    Garlic extract and its selected organosulphur constituents promote ileal immune responses ex vivo by Ota, Natsuko, Takano, Fumihide, Muroga, Shouta, Kawabata, Tetsuro, Ishigaki, Yasuhito, Yahagi, Nobuo, Ohta, Tomihisa

    Published in Journal of functional foods (01-01-2012)
    “…The effects of garlic extract and three organosulphur compounds of garlic on intestinal immune responses in mice were investigated. Peyer’s patch (PP) cells…”
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  16. 16

    Himeic acid A: a new ubiquitin-activating enzyme inhibitor isolated from a marine-derived fungus, Aspergillus sp by Tsukamoto, Sachiko, Hirota, Hiroshi, Imachi, Misako, Fujimuro, Masahiro, Onuki, Hiroyuki, Ohta, Tomihisa, Yokosawa, Hideyoshi

    Published in Bioorganic & medicinal chemistry letters (03-01-2005)
    “…[Display omitted] A new ubiquitin-activating enzyme (E1) inhibitor, himeic acid A, was isolated from a culture of marine-derived fungus, Aspergillus sp. The…”
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  17. 17

    Isolation of CYP3A4 Inhibitors from the Black Cohosh (Cimicifuga racemosa) by Tsukamoto, Sachiko, Aburatani, Maki, Ohta, Tomihisa

    “…Recent investigation on drug interaction has shown that some foods and herbal medicines increase the oral availability of a variety of CYP3A4 substrates, which…”
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  18. 18

    Monodictyquinone A: a New Antimicrobial Anthraquinone from a Sea Urchin-Derived Fungus Monodictys sp by El-Beih, Ahmed Atef, Kawabata, Tetsuro, Koimaru, Keiichiro, Ohta, Tomihisa, Tsukamoto, Sachiko

    Published in Chemical & pharmaceutical bulletin (01-01-2007)
    “…A new antimicrobial anthraquinone, 1,8-dihydroxy-2-methoxy-6-methylanthraquinone, monodictyquinone A (1), was isolated from a culture of a marine-derived…”
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  19. 19

    Isolation of Cytochrome P450 Inhibitors from Strawberry Fruit, Fragaria ananassa by Tsukamoto, Sachiko, Tomise, Kyoko, Aburatani, Maki, Onuki, Hiroyuki, Hirorta, Hiroshi, Ishiharajima, Eiji, Ohta, Tomihisa

    “…A new glycoside, 2-β-d-glucopyranosyloxy-4,6-dihydroxyisovalerophenone (3), was isolated from strawberry fruit along with…”
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  20. 20

    Secomycalolide A: A New Proteasome Inhibitor Isolated from a Marine Sponge of the Genus Mycale by Tsukamoto, Sachiko, Koimaru, Keiichirou, Ohta, Tomihisa

    Published in Marine drugs (01-06-2005)
    “…A new oxazole-containing proteasome inhibitor, secomycalolide A, together with known mycalolide A and 30-hydroxymycalolide A, was isolated from a marine sponge…”
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