Search Results - "Ohta, Junsuke"
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Klotho Protein Promotes Adipocyte Differentiation
Published in Endocrinology (Philadelphia) (01-08-2006)“…Mice with homozygous disruption of the klotho exhibit multiple age-related disorders and have barely detectable amounts of white adipose tissue. Although…”
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Upregulation of cAMP is a new functional signal pathway of Klotho in endothelial cells
Published in Biochemical and biophysical research communications (07-02-2003)“…We measured angiotensin I-converting enzyme (ACE) activity in a human endothelial cell to characterize the intracellular signal pathways of Klotho. COS-1 cells…”
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Klotho gene delivery suppresses oxidative stress in vivo
Published in Geriatrics & gerontology international (01-09-2007)“…Objective: Mice deficient in the klotho gene exhibit a syndrome resembling premature human aging. A recent report also suggested that klotho transgenic mice…”
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Anti-apoptotic and anti-senescence effects of Klotho on vascular endothelial cells
Published in Biochemical and biophysical research communications (20-01-2006)“…Klotho-mutated mice manifest multiple age-related disorders that are observed in humans. A recent study suggested that Klotho protein might function as an…”
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Klotho protein activates the PKC pathway in the kidney and testis and suppresses 25-hydroxyvitamin D3 1alpha-hydroxylase gene expression
Published in Endocrine (01-12-2004)“…Homozygous Klotho mutant (kl-/-) mice exhibit a variety of phenotypes resembling human aging, including arteriosclerosis, infertility, skin atrophy,…”
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ORIGINAL ARTICLE: BIOLOGY: Klotho gene delivery suppresses oxidative stress in vivo
Published in Geriatrics & gerontology international (01-09-2007)“…Mice deficient in the klotho gene exhibit a syndrome resembling premature human aging. A recent report also suggested that klotho transgenic mice exhibited a…”
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