Search Results - "Ohta, Isao"
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1
Virus-like particles with FLAG-tagged envelope protein as a tetravalent dengue vaccine candidate
Published in Scientific reports (02-09-2021)“…The global incidence of dengue, which is caused by dengue virus (DENV) infection, has grown dramatically in recent decades and secondary infection with…”
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2
Structural and immunological effects of skin cryoablation in a mouse model
Published in PloS one (30-03-2015)“…Cryoablation is therapeutically applied for various disorders in several organs, and skin diseases are typical targets as this cryotherapy has been widely used…”
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3
thin polymer membrane, nano-suit, enhancing survival across the continuum between air and high vacuum
Published in Proceedings of the National Academy of Sciences - PNAS (07-05-2013)“…Most multicellular organisms can only survive under atmospheric pressure. The reduced pressure of a high vacuum usually leads to rapid dehydration and death…”
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4
Identifying Active Progeny Virus Particles in Formalin-Fixed, Paraffin-Embedded Sections Using Correlative Light and Scanning Electron Microscopy
Published in Laboratory investigation (01-01-2023)“…Immunohistochemical analysis of formalin-fixed paraffin-embedded (FFPE) tissue blocks is routinely used to identify virus-infected cells. However, detecting…”
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5
A ‘NanoSuit’ successfully protects petals of cherry blossoms in high vacuum: examination of living plants in an FE-SEM
Published in Scientific reports (26-01-2018)“…Land plants have evolved on dry land and developed surface barriers to protect themselves from environmental stresses. We have previously reported that…”
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6
Kallikrein-related Peptidase 5 Functions in Proteolytic Processing of Profilaggrin in Cultured Human Keratinocytes
Published in The Journal of biological chemistry (14-06-2013)“…Filaggrin protein is synthesized in the stratum granulosum of the skin and contributes to the formation of the human skin barrier. Profilaggrin is cleaved by…”
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7
A ‘NanoSuit’ surface shield successfully protects organisms in high vacuum: observations on living organisms in an FE-SEM
Published in Proceedings of the Royal Society. B, Biological sciences (07-03-2015)“…Although extremely useful for a wide range of investigations, the field emission scanning electron microscope (FE-SEM) has not allowed researchers to observe…”
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8
In situ preparation of biomimetic thin films and their surface-shielding effect for organisms in high vacuum
Published in PloS one (13-11-2013)“…Self-standing biocompatible films have yet to be prepared by physical or chemical vapor deposition assisted by plasma polymerization because gaseous monomers…”
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9
A modified ‘NanoSuit®’ preserves wet samples in high vacuum: direct observations on cells and tissues in field-emission scanning electron microscopy
Published in Royal Society open science (01-03-2017)“…Although field-emission scanning electron microscopy (FE-SEM) has proven very useful in biomedical research, the high vacuum required (10−3 to 10−7 Pa)…”
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10
Agglutination of Human Polyomaviruses by Using a Tetravalent Glycocluster as a Cross-Linker
Published in ACS omega (01-09-2020)“…Two kinds of tetravalent double-headed sialo-glycosides with short/long spacers between the Neu5Acα2,6Galβ1,4GlcNAc unit and ethylene glycol tetraacetic acid…”
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11
Utility of Scanning Electron Microscopy Elemental Analysis Using the 'NanoSuit' Correlative Light and Electron Microscopy Method in the Diagnosis of Lanthanum Phosphate Deposition in the Esophagogastroduodenal Mucosa
Published in Diagnostics (Basel) (18-12-2019)“…We have recently developed the correlative light and electron microscopy of hematoxylin and eosin (H&E)-stained glass slides using the 'NanoSuit' method. The…”
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12
Direct profiling of the phospholipid composition of adult Caenorhabditis elegans using whole-body imaging mass spectrometry
Published in Analytical and bioanalytical chemistry (2015)“…A protocol for the direct analysis of the phospholipid composition in the whole body of adult soil nematode, Caenorhabditis elegans (C. elegans), was…”
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13
Dressing living organisms in a thin polymer membrane, the NanoSuit, for high-vacuum FE-SEM observation
Published in Microscopy (01-08-2014)“…Scanning electron microscopy (SEM) has made remarkable progress and has become an essential tool for observing biological materials at microscopic level…”
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14
Resistance of a rodent malaria parasite to a thymidylate synthase inhibitor induces an apoptotic parasite death and imposes a huge cost of fitness
Published in PloS one (16-06-2011)“…The greatest impediment to effective malaria control is drug resistance in Plasmodium falciparum, and thus understanding how resistance impacts on the…”
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15
Fabrication of a PTFE-filled waveguide for millimeter-wave components using SR direct etching
Published in Microsystem technologies (01-10-2008)“…PTFE is widely used as a microwave and millimeter-wave material. However, it is known that PTFE is a difficult material to cut at high precision by…”
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Journal Article Conference Proceeding -
16
Relationship between Triglyceride Concentrations and LDL Size Evaluated by Malondialdehyde-modified LDL
Published in Clinical chemistry (Baltimore, Md.) (01-05-2001)“…Hypertriglyceridemia is associated with decreased HDL-cholesterol (HDL-C) and increased small dense LDL. In addition, small dense LDL is known to be…”
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17
Analysis of intra-GBM microstructures in a SLE case with glomerulopathy associated with podocytic infolding
Published in Clinical and experimental nephrology (01-12-2008)“…Background Systemically podocytic infolding into the GBM which causes nonargyrophilic holes in the GBM in association with intra-GBM microstructures has been…”
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18
New composite right/left-handed transmission line using substrate integrated waveguide and metal-patches
Published in 2009 IEEE MTT-S International Microwave Symposium Digest (01-06-2009)“…A new composite right/left-handed transmission line (CRLH-TL) for millimeter wave frequency is proposed and investigated theoretically and experimentally. It…”
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Conference Proceeding -
19
Parallel-coupled microstrip filters with periodic floating-conductors on coupled-edges for spurious suppression
Published in 2008 IEEE MTT-S International Microwave Symposium Digest (01-06-2008)“…This paper presents a new technique for suppressing the spurious response of parallel-coupled microstrip bandpass filters at twice the design frequency…”
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Conference Proceeding -
20
A Parallel-Crossed H-Plane Waveguide Eight-Port Hybrid and Its Application to a Planar Magic Tee
Published in 2007 IEEE/MTT-S International Microwave Symposium (01-06-2007)“…This paper presents a novel eight-port hybrid constructed of four parallel-crossed H-plane rectangular waveguides. First, a basic constitution theory is…”
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Conference Proceeding