Search Results - "Ohsuga, J"

Inhibition of diet-induced atheroma formation in transgenic mice expressing apolipoprotein E in the arterial wall by Shimano, H, Ohsuga, J, Shimada, M, Namba, Y, Gotoda, T, Harada, K, Katsuki, M, Yazaki, Y, Yamada, N

“…Apolipoprotein E (apoE) plays a crucial role in lipoprotein metabolism both in plasma and in peripheral tissues. To test whether apoE in the vascular wall has…”
Get full text

Expression of platelet-derived growth factor beta receptor on human monocyte-derived macrophages and effects of platelet-derived growth factor BB dimer on the cellular function by INABA, T, SHIMANO, H, GOTODA, T, HARADA, K, SHIMADA, M, OHSUGA, J.-I, WATANABE, Y, KAWAMURA, M, YAZAKI, Y, YAMADA, N

“…Platelet-derived growth factor (PDGF) plays an important role in the process of atherosclerosis which is characterized by the presence of macrophage-derived…”
Get full text

Transcription factor PU.1 mediates induction of c-fms in vascular smooth muscle cells: a mechanism for phenotypic change to phagocytic cells by Inaba, Toshimori, Gotoda, Takanari, Ishibashi, Shun, Harada, Kenji, Ohsuga, Jun-Ichi, Ohashi, Ken, Yazaki, Yoshio, Yamada, Nobuhiro

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Secretion-recapture process of apolipoprotein E in hepatic uptake of chylomicron remnants in transgenic mice by SHIMANO, H, NAMBA, Y, OHSUGA, J, KAWAMURA, M, YAMAMOTO, K, SHIMADA, M, GOTODA, T, HARADA, K, YAZAKI, Y, YAMADA, N

“…To investigate the role of apoE in hepatic uptake of chylomicron remnants, we studied chylomicron metabolism in transgenic mice overexpressing apoE in the…”
Get full text

Overexpression of apolipoprotein E prevents development of diabetic hyperlipidemia in transgenic mice by Yamamoto, K., Shimano, H., Shimada, M., Kawamura, M., Gotoda, T., Harada, K., Ohsuga, J., Yazaki, Y., Yamada, N.

“…Overexpression of apolipoprotein E prevents development of diabetic hyperlipidemia in transgenic mice. K Yamamoto , H Shimano , M Shimada , M Kawamura , T…”
Get full text

Overexpression of Human Lipoprotein Lipase Increases Hormone-Sensitive Lipase Activity in Adipose Tissue of Mice by Shimada, M., Ishibashi, S., Yamamoto, K., Kawamura, M., Watanabe, Y., Gotoda, T., Harada, K., Inaba, T., Ohsuga, J., Yazaki, Y., Yamada, N.

“…An elevation of lipoprotein lipase (LPL) activity in adipose tissue is considered a possible cause of obesity. However, transgenic mice that overexpress the…”
Get full text

Cholesteryl ester transfer protein deficiency caused by a nonsense mutation detected in the patient's macrophage mRNA by Gotoda, T, Kinoshita, M, Shimano, H, Harada, K, Shimada, M, Ohsuga, J, Teramoto, T, Yazaki, Y, Yamada, N

“…Cholesteryl ester transfer protein (CETP) deficiency causes marked elevation of plasma high-density lipoproteins, termed hyperalphalipoproteinemia. Only one…”
Get more information

Effects of Platelet-Derived Growth Factor on the Synthesis of Lipoprotein Lipase in Human Monocyte-Derived Macrophages by Inaba, Toshimori, Kawamura, Masako, Gotoda, Takanari, Harada, Kenji, Shimada, Masako, Ohsuga, Jun-ichi, Shimano, Hitoshi, Akanuma, Yasuo, Yazaki, Yoshio, Yamada, Nobuhiro

“…Lipoprotein lipase (LPL), which is secreted by the two predominant cell types in atherosclerotic plaque, macrophages and smooth muscle cells, may be involved…”
Get full text

Overexpression of human lipoprotein lipase enhances uptake of lipoproteins containing apolipoprotein B-100 in transfected cells by KAWAMURA, M, SHIMANO, H, YAZAKI, Y, YAMADA, N, GOTODA, T, HARADA, K, SHIMADA, M, OHSUGA, J.-I, INABA, T, WATANABE, Y, YAMAMOTO, K, KOZAKI, K

“…To investigate the role in lipoprotein metabolism of lipoprotein lipase (LPL) secreted by tissues, we established two cell lines. Fusion plasmids containing…”
Get full text

Overexpression of apolipoprotein E prevents development of diabetic hyperlipidemia in transgenic mice by YAMAMOTO, K, SHIMANO, H, SHIMADA, M, KAWAMURA, M, GOTODA, T, HARADA, K, OHSUGA, J.-I, YAZAKI, Y, YAMADA, N

“…To determine the role of apolipoprotein E (apoE) in diabetic hyperlipidemia, we induced diabetes in transgenic mice overexpressing apoE by intravenous…”
Get full text

Dextran sulfate, a competitive inhibitor for scavenger receptor, prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbits by Tsubamoto, Y, Yamada, N, Watanabe, Y, Inaba, T, Shiomi, M, Shimano, H, Gotoda, T, Harada, K, Shimada, M, Ohsuga, J

“…Dextran sulfate competes with binding of modified LDL to the scavenger receptor in macrophages. To elucidate the role of dextran sulfate in the atherosclerotic…”
Get more information

Metabolism of chylomicron remnants in transgenic mice expressing apolipoprotein E in the intestine by Shimano, H, Namba, Y, Ohsuga, J, Yamamoto, K, Shimada, M, Gotoda, T, Harada, K, Yazaki, Y, Yamada, N

“…Apolipoprotein E (apoE) has high affinity for the cell surface low density lipoprotein (LDL) receptor. To determine the role of apoE in plasma chylomicron…”
Get more information

Induction of Macrophage Colony-stimulating Factor Receptor (c-fms) Expression in Vascular Medial Smooth Muscle Cells Treated with Heparin Binding Epidermal Growth Factor-like Growth Factor by Inaba, T, Ishibashi, S, Harada, K, Ohsuga, J, Ohashi, K, Yagyu, H, Yazaki, Y, Higashiyama, S, Kawata, S, Matsuzawa, Y, Yamada, N

“…Vascular smooth muscle cells migrate, proliferate, and transform to foam cells during the atherosclerotic process. We have reported that smooth muscle cells…”
Get full text

Overexpression of Human Lipoprotein Lipase Protects Diabetic Transgenic Mice From Diabetic Hypertriglyceridemia and Hypercholesterolemia by Shimada, Masako, Ishibashi, Shun, Gotoda, Takanari, Kawamura, Masako, Yamamoto, Koji, Inaba, Toshimori, Harada, Kenji, Ohsuga, Junichi, Perrey, Stephane, Yazaki, Yoshio, Yamada, Nobuhiro

“…We investigated the role of the overexpression of lipoprotein lipase (LPL) in lipoprotein abnormalities in transgenic mice with streptozotocin-induced diabetes…”
Get full text

Induction of sustained expression of proto-oncogene c-fms by platelet-derived growth factor, epidermal growth factor, and basic fibroblast growth factor, and its suppression by interferon-gamma and macrophage colony-stimulating factor in human aortic medial smooth muscle cells by Inaba, T, Gotoda, T, Harada, K, Shimada, M, Ohsuga, J, Ishibashi, S, Yazaki, Y, Yamada, N

“…Vascular medial smooth muscle cells migrate, proliferate and transform to foam cells in the process of atherosclerosis. We have reported that the intimal…”
Get full text

Role of macrophage colony-stimulating factor in the initial process of atherosclerosis by Watanabe, Y, Inaba, T, Gotoda, T, Harada, K, Shimada, M, Ohsuga, J, Kawamura, M, Yazaki, Y, Yamada, N

“…The early atherosclerotic lesion is characterized by the presence of macrophage-derived foam cells. Macrophage colony-stimulating factor (M-CSF) specifically…”
Get more information

Plasma lipid abnormalities and risk factors for coronary artery disease in Japanese subjects with diabetes mellitus and glucose intolerance by Yamada, N, Yoshinaga, H, Gotoda, T, Harada, K, Shimada, M, Ohsuga, J, Akanuma, Y, Murase, T

“…We evaluated the plasma lipid levels of 3163 subjects including subjects with non-insulin-dependent diabetes mellitus (NIDDM), insulin-dependent diabetes…”
Get more information