Search Results - "Ohshima, Yasumi"
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Control of body size in C. elegans dependent on food and insulin/IGF‐1 signal
Published in Genes to cells : devoted to molecular & cellular mechanisms (01-06-2011)“…The body size of an organism is governed by genetic and environmental factors. As an environmental factor, food appears to be the most important for body size…”
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The Importance of cGMP Signaling in Sensory Cilia for Body Size Regulation in Caenorhabditis elegans
Published in Genetics (Austin) (01-12-2015)“…The body size of Caenorhabditis elegans is thought to be controlled by sensory inputs because many mutants with sensory cilium structure defects exhibit small…”
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The C. elegans che-1 gene encodes a zinc finger transcription factor required for specification of the ASE chemosensory neurons
Published in Development (Cambridge) (01-04-2003)“…Chemotaxis to water-soluble chemicals such as NaCl is an important behavior of C. elegans when seeking food. ASE chemosensory neurons have a major role in this…”
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Neural regulation of thermotaxis in Caenorhabditis elegans
Published in Nature (London) (27-07-1995)“…Thermal stimulus is an important environmental factor influencing animal behaviour. However, the mechanisms underlying thermosensation and thermal adaptation…”
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ADBP-1 Regulates an ADAR RNA-Editing Enzyme to Antagonize RNA-Interference-Mediated Gene Silencing in Caenorhabditis elegans
Published in Genetics (Austin) (01-10-2008)“…Small interfering RNAs (siRNAs) and microRNAs (miRNAs) mediate gene silencing through evolutionarily conserved pathways. In Caenorhabditis elegans, the…”
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A novel zf-MYND protein, CHB-3, mediates guanylyl cyclase localization to sensory cilia and controls body size of Caenorhabditis elegans
Published in PLoS genetics (01-11-2010)“…Cilia are important sensory organelles, which are thought to be essential regulators of numerous signaling pathways. In Caenorhabditis elegans, defects in…”
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Cyclic GMP-dependent protein kinase EGL-4 controls body size and lifespan in C. elegans
Published in Development (Cambridge) (01-03-2003)“…We designed an automatic system to measure body length, diameters and volume of a C. elegans worm. By using this system, mutants with an increased body volume…”
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Mutants carrying two sma mutations are super small in the nematode C. elegans
Published in Genes to cells : devoted to molecular & cellular mechanisms (01-05-2007)“…Body size determination is critical for multicellular organisms; however, the mechanisms remain largely unknown. Mutations that alter body size were studied to…”
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Mutations in a Cyclic Nucleotide–Gated Channel Lead to Abnormal Thermosensation and Chemosensation in C. elegans
Published in Neuron (Cambridge, Mass.) (01-10-1996)“…The C. elegans tax-4 mutants are abnormal in multiple sensory behaviors: they fail to respond to temperature or to water-soluble or volatile chemical…”
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Regulation of Interneuron Function in the C. elegans Thermoregulatory Pathway by the ttx-3 LIM Homeobox Gene
Published in Neuron (Cambridge, Mass.) (01-08-1997)“…Neural pathways, which couple temperature-sensing neurons to motor and autonomic outputs, allow animals to navigate away from and adjust metabolism rates in…”
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Nucleocytoplasmic transport of fluorescent mRNA in living mammalian cells: nuclear mRNA export is coupled to ongoing gene transcription
Published in Genes to cells : devoted to molecular & cellular mechanisms (01-03-2006)“…In eukaryotic cells, export of mRNA from the nucleus to the cytoplasm is one of the essential steps in gene expression. To examine mechanisms involved in the…”
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Control of body size by SMA-5, a homolog of MAP kinase BMK1/ERK5, in C. elegans
Published in Development (Cambridge) (01-07-2005)“…We have analyzed the sma-5(n678) mutant in C. elegans to elucidate mechanisms controlling body size. The sma-5 mutant is very small, grows slowly and its…”
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SRC-1, a non-receptor type of protein tyrosine kinase, controls the direction of cell and growth cone migration in C. elegans
Published in Development (Cambridge) (01-12-2005)“…Src family tyrosine kinase (SFK) has been implicated in the regulation of cell adhesion and migration during animal development. We show that SRC-1, an…”
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Mouse ULK2, a novel member of the UNC-51-like protein kinases: unique features of functional domains
Published in Oncogene (21-10-1999)“…The UNC-51 serine/threonine kinase of C. elegans plays an essential role in axonal elongation, and unc-51 mutants exhibit uncoordinated movements. We have…”
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The nucleolus is involved in mRNA export from the nucleus in fission yeast
Published in Journal of cell science (15-06-2004)“…To elucidate the mechanism of mRNA export from the nucleus, we isolated five novel temperature-sensitive mutants (ptr7 to ptr11) that accumulate poly(A)(+) RNA…”
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Body size change in various nematodes depending on bacterial food, sex and growth temperature
Published in Worm (Austin, TX) (01-04-2012)“…We previously reported significant body size change in the nematode Caenorhabditis elegans, depending on the food strain of E. coli. Here, we examined this…”
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cGMP and a germ‐line signal control body size in C. elegans through cGMP‐dependent protein kinase EGL‐4
Published in Genes to cells : devoted to molecular & cellular mechanisms (01-09-2004)“…Mechanisms involved in the control of body size are largely unknown. In the nematode C. elegans, several small body size mutants were isolated, and the…”
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Participation of XPB/Ptr8p, a component of TFIIH, in nucleocytoplasmic transport of mRNA in fission yeast
Published in Genes to cells : devoted to molecular & cellular mechanisms (01-01-2007)“…To identify novel factors involved in nuclear mRNA export in Schizosaccharomyces pombe, we isolated and characterized the ptr8+ gene, mutation of which causes…”
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Active uptake of artificial particles in the nematode Caenorhabditis elegans
Published in Journal of experimental biology (01-04-2012)“…Feeding and food choice are crucial to the survival of an animal. The nematode Caenorhabditis elegans feeds on various microorganisms in nature, and is usually…”
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Functional reconstitution of a heteromeric cyclic nucleotide-gated channel of Caenorhabditis elegans in cultured cells
Published in Brain research (06-03-1999)“…The tax-4 and tax-2 genes of Caenorhabditis elegans are essential for normal olfaction, gustation, and thermosensation, suggesting that they have a role in…”
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