Search Results - "Ohshima, Kousei"

Secreted Frizzled-related Protein 5 Diminishes Cardiac Inflammation and Protects the Heart from Ischemia/Reperfusion Injury by Nakamura, Kazuto, Sano, Soichi, Fuster, José J., Kikuchi, Ryosuke, Shimizu, Ippei, Ohshima, Kousei, Katanasaka, Yasufumi, Ouchi, Noriyuki, Walsh, Kenneth

“…Wnt signaling has diverse actions in cardiovascular development and disease processes. Secreted frizzled-related protein 5 (Sfrp5) has been shown to function…”
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Possible Role of Angiotensin-Converting Enzyme 2 and Activation of Angiotensin II Type 2 Receptor by Angiotensin-(1–7) in Improvement of Vascular Remodeling by Angiotensin II Type 1 Receptor Blockade by Ohshima, Kousei, Mogi, Masaki, Nakaoka, Hirotomo, Iwanami, Jun, Min, Li-Juan, Kanno, Harumi, Tsukuda, Kana, Chisaka, Toshiyuki, Bai, Hui-Yu, Wang, Xiao-Li, Ogimoto, Akiyoshi, Higaki, Jitsuo, Horiuchi, Masatsugu

“…Cross talk between the angiotensin-converting enzyme (ACE)/angiotensin II (Ang II)/Ang II type 1 (AT1) receptor axis and the ACE2/Ang-(1–7)/Mas axis plays a…”
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Direct angiotensin II type 2 receptor stimulation ameliorates insulin resistance in type 2 diabetes mice with PPARγ activation by Ohshima, Kousei, Mogi, Masaki, Jing, Fei, Iwanami, Jun, Tsukuda, Kana, Min, Li-Juan, Ogimoto, Akiyoshi, Dahlöf, Björn, Steckelings, Ulrike M, Unger, Tomas, Higaki, Jitsuo, Horiuchi, Masatsugu

“…The role of angiotensin II type 2 (AT(2)) receptor stimulation in the pathogenesis of insulin resistance is still unclear. Therefore we examined the…”
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Direct stimulation of angiotensin II type 2 receptor enhances spatial memory by Jing, Fei, Mogi, Masaki, Sakata, Akiko, Iwanami, Jun, Tsukuda, Kana, Ohshima, Kousei, Min, Li-Juan, Steckelings, Ulrike M, Unger, Thomas, Dahlöf, Björn, Horiuchi, Masatsugu

“…We examined the possibility that direct stimulation of the angiotensin II type 2 (AT2) receptor by a newly generated direct AT2 receptor agonist, Compound 21…”
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Direct Stimulation of Angiotensin II Type 2 Receptor Initiated After Stroke Ameliorates Ischemic Brain Damage by Min, Li-Juan, Mogi, Masaki, Tsukuda, Kana, Jing, Fei, Ohshima, Kousei, Nakaoka, Hirotomo, Kan-no, Harumi, Wang, Xiao-Li, Chisaka, Toshiyuki, Bai, Hui-Yu, Iwanami, Jun, Horiuchi, Masatsugu

“…BACKGROUND Stroke is a leading cause of death and disability; however, meta-analysis of randomized controlled trials of blood pressure-lowering drugs in acute…”
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Roles of Interleukin 17 in Angiotensin II Type 1 Receptor–Mediated Insulin Resistance by Ohshima, Kousei, Mogi, Masaki, Jing, Fei, Iwanami, Jun, Tsukuda, Kana, Min, Li-Juan, Higaki, Jitsuo, Horiuchi, Masatsugu

“…Interleukin 17 (IL-17) is known to contribute to the pathogenesis of hypertension, atherosclerosis, and adipocyte differentiation; however, the roles of IL-17…”
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Role of angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas axis in the hypotensive effect of azilsartan by Iwanami, Jun, Mogi, Masaki, Tsukuda, Kana, Wang, Xiao-Li, Nakaoka, Hirotomo, Ohshima, Kousei, Chisaka, Toshiyuki, Bai, Hui-Yu, Kanno, Harumi, Min, Li-Juan, Horiuchi, Masatsugu

“…The possible counteracting effect of angiotensin (Ang)-converting enzyme (ACE)2/Ang-(1-7)/Mas axis against the ACE/Ang II/Ang II type 1 (AT1) receptor axis in…”
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Complete definite positive spasm on acetylcholine spasm provocation tests: comparison of clinical positive spasm by Sueda, Shozo, Miyoshi, Toru, Sasaki, Yasuhiro, Ohshima, Kousei, Sakaue, Tomoki, Habara, Hirokazu, Kohno, Hiroaki

“…In the clinical grounds, patients with ≥90 % luminal narrowing during acetylcholine (ACh) testing had variable response. We investigated ischemic findings and…”
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Effect of angiotensin II type 2 receptor-interacting protein on adipose tissue function via modulation of macrophage polarization by Jing, Fei, Mogi, Masaki, Min, Li-Juan, Ohshima, Kousei, Nakaoka, Hirotomo, Tsukuda, Kana, Wang, Xiaoli, Iwanami, Jun, Horiuchi, Masatsugu

“…We demonstrated that angiotensin II type 2 (AT2) receptor-interacting protein (ATIP) 1 ameliorates inflammation-mediated vascular remodeling independent of the…”
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Effect of Angiotensin II Type 2 Receptor Deletion in Hematopoietic Cells on Brain Ischemia-Reperfusion Injury by Iwanami, Jun, Mogi, Masaki, Tsukuda, Kana, Min, Li-Juan, Sakata, Akiko, Jing, Fei, Ohshima, Kousei, Horiuchi, Masatsugu

“…The angiotensin II type 2 (AT2) receptor is expressed in bone marrow cells and may affect cell differentiation. We previously reported a beneficial role of the…”
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Role of Peroxisome Proliferator-Activated Receptor-γ in Vascular Inflammation by Ohshima, Kousei, Mogi, Masaki, Horiuchi, Masatsugu

“…Vascular inflammation plays a crucial role in atherosclerosis, and its regulation is important to prevent cerebrovascular and coronary artery disease. The…”
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Angiotensin II type 2 receptor signaling affects dopamine levels in the brain and prevents binge eating disorder by Nakaoka, Hirotomo, Mogi, Masaki, Kan-no, Harumi, Tsukuda, Kana, Ohshima, Kousei, Wang, Xiao-Li, Chisaka, Toshiyuki, Bai, Hui-Yu, Shan, Bao-Shuai, Kukida, Masayoshi, Iwanami, Jun, Horiuchi, Masatsugu

“…Introduction: Binge eating disorder (BED) is associated with dopaminergic activation as food reward, resulting in metabolism-related disorders. Stimulation of…”
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Influence of angiotensin II type 1 receptor-associated protein on prenatal development and adult hypertension after maternal dietary protein restriction during pregnancy by Tsukuda, Kana, Mogi, Masaki, Iwanami, Jun, Min, Li-Juan, Jing, Fei, Ohshima, Kousei, Horiuchi, Masatsugu

“…An adverse relationship between suboptimal fetal environments and the development of adult diseases, such as hypertension, type II diabetes, and cardiovascular…”
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Cavity volume of ruptured plaque is an independent predictor for angiographic no-reflow phenomenon during primary angioplasty in patients with ST-segment elevation myocardial infarction by Ohshima, Kousei, MD, Ikeda, Shuntaro, MD, Kadota, Hisaki, MD, Yamane, Kenichi, MD, Izumi, Naoki, MD, Kawazoe, Hiroshi, MD, Ohshima, Kiyotaka, MD, Hamada, Mareomi, MD, FJCC

“…Summary Background Plaque rupture plays a critical role for the development of acute myocardial infarction. However, whether quantitative parameters with…”
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Relationship between plaque composition and no-reflow phenomenon following primary angioplasty in patients with ST-segment elevation myocardial infarction—Analysis with virtual histology intravascular ultrasound by Ohshima, Kousei, MD, Ikeda, Shuntaro, MD, Watanabe, Kouki, MD, Yamane, Kenichi, MD, Izumi, Naoki, MD, Ishibashi, Ken, MD, Ohshima, Kiyotaka, MD, Hamada, Mareomi, MD, FJCC

“…Summary Background The angiographic no-reflow phenomenon after primary percutaneous coronary intervention (PCI) carries a poor prognosis in patients with…”
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Improvement of cognitive impairment in female type 2 diabetes mellitus mice by spironolactone by Sakata, Akiko, Mogi, Masaki, Iwanami, Jun, Tsukuda, Kana, Min, Li-Juan, Jing, Fei, Ohshima, Kousei, Ito, Masaharu, Horiuchi, Masatsugu

“…Patients with type 2 diabetes mellitus (T2DM) exhibit more severe cognitive decline in females compared with males; however, the preventive approach to this…”
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Angiotensin II type 2 receptor-interacting protein prevents vascular senescence by Min, Li-Juan, Mogi, Masaki, Iwanami, Jun, Jing, Fei, Tsukuda, Kana, Ohshima, Kousei, Horiuchi, Masatsugu

“…Angiotensin II type 2 (AT(2)) receptor-interacting protein (ATIP), which interacts with the C-terminal tail of the AT(2) receptor, regulates the functions of…”
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Angiotensin II and aldosterone-induced neuronal damage in neurons through an astrocyte-dependent mechanism by Min, Li-Juan, Mogi, Masaki, Iwanami, Jun, Sakata, Akiko, Jing, Fei, Tsukuda, Kana, Ohshima, Kousei, Horiuchi, Masatsugu

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Inhibition of MCP-1/CCR2 signaling pathway is involved in synergistic inhibitory effects of irbesartan with rosuvastatin on vascular remodeling by Ohshima, Kousei, Mogi, Masaki, Nakaoka, Hirotomo, Jing, Fei, Iwanami, Jun, Min, Li-Juan, Tsukuda, Kana, Kanno, Harumi, Ogimoto, Akiyoshi, Higaki, Jitsuo, Horiuchi, Masatsugu

“…Additional beneficial effects of angiotensin II type 1 (AT(1)) receptor blockers beyond AT(1) receptor blockade have been highlighted. Irbesartan is reported…”
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Female type 2 diabetes mellitus mice exhibit severe ischemic brain damage by Sakata, Akiko, Mogi, Masaki, Iwanami, Jun, Tsukuda, Kana, Min, Li-Juan, Jing, Fei, Ohshima, Kousei, Ito, Masaharu, Horiuchi, Masatsugu

“…Type 2 diabetes can impair the outcome of stroke as well as increase stroke risk; however, the sex difference in ischemic brain damage is not well known, and…”
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