Search Results - "Ohori, N"

Highly Accurate Diagnosis of Cancer in Thyroid Nodules With Follicular Neoplasm/Suspicious for a Follicular Neoplasm Cytology by ThyroSeq v2 Next-Generation Sequencing Assay by NIKIFOROV, Yuri E, CARTY, Sally E, SEETHALA, Raja R, TUBLIN, Mitchell E, YIP, Linwah, NIKIFOROVA, Marina N, CHIOSEA, Simon I, COYNE, Christopher, DUVVURI, Umamaheswar, FERRIS, Robert L, GOODING, William E, HODAK, Steven P, LEBEAU, Shane O, PAUL OHORI, N

“…Fine-needle aspiration (FNA) cytology is a common approach to evaluating thyroid nodules, although 20% to 30% of FNAs have indeterminate cytology, which…”
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Impact of Mutational Testing on the Diagnosis and Management of Patients with Cytologically Indeterminate Thyroid Nodules: A Prospective Analysis of 1056 FNA Samples by Nikiforov, Yuri E, Ohori, N. Paul, Hodak, Steven P, Carty, Sally E, LeBeau, Shane O, Ferris, Robert L, Yip, Linwah, Seethala, Raja R, Tublin, Mitchell E, Stang, Michael T, Coyne, Christopher, Johnson, Jonas T, Stewart, Andrew F, Nikiforova, Marina N

“…Context: Thyroid nodules are common in adults, but only a small fraction of them is malignant. Fine-needle aspiration (FNA) cytology provides a definitive…”
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Preoperative next-generation sequencing of pancreatic cyst fluid is highly accurate in cyst classification and detection of advanced neoplasia by Singhi, Aatur D, McGrath, Kevin, Brand, Randall E, Khalid, Asif, Zeh, Herbert J, Chennat, Jennifer S, Fasanella, Kenneth E, Papachristou, Georgios I, Slivka, Adam, Bartlett, David L, Dasyam, Anil K, Hogg, Melissa, Lee, Kenneth K, Marsh, James Wallis, Monaco, Sara E, Ohori, N Paul, Pingpank, James F, Tsung, Allan, Zureikat, Amer H, Wald, Abigail I, Nikiforova, Marina N

“…DNA-based testing of pancreatic cyst fluid (PCF) is a useful adjunct to the evaluation of pancreatic cysts (PCs). Mutations in / are highly specific for…”
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Follicular Neoplasm of Thyroid Revisited: Current Differential Diagnosis and the Impact of Molecular Testing by Ohori, N. Paul, Nishino, Michiya

“…The diagnosis of “follicular neoplasm” (FN) in thyroid cytopathology has a long history that originated not long after the practice of fine-needle aspiration…”
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Evolving concepts in thyroid cytology by Ohori, N. Paul

“…Concepts in thyroid diagnostics are evolving. As cytopathologists, we benefit from understanding the changes taking place in cytopathology practice as well as…”
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Impact of the Multi-Gene ThyroSeq Next-Generation Sequencing Assay on Cancer Diagnosis in Thyroid Nodules with Atypia of Undetermined Significance/Follicular Lesion of Undetermined Significance Cytology by Nikiforov, Yuri E, Carty, Sally E, Chiosea, Simon I, Coyne, Christopher, Duvvuri, Umamaheswar, Ferris, Robert L, Gooding, William E, LeBeau, Shane O, Ohori, N Paul, Seethala, Raja R, Tublin, Mitchell E, Yip, Linwah, Nikiforova, Marina N

“…Fine-needle aspiration (FNA) cytology is a common approach to evaluate thyroid nodules. It offers definitive diagnosis of a benign or malignant nodule in the…”
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Molecular alterations in Hürthle cell nodules and preoperative cancer risk by Doerfler, William R, Nikitski, Alyaksandr V, Morariu, Elena M, Ohori, N Paul, Chiosea, Simion I, Landau, Michael S, Nikiforova, Marina N, Nikiforov, Yuri E, Yip, Linwah, Manroa, Pooja

“…Hürthle cell carcinoma (HCC) is a distinct type of thyroid cancer genetically characterized by DNA copy number alterations (CNA), typically of genome…”
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Molecular testing and thyroid nodule management in North America by Ohori, N. Paul

“…The incidence of thyroid cancer is rising for a variety of reasons. At the same time, the nomenclature revision of non-invasive encapsulated follicular-variant…”
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Integrating next-generation sequencing to endoscopic retrograde cholangiopancreatography (ERCP)-obtained biliary specimens improves the detection and management of patients with malignant bile duct strictures by Singhi, Aatur D, Nikiforova, Marina N, Chennat, Jennifer, Papachristou, Georgios I, Khalid, Asif, Rabinovitz, Mordechai, Das, Rohit, Sarkaria, Savreet, Ayasso, M Samir, Wald, Abigail I, Monaco, Sara E, Nalesnik, Michael, Ohori, N Paul, Geller, David, Tsung, Allan, Zureikat, Amer H, Zeh, Herbert, Marsh, J Wallis, Hogg, Melissa, Lee, Kenneth, Bartlett, David L, Pingpank, James F, Humar, Abhinav, Bahary, Nathan, Dasyam, Anil K, Brand, Randall, Fasanella, Kenneth E, McGrath, Kevin, Slivka, Adam

“…Despite improvements in imaging, serum CA19-9 and pathological evaluation, differentiating between benign and malignant bile duct strictures remains a…”
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A decade into thyroid molecular testing: where do we stand? by Ohori, N. Paul

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Adequacy of Core Needle Biopsy Specimens and Fine-Needle Aspirates for Molecular Testing of Lung Adenocarcinomas by Schneider, Frank, Smith, Matthew A., Lane, Molly C., Pantanowitz, Liron, Dacic, Sanja, Ohori, N. Paul

“…Objectives: Molecular testing of lung adenocarcinomas for epidermal growth factor (EGFR) mutations and an anaplastic lymphoma kinase (ALK) translocation is…”
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Performance Characteristics of Incisional and Core Needle Biopsies for Diagnosis in Parotid Gland: Single-Institutional Experience and Assessment of the Value of a Milan System for Reporting Salivary Gland Cytopathology-Like Risk Stratification Model by Rammal, Rayan, Wang, Qian, Ohori, N Paul, Kubik, Mark, Chiosea, Simion I, Seethala, Raja R

“…Unlike parotid fine-needle aspiration biopsy, standardized reporting for core needle biopsy (CNB) and incisional biopsy (IB) is not established. To examine the…”
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Benign call rate and molecular test result distribution of ThyroSeq v3 by Ohori, N. Paul, Landau, Michael S., Carty, Sally E., Yip, Linwah, LeBeau, Shane O., Manroa, Pooja, Seethala, Raja R., Schoedel, Karen E., Nikiforova, Marina N., Nikiforov, Yuri E.

“…Background The benign call rate (BCR) is the percentage of cytomorphologically indeterminate cases with subsequent benign or negative molecular results. For…”
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Preoperative detection of RAS mutation may guide extent of thyroidectomy by Patel, Snehal G., MD, Carty, Sally E., MD, McCoy, Kelly L., MD, Ohori, N. Paul, MD, LeBeau, Shane O., MD, Seethala, Raja R., MD, Nikiforova, Marina N., MD, Nikiforov, Yuri E., MD, PhD, Yip, Linwah, MD

“…Background Preoperative detection of RAS mutations can contribute to cancer risk assessment in indeterminate thyroid nodules, although RAS is not always…”
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Variability in the Atypia of Undetermined Significance/Follicular Lesion of Undetermined Significance Diagnosis in the Bethesda System for Reporting Thyroid Cytopathology: Sources and Recommendations by Ohori, N. Paul, Schoedel, Karen E.

“…Objective: Of the 6 categories in the Bethesda System for Reporting Thyroid Cytopathology (BSRTC), the atypia of undetermined significance/follicular lesion of…”
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Usefulness of Immunohistochemical and Histochemical Studies in the Classification of Lung Adenocarcinoma and Squamous Cell Carcinoma in Cytologic Specimens by OCQUE, Rebecca, TOCHIGI, Naobumi, OHORI, N. Paul, DACIC, Sanja

“…Histologic subtyping of non-small cell lung carcinoma (NSCLC) is important because the efficacy of new treatments depends on tumor histologic features. We…”
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The incidence of cancer and rate of false-negative cytology in thyroid nodules greater than or equal to 4 cm in size by McCoy, Kelly L., MD, Jabbour, Noel, Ogilvie, Jennifer B., MD, Ohori, N. Paul, MD, Carty, Sally E., MD, Yim, John H., MD

“…Background High false-negative rates for fine needle aspiration biopsy (FNAB) of thyroid nodules greater than 3 cm have prompted recommendations for diagnostic…”
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The Clinical Utility of Molecular Testing in the Management of Thyroid Follicular Neoplasms (Bethesda IV Nodules) by Carty, Sally E., Ohori, N. Paul, Hilko, Dane A., McCoy, Kelly L., French, Esra K., Manroa, Pooja, Morariu, Elena, Sridharan, Shaum, Seethala, Raja R., Yip, Linwah

“…OBJECTIVE:FN present a management quandary as they are often benign but may also be aggressive TC. Consensus recommendations have historically advised…”
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Correct extent of thyroidectomy is poorly predicted preoperatively by the guidelines of the American Thyroid Association for low and intermediate risk thyroid cancers by Dhir, Mashaal, McCoy, Kelly L., Ohori, N. Paul, Adkisson, Cameron D., LeBeau, Shane O., Carty, Sally E., Yip, Linwah

“…Recent guidelines from the American Thyroid Association recommend thyroid lobectomy for intrathyroidal differentiated thyroid cancers <4 cm. Our aim was to…”
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Tumor Genotype Determines Phenotype and Disease-related Outcomes in Thyroid Cancer: A Study of 1510 Patients by Yip, Linwah, Nikiforova, Marina N, Yoo, Jenny Y, McCoy, Kelly L, Stang, Michael T, Armstrong, Michaele J, Nicholson, Kristina J, Ohori, N Paul, Coyne, Christopher, Hodak, Steven P, Ferris, Robert L, LeBeau, Shane O, Nikiforov, Yuri E, Carty, Sally E

“…OBJECTIVES:To correlate thyroid cancer genotype with histology and outcomes. BACKGROUND:The prognostic significance of molecular signature in thyroid cancer…”
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