Search Results - "Ohoka, Yoshiharu"

GM-CSF and IL-4 synergistically trigger dendritic cells to acquire retinoic acid-producing capacity by Yokota, Aya, Takeuchi, Hajime, Maeda, Naoko, Ohoka, Yoshiharu, Kato, Chieko, Song, Si-Young, Iwata, Makoto

“…Retinoic acid (RA) produced by intestinal dendritic cells (DCs) imprints gut-homing specificity on lymphocytes and enhances Foxp3+ regulatory T-cell…”
Get full text

Cyp26b1 regulates retinoic acid-dependent signals in T cells and its expression is inhibited by transforming growth factor-β by Takeuchi, Hajime, Yokota, Aya, Ohoka, Yoshiharu, Iwata, Makoto

“…The vitamin A metabolite, retinoic acid (RA), plays important roles in the regulation of lymphocyte properties. Dendritic cells in gut-related lymphoid organs…”
Get full text

Retinoic acid-induced CCR9 expression requires transient TCR stimulation and cooperativity between NFATc2 and the retinoic acid receptor/retinoid X receptor complex by Ohoka, Yoshiharu, Yokota, Aya, Takeuchi, Hajime, Maeda, Naoko, Iwata, Makoto

“…Retinoic acid (RA) imprints gut-homing specificity on T cells upon activation by inducing the expression of chemokine receptor CCR9 and integrin α4β7. CCR9…”
Get full text

Retinoic acid and GM-CSF coordinately induce retinal dehydrogenase 2 (RALDH2) expression through cooperation between the RAR/RXR complex and Sp1 in dendritic cells by Ohoka, Yoshiharu, Yokota-Nakatsuma, Aya, Maeda, Naoko, Takeuchi, Hajime, Iwata, Makoto

“…Retinoic acid (RA)-producing dendritic cells (DCs) play critical roles in gut immunity. Retinal dehydrogenase 2 (RALDH2) encoded by Aldh1a2 is a key enzyme for…”
Get full text

Overcoming off-targets: assessing Western blot signals for Bcnt/Cfdp1, a tentative component of the chromatin remodeling complex by Iwashita, Shintaro, Suzuki, Takehiro, Kiriyama, Yoshimitsu, Dohmae, Naoshi, Ohoka, Yoshiharu, Song, Si-Young, Nakashima, Kentaro

“…The Bucentaur (BCNT) protein family is characterized by a conserved amino acid sequence at the C-terminus (BCNT-C domain) and plays an essential role in gene…”
Get full text

Physical and Functional Interactions of the Lysophosphatidic Acid Receptors with PDZ Domain-containing Rho Guanine Nucleotide Exchange Factors (RhoGEFs) by Yamada, Takeshi, Ohoka, Yoshiharu, Kogo, Mikihiko, Inagaki, Shinobu

“…Lysophosphatidic acid (LPA) is a serum-derived phospholipid that induces a variety of biological responses in various cells via heterotrimeric G…”
Get full text

Identification of a Negative Regulatory Region for the Exchange Activity and Characterization of T332I Mutant of Rho Guanine Nucleotide Exchange Factor 10 (ARHGEF10) by Chaya, Taro, Shibata, Satoshi, Tokuhara, Yasunori, Yamaguchi, Wataru, Matsumoto, Hiroshi, Kawahara, Ichiro, Kogo, Mikihiko, Ohoka, Yoshiharu, Inagaki, Shinobu

“…The T332I mutation in Rho guanine nucleotide exchange factor 10 (ARHGEF10) was previously found in persons with slowed nerve conduction velocities and thin…”
Get full text

A functional role for semaphorin 4D/plexin B1 interactions in epithelial branching morphogenesis during organogenesis by Korostylev, Alexander, Worzfeld, Thomas, Deng, Suhua, Friedel, Roland H, Swiercz, Jakub M, Vodrazka, Peter, Maier, Viola, Hirschberg, Alexandra, Ohoka, Yoshiharu, Inagaki, Shinobu, Offermanns, Stefan, Kuner, Rohini

“…Semaphorins and their receptors, plexins, carry out important functions during development and disease. In contrast to the well-characterized plexin A family,…”
Get full text

Isolation and characterization of cortactin isoforms and a novel cortactin‐binding protein, CBP90 by Ohoka, Yoshiharu, Takai, Yoshimi

“…Background Cortactin is a major phosphotyrosyl protein in pp60v–src‐transformed chicken embryo cells. Cortactin binds to actin filament (F‐actin) through a…”
Get full text

Sema4C, a Transmembrane Semaphorin, Interacts with a Post-synaptic Density Protein, PSD-95 by Inagaki, Shinobu, Ohoka, Yoshiharu, Sugimoto, Hisako, Fujioka, Shiho, Amazaki, Mayumi, Kurinami, Hitomi, Miyazaki, Nobuo, Tohyama, Masaya, Furuyama, Tatsuo

“…Semaphorins are known to act as chemorepulsive molecules that guide axons during neural development. Sema4C, a group 4 semaphorin, is a transmembrane…”
Get full text

Mouse Semaphorin H Induces PC12 Cell Neurite Outgrowth Activating Ras-Mitogen-activated Protein Kinase Signaling Pathway via Ca2+ Influx by Sakai, Takayoshi, Furuyama, Tatsuo, Ohoka, Yoshiharu, Miyazaki, Nobuo, Fujioka, Shi-ho, Sugimoto, Hisako, Amasaki, Mayumi, Hattori, Seisuke, Matsuya, Tokuzo, Inagaki, Shinobu

“…We recently showed that mouse semaphorin H (MSH), a secreted semaphorin molecule, acts as a chemorepulsive factor on sensory neurites. In this study, we found…”
Get full text

Retinoid X receptor agonists modulate Foxp3⁺ regulatory T cell and Th17 cell differentiation with differential dependence on retinoic acid receptor activation by Takeuchi, Hajime, Yokota-Nakatsuma, Aya, Ohoka, Yoshiharu, Kagechika, Hiroyuki, Kato, Chieko, Song, Si-Young, Iwata, Makoto

“…Retinoic acid (RA) enhances TGF-β-dependent differentiation of Foxp3(+) inducible regulatory T cells (iTregs) and inhibits Th17 differentiation by binding to…”
Get full text

In vitro differentiation and commitment of CD4+ CD8+ thymocytes to the CD4 lineage, without TCR engagement by Ohoka, Y, Kuwata, T, Tozawa, Y, Zhao, Y, Mukai, M, Motegi, Y, Suzuki, R, Yokoyama, M, Iwata, M

“…Thymocyte positive selection is based on protection of immature CD4/CD8 double-positive (DP) thymocytes from apoptosis and their differentiation into CD4 or…”
Get full text

Beta 1-integrin ligation and TLR ligation enhance GM-CSF–induced ALDH1A2 expression in dendritic cells, but differentially regulate their anti-inflammatory properties by Yokota-Nakatsuma, Aya, Ohoka, Yoshiharu, Takeuchi, Hajime, Song, Si-Young, Iwata, Makoto

“…Retinoic acid (RA)–producing CD103 + mature dendritic cells (DCs) in mesenteric lymph nodes (MLNs) play crucial roles in gut immunity. GM-CSF and RA contribute…”
Get full text

Efficient induction of CCR9 on T cells requires coactivation of retinoic acid receptors and retinoid X receptors (RXRs): exaggerated T Cell homing to the intestine by RXR activation with organotins by Takeuchi, Hajime, Yokota, Aya, Ohoka, Yoshiharu, Kagechika, Hiroyuki, Kato, Chieko, Song, Si-Young, Iwata, Makoto

“…The active vitamin A metabolite retinoic acid (RA) imprints gut-homing specificity on lymphocytes upon activation by inducing the expression of α4β7 integrin…”
Get full text

Retinoic Acid and GM-CSF Coordinately Induce Retinal Dehydrogenase 2 by Ohoka, Yoshiharu, Yokota-Nakatsuma, Aya, Maeda, Naoko, Takeuchi, Hajime, Iwata, Makoto

“…Retinoic acid (RA)-producing dendritic cells (DCs) play critical roles in gut immunity. Retinal dehydrogenase 2 (RALDH2) encoded by Aldh1a2 is a key enzyme for…”
Get full text

Cyp26b1 Regulates Retinoic Acid-Dependent Signals in T Cells and Its Expression Is Inhibited by Transforming Growth Factor-[beta] by Takeuchi, Hajime, Yokota, Aya, Ohoka, Yoshiharu, Iwata, Makoto

“…Background The vitamin A metabolite, retinoic acid (RA), plays important roles in the regulation of lymphocyte properties. Dendritic cells in gut-related…”
Get full text

In vitro differentiation and commitment of CD4+ thymocytes to the CD4+ lineage without TCR engagement by Ohoka, Yoshiharu, Kuwata, Takeshi, Tozawa, Yuzuru, Zhao, Yong, Mukai, Mutsumi, Motegi, Yoshiko, Suzuki, Rika, Yokoyama, Minesuke, Iwata, Makoto

“…Thymocyte positive selection is based on protection of immature CD4/CD8 double-positive (DP) thymocytes from apoptosis and their differentiation into CD4 or…”
Get full text

Purification and separation of closely related members of pertussis toxin-substrate G proteins by Katada, T, Kontani, K, Inanobe, A, Kobayashi, I, Ohoka, Y, Nishina, H, Takahashi, K

Get more information

Involvement of pertussis toxin-sensitive mechanism in retinoic acid-induced differentiation of human leukemic HL-60 cells by Ohoka, Y, Kontani, K, Iiri, T, Nishina, H, Katada, T

“…Retinoic acid-induced differentiation of human leukemic HL-60 cells is accompanied with the early induction of an ecto-enzyme of NAD+ glycohydrolase (NADase),…”
Get more information