Search Results - "Ohnstad, Hege O"

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    MDM2 antagonist Nutlin-3a potentiates antitumour activity of cytotoxic drugs in sarcoma cell lines by Ohnstad, Hege O, Paulsen, Erik B, Noordhuis, Paul, Berg, Marianne, Lothe, Ragnhild A, Vassilev, Lyubomir T, Myklebost, Ola

    Published in BMC cancer (30-05-2011)
    “…Frequent failure and severe side effects of current sarcoma therapy warrants new therapeutic approaches. The small-molecule MDM2 antagonist Nutlin-3a activates…”
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  3. 3

    LSAMP, a novel candidate tumor suppressor gene in human osteosarcomas, identified by array comparative genomic hybridization by Kresse, Stine H., Ohnstad, Hege O., Paulsen, Erik B., Bjerkehagen, Bodil, Szuhai, Karoly, Serra, Massimo, Schaefer, Karl‐Ludwig, Myklebost, Ola, Meza‐Zepeda, Leonardo A.

    Published in Genes chromosomes & cancer (01-08-2009)
    “…Osteosarcomas are the most common primary malignant tumor of bone, and almost all conventional osteosarcomas are high‐grade tumors with complex karyotypes. We…”
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    Array comparative genomic hybridization reveals distinct DNA copy number differences between gastrointestinal stromal tumors and leiomyosarcomas by MEZA-ZEPEDA, Leonardo A, KRESSE, Stine H, BARRAGAN-POLANIA, Ana H, BJERKEHAGEN, Bodil, OHNSTAD, Hege O, NAMLES, Heidi M, JUNBAI WANG, KRISTIANSEN, Bjørn E, MYKLEBOST, Ola

    Published in Cancer research (Chicago, Ill.) (15-09-2006)
    “…Leiomyosarcomas are spindle cell tumors showing smooth muscle differentiation. Until recently, most gastrointestinal stromal tumors (GIST) were also classified…”
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    Response to preoperative chemotherapy in patients undergoing resection of pulmonary metastasis from soft tissue sarcoma - a predictor of outcome? by Ohnstad, Hege O, Bruland, Oyvind S, Taksdal, Ingeborg, Bjerkehagen, Bodil, Nenadovic, Maja, Sæter, Gunnar, Jørgensen, Lars H, Hall, Kirsten Sundby

    Published in Acta oncologica (01-09-2014)
    “…Approximately 50% of patients with high-grade soft tissue sarcoma (STS) will develop pulmonary metastasis. This is the most frequent cause of death and…”
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    DNA copy number changes in human malignant fibrous histiocytomas by array comparative genomic hybridisation by Kresse, Stine H, Ohnstad, Hege O, Bjerkehagen, Bodil, Myklebost, Ola, Meza-Zepeda, Leonardo A

    Published in PloS one (09-11-2010)
    “…Malignant fibrous histiocytomas (MFHs), or undifferentiated pleomorphic sarcomas, are in general high-grade tumours with extensive chromosomal aberrations. In…”
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  7. 7

    DNA copy number changes in high-grade malignant peripheral nerve sheath tumors by array CGH by Kresse, Stine H, Skårn, Magne, Ohnstad, Hege O, Namløs, Heidi M, Bjerkehagen, Bodil, Myklebost, Ola, Meza-Zepeda, Leonardo A

    Published in Molecular cancer (03-06-2008)
    “…Malignant peripheral nerve sheath tumors (MPNSTs) are rare and highly aggressive soft tissue tumors showing complex chromosomal aberrations. In order to…”
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    Correlation of TP53 and MDM2 genotypes with response to therapy in sarcoma by Ohnstad, Hege O., Castro, Russell, Sun, Jinchang, Heintz, Karen‐Marie, Vassilev, Lyubomir T., Bjerkehagen, Bodil, Kresse, Stine H., Meza‐Zepeda, Leonardo A., Myklebost, Ola

    Published in Cancer (01-03-2013)
    “…BACKGROUND: Relatively few sarcomas harbor TP53 (tumor protein p53) mutations, but in many cases, amplification of MDM2 (murine double minute 2) effectively…”
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