Search Results - "Ohnstad, Hege O"
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Prognostic value of PAM50 and risk of recurrence score in patients with early-stage breast cancer with long-term follow-up
Published in Breast cancer research : BCR (14-11-2017)“…The aim of this study was to investigate the prognostic value of the PAM50 intrinsic subtypes and risk of recurrence (ROR) score in patients with early breast…”
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MDM2 antagonist Nutlin-3a potentiates antitumour activity of cytotoxic drugs in sarcoma cell lines
Published in BMC cancer (30-05-2011)“…Frequent failure and severe side effects of current sarcoma therapy warrants new therapeutic approaches. The small-molecule MDM2 antagonist Nutlin-3a activates…”
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LSAMP, a novel candidate tumor suppressor gene in human osteosarcomas, identified by array comparative genomic hybridization
Published in Genes chromosomes & cancer (01-08-2009)“…Osteosarcomas are the most common primary malignant tumor of bone, and almost all conventional osteosarcomas are high‐grade tumors with complex karyotypes. We…”
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Array comparative genomic hybridization reveals distinct DNA copy number differences between gastrointestinal stromal tumors and leiomyosarcomas
Published in Cancer research (Chicago, Ill.) (15-09-2006)“…Leiomyosarcomas are spindle cell tumors showing smooth muscle differentiation. Until recently, most gastrointestinal stromal tumors (GIST) were also classified…”
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Response to preoperative chemotherapy in patients undergoing resection of pulmonary metastasis from soft tissue sarcoma - a predictor of outcome?
Published in Acta oncologica (01-09-2014)“…Approximately 50% of patients with high-grade soft tissue sarcoma (STS) will develop pulmonary metastasis. This is the most frequent cause of death and…”
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DNA copy number changes in human malignant fibrous histiocytomas by array comparative genomic hybridisation
Published in PloS one (09-11-2010)“…Malignant fibrous histiocytomas (MFHs), or undifferentiated pleomorphic sarcomas, are in general high-grade tumours with extensive chromosomal aberrations. In…”
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DNA copy number changes in high-grade malignant peripheral nerve sheath tumors by array CGH
Published in Molecular cancer (03-06-2008)“…Malignant peripheral nerve sheath tumors (MPNSTs) are rare and highly aggressive soft tissue tumors showing complex chromosomal aberrations. In order to…”
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Correlation of TP53 and MDM2 genotypes with response to therapy in sarcoma
Published in Cancer (01-03-2013)“…BACKGROUND: Relatively few sarcomas harbor TP53 (tumor protein p53) mutations, but in many cases, amplification of MDM2 (murine double minute 2) effectively…”
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