Search Results - "Ohno, Tsunehisa"
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Histologic Characterization of Human Scarred Vocal Folds
Published in Journal of voice (01-07-2009)“…Summary Vocal fold scarring remains a significant problem. Although several animal models have been developed to improve our understanding of the…”
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Age-Associated Changes in the Expression and Deposition of Vocal Fold Collagen and Hyaluronan
Published in Annals of otology, rhinology & laryngology (01-10-2009)“…Objectives: We investigated age-associated changes in the expression and deposition of collagen and hyaluronan (hyaluronic acid; HA) in aged vocal folds…”
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Journal Article Conference Proceeding -
3
Gene expression of transforming growth factor-β1 and hepatocyte growth factor during wound healing of injured rat vocal fold
Published in The Laryngoscope (01-04-2009)“…Objectives/Hypothesis: To investigate the expression of genes coding transforming growth factor (TGF)‐β1, hepatocyte growth factor (HGF), and c‐Met, its…”
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Effects of raised-intensity phonation on inflammatory mediator gene expression in normal rabbit vocal fold
Published in Otolaryngology-head and neck surgery (01-10-2010)“…To investigate the hypothesis that a transient episode of raised-intensity phonation causes a significant increase in vocal fold inflammatory messenger RNA…”
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Topical morphine gel for pain management in head and neck cancer patients
Published in Auris, nasus, larynx (01-10-2014)“…Abstract Pain is common in head and neck cancer patients. Regardless of the cause, pain management is essential in supportive care. Recent research has…”
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Model of Evoked Rabbit Phonation
Published in Annals of otology, rhinology & laryngology (01-01-2009)“…Objectives: We describe a method for eliciting phonation in an in vivo rabbit preparation using low-frequency, bipolar pulsed stimulation of the cricothyroid…”
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Characterization of raised phonation in an evoked rabbit phonation model
Published in The Laryngoscope (01-07-2009)“…Objectives/Hypothesis: Our laboratory has developed an in vivo rabbit model to investigate the effects of phonation on expression and turnover of the vocal…”
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Journal Article Conference Proceeding -
8
Regenerative Effects of Basic Fibroblast Growth Factor on Extracellular Matrix Production in Aged Rat Vocal Folds
Published in Annals of otology, rhinology & laryngology (01-08-2009)“…Objectives We investigated acute changes in extracellular matrix (ECM) gene expression and histologic changes in the deposition of collagen and hyaluronan…”
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Extracellular Matrix Gene Expression after Vocal Fold Injury in a Rabbit Model
Published in Annals of otology, rhinology & laryngology (01-08-2008)“…Objectives: We determined the expression of matrix metalloproteinase (MMP)–1, MMP-9, collagen types I and III, and fibronectin from rabbit vocal folds after…”
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Regeneration of aged rat vocal folds using hepatocyte growth factor therapy
Published in The Laryngoscope (01-07-2009)“…Objectives/Hypothesis: We investigated acute changes in extracellular matrix gene expression and histologic changes in the deposition of collagen and…”
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Journal Article Conference Proceeding -
11
Drug Delivery System of Hepatocyte Growth Factor for the Treatment of Vocal Fold Scarring in a Canine Model
Published in Annals of otology, rhinology & laryngology (01-10-2007)“…Objectives: Vocal fold scarring remains a therapeutic challenge. Previous studies have indicated that hepatocyte growth factor (HGF), a strong antifibrotic…”
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12
The potential use of bone marrow stromal cells for cochlear cell therapy
Published in Neuroreport (05-03-2007)“…This study investigated the potential of bone-marrow stromal cell transplantation for cell replacement therapy in the cochlea. Bone-marrow stromal cells…”
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13
Effect of Hepatocyte Growth Factor on Gene Expression of Extracellular Matrix during Wound Healing of the Injured Rat Vocal Fold
Published in Annals of otology, rhinology & laryngology (01-09-2008)“…Objectives: We performed a prospective, sham-controlled animal study to investigate the effects of hepatocyte growth factor (HGF) manipulation of the…”
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14
Perioperative management of thyroid surgery in patients treated with drug-eluting stents
Published in Nippon Jibi Inkoka Gakkai Kaiho (01-08-2014)“…The use of drug-eluting stents (DES) has been spreading worldwide to treat coronary heart disease. Patients treated with DES need long-term dual antiplatelet…”
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Expression of extracellular matrix proteins in the vocal folds and bone marrow derived stromal cells of rats
Published in European archives of oto-rhino-laryngology (01-06-2008)“…Vocal fold scarring remains a therapeutic challenge. Our research group has indicated that bone marrow-derived stromal cells (BSCs) may have therapeutic…”
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Treatment of aging vocal folds: novel approaches
Published in Current opinion in otolaryngology & head and neck surgery (01-12-2014)“…This article aims to review previous research reports and to summarize current strategies for the treatment of the aging vocal fold using regenerative medicine…”
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Extracellular matrix gene expression during wound healing of the injured rat vocal fold
Published in Otolaryngology-head and neck surgery (01-05-2009)“…To measure the expression of procollagen-I and -III, decorin, and hyaluronan synthase (HAS)-1, -2, and -3 during the inflammatory, proliferative, and…”
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R432 – Gene Expression of the Remodeling Rat Vocal Fold Wound
Published in Otolaryngology-head and neck surgery (01-08-2008)“…Problem The authors investigated the expression of key extracellular matrix genes after vocal fold wounding in a rat model to better understand the reparative…”
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Engraftment of embryonic stem cell-derived neurons into the cochlear modiolus
Published in Neuroreport (28-11-2005)“…This study aimed to evaluate the potential of embryonic stem cell-derived neural progenitors for use as transplants for the replacement of the auditory primary…”
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