Search Results - "Ohno, Tsunehisa"

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  1. 1

    Histologic Characterization of Human Scarred Vocal Folds by Hirano, Shigeru, Minamiguchi, Sachiko, Yamashita, Masaru, Ohno, Tsunehisa, Kanemaru, Shin-ichi, Kitamura, Morimasa

    Published in Journal of voice (01-07-2009)
    “…Summary Vocal fold scarring remains a significant problem. Although several animal models have been developed to improve our understanding of the…”
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    Journal Article
  2. 2

    Age-Associated Changes in the Expression and Deposition of Vocal Fold Collagen and Hyaluronan by Ohno, Tsunehisa, Hirano, Shigeru, Rousseau, Bernard

    Published in Annals of otology, rhinology & laryngology (01-10-2009)
    “…Objectives: We investigated age-associated changes in the expression and deposition of collagen and hyaluronan (hyaluronic acid; HA) in aged vocal folds…”
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    Journal Article Conference Proceeding
  3. 3

    Gene expression of transforming growth factor-β1 and hepatocyte growth factor during wound healing of injured rat vocal fold by Ohno, Tsunehisa, Hirano, Shigeru, Rousseau, Bernard

    Published in The Laryngoscope (01-04-2009)
    “…Objectives/Hypothesis: To investigate the expression of genes coding transforming growth factor (TGF)‐β1, hepatocyte growth factor (HGF), and c‐Met, its…”
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    Journal Article
  4. 4

    Effects of raised-intensity phonation on inflammatory mediator gene expression in normal rabbit vocal fold by Swanson, Erik R., Ohno, Tsunehisa, Abdollahian, Dave, Garrett, C. Gaelyn, Rousseau, Bernard

    Published in Otolaryngology-head and neck surgery (01-10-2010)
    “…To investigate the hypothesis that a transient episode of raised-intensity phonation causes a significant increase in vocal fold inflammatory messenger RNA…”
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    Journal Article
  5. 5

    Topical morphine gel for pain management in head and neck cancer patients by Miyazaki, Takuya, Satou, Shinichi, Ohno, Tsunehisa, Yoshida, Atsuhiro, Nishimura, Kazunari

    Published in Auris, nasus, larynx (01-10-2014)
    “…Abstract Pain is common in head and neck cancer patients. Regardless of the cause, pain management is essential in supportive care. Recent research has…”
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    Journal Article
  6. 6

    Model of Evoked Rabbit Phonation by Ge, Ping Jiang, French, Lesley C., Ohno, Tsunehisa, Zealear, David L., Rousseau, Bernard

    Published in Annals of otology, rhinology & laryngology (01-01-2009)
    “…Objectives: We describe a method for eliciting phonation in an in vivo rabbit preparation using low-frequency, bipolar pulsed stimulation of the cricothyroid…”
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    Journal Article
  7. 7

    Characterization of raised phonation in an evoked rabbit phonation model by Swanson, Erik R., Abdollahian, Davood, Ohno, Tsunehisa, Ge, Pingjiang, Zealear, David L., Rousseau, Bernard

    Published in The Laryngoscope (01-07-2009)
    “…Objectives/Hypothesis: Our laboratory has developed an in vivo rabbit model to investigate the effects of phonation on expression and turnover of the vocal…”
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    Journal Article Conference Proceeding
  8. 8

    Regenerative Effects of Basic Fibroblast Growth Factor on Extracellular Matrix Production in Aged Rat Vocal Folds by Ohno, Tsunehisa, Yoo, Mi Jin, Swanson, Erik R., Hirano, Shigeru, Ossoff, Robert H., Rousseau, Bernard

    Published in Annals of otology, rhinology & laryngology (01-08-2009)
    “…Objectives We investigated acute changes in extracellular matrix (ECM) gene expression and histologic changes in the deposition of collagen and hyaluronan…”
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    Journal Article
  9. 9

    Extracellular Matrix Gene Expression after Vocal Fold Injury in a Rabbit Model by Rousseau, Bernard, Ge, Ping Jiang, Ohno, Tsunehisa, French, Lesley C., Thibeault, Susan L.

    Published in Annals of otology, rhinology & laryngology (01-08-2008)
    “…Objectives: We determined the expression of matrix metalloproteinase (MMP)–1, MMP-9, collagen types I and III, and fibronectin from rabbit vocal folds after…”
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    Journal Article
  10. 10

    Regeneration of aged rat vocal folds using hepatocyte growth factor therapy by Ohno, Tsunehisa, Yoo, Mi Jin, Swanson, Erik R., Hirano, Shigeru, Ossoff, Robert H., Rousseau, Bernard

    Published in The Laryngoscope (01-07-2009)
    “…Objectives/Hypothesis: We investigated acute changes in extracellular matrix gene expression and histologic changes in the deposition of collagen and…”
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    Journal Article Conference Proceeding
  11. 11

    Drug Delivery System of Hepatocyte Growth Factor for the Treatment of Vocal Fold Scarring in a Canine Model by Ohno, Tsunehisa, Hirano, Shigeru, Kanemaru, Shin-Ichi, Yamashita, Masaru, Umeda, Hiroo, Suehiro, Atsushi, Tamura, Yoshihiro, Nakamura, Tatsuo, Ito, Juichi, Tabata, Yasuhiko

    Published in Annals of otology, rhinology & laryngology (01-10-2007)
    “…Objectives: Vocal fold scarring remains a therapeutic challenge. Previous studies have indicated that hepatocyte growth factor (HGF), a strong antifibrotic…”
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    Journal Article
  12. 12

    The potential use of bone marrow stromal cells for cochlear cell therapy by Sharif, Sadia, Nakagawa, Takayuki, Ohno, Tsunehisa, Matsumoto, Masahiro, Kita, Tomoko, Riazuddin, Sheikh, Ito, Juichi

    Published in Neuroreport (05-03-2007)
    “…This study investigated the potential of bone-marrow stromal cell transplantation for cell replacement therapy in the cochlea. Bone-marrow stromal cells…”
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    Journal Article
  13. 13

    Effect of Hepatocyte Growth Factor on Gene Expression of Extracellular Matrix during Wound Healing of the Injured Rat Vocal Fold by Ohno, Tsunehisa, French, Lesley C., Hirano, Shigeru, Ossoff, Robert H., Rousseau, Bernard

    Published in Annals of otology, rhinology & laryngology (01-09-2008)
    “…Objectives: We performed a prospective, sham-controlled animal study to investigate the effects of hepatocyte growth factor (HGF) manipulation of the…”
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    Journal Article
  14. 14

    Perioperative management of thyroid surgery in patients treated with drug-eluting stents by Ohno, Tsunehisa, Mizukoshi, Akifumi, Kimura, Toshiya, Tamaki, Hisanobu

    Published in Nippon Jibi Inkoka Gakkai Kaiho (01-08-2014)
    “…The use of drug-eluting stents (DES) has been spreading worldwide to treat coronary heart disease. Patients treated with DES need long-term dual antiplatelet…”
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    Journal Article
  15. 15

    Expression of extracellular matrix proteins in the vocal folds and bone marrow derived stromal cells of rats by Ohno, Tsunehisa, Hirano, Shigeru, Kanemaru, Shin-ichi, Yamashita, Masaru, Umeda, Hiroo, Suehiro, Atsushi, Nakamura, Tatsuo, Ito, Juichi

    Published in European archives of oto-rhino-laryngology (01-06-2008)
    “…Vocal fold scarring remains a therapeutic challenge. Our research group has indicated that bone marrow-derived stromal cells (BSCs) may have therapeutic…”
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    Journal Article
  16. 16

    Treatment of aging vocal folds: novel approaches by Ohno, Tsunehisa, Hirano, Shigeru

    “…This article aims to review previous research reports and to summarize current strategies for the treatment of the aging vocal fold using regenerative medicine…”
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    Journal Article
  17. 17

    Extracellular matrix gene expression during wound healing of the injured rat vocal fold by Ohno, Tsunehisa, Hirano, Shigeru, Rousseau, Bernard

    Published in Otolaryngology-head and neck surgery (01-05-2009)
    “…To measure the expression of procollagen-I and -III, decorin, and hyaluronan synthase (HAS)-1, -2, and -3 during the inflammatory, proliferative, and…”
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    Journal Article
  18. 18
  19. 19

    R432 – Gene Expression of the Remodeling Rat Vocal Fold Wound by Ohno, Tsunehisa, French, Lesley C., Rousseau, Bernard

    Published in Otolaryngology-head and neck surgery (01-08-2008)
    “…Problem The authors investigated the expression of key extracellular matrix genes after vocal fold wounding in a rat model to better understand the reparative…”
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    Journal Article
  20. 20

    Engraftment of embryonic stem cell-derived neurons into the cochlear modiolus by Okano, Takayuki, Nakagawa, Takayuki, Endo, Tsuyoshi, Kim, Tae-Soo, Kita, Tomoko, Tamura, Tetsuya, Matsumoto, Masahiro, Ohno, Tsunehisa, Sakamoto, Tatsunori, Iguchi, Fukuichiro, Ito, Juichi

    Published in Neuroreport (28-11-2005)
    “…This study aimed to evaluate the potential of embryonic stem cell-derived neural progenitors for use as transplants for the replacement of the auditory primary…”
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