Search Results - "Ohno, Shigeaki"

Pathogenesis of Non-Infectious Uveitis Elucidated by Recent Genetic Findings by Takeuchi, Masaki, Mizuki, Nobuhisa, Ohno, Shigeaki

“…Uveitis is a generic term for inflammation of the uvea, which includes the iris, ciliary body, and choroid. Prevalence of underlying non-infectious uveitis…”
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Japanese guidelines for allergic conjunctival diseases 2020 by Miyazaki, Dai, Takamura, Etsuko, Uchio, Eiichi, Ebihara, Nobuyuki, Ohno, Shigeaki, Ohashi, Yuichi, Okamoto, Shigeki, Satake, Yoshiyuki, Shoji, Jun, Namba, Kenichi, Fukagawa, Kazumi, Fukushima, Atsuki, Fujishima, Hiroshi

“…The definition, classification, pathogenesis, test methods, clinical findings, criteria for diagnosis, and therapies of allergic conjunctival disease are…”
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Japanese guidelines for allergic conjunctival diseases 2017 by Takamura, Etsuko, Uchio, Eiichi, Ebihara, Nobuyuki, Ohno, Shigeaki, Ohashi, Yuichi, Okamoto, Shigeki, Kumagai, Naoki, Satake, Yoshiyuki, Shoji, Jun, Nakagawa, Yayoi, Namba, Kenichi, Fukagawa, Kazumi, Fukushima, Atsuki, Fujishima, Hiroshi

“…The definition, classification, pathogenesis, test methods, clinical findings, criteria for diagnosis, and therapies of allergic conjunctival disease are…”
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Treatment of Behçet's Disease: An Algorithmic Multidisciplinary Approach by Alpsoy, Erkan, Leccese, Pietro, Emmi, Giacomo, Ohno, Shigeaki

“…Behçet's disease (BD) is a chronic, relapsing inflammatory, multisystem disease of unknown etiology. The disease has a wide clinical spectrum of mucocutaneous…”
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Editorial: New Insights Into Uveitis: Immunity, Genes, and Microbes by Yang, Peizeng, Ohno, Shigeaki, Zierhut, Manfred

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Intravitreal Sirolimus for Noninfectious Uveitis: A Phase III Sirolimus Study Assessing Double-masKed Uveitis TReAtment (SAKURA) by Nguyen, Quan Dong, MD, MSc, Merrill, Pauline T., MD, Clark, W. Lloyd, MD, Banker, Alay S., MD, Fardeau, Christine, MD, Franco, Pablo, MD, LeHoang, Phuc, MD, PhD, Ohno, Shigeaki, MD, PhD, Rathinam, Sivakumar R., FAMS, PhD, Thurau, Stephan, MD, FEBO, Abraham, Abu, MD, Wilson, Laura, MD, Yang, Yang, PhD, Shams, Naveed, MD, PhD

“…Purpose To evaluate the efficacy and safety of intravitreal sirolimus in the treatment of noninfectious uveitis (NIU) of the posterior segment (i.e.,…”
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Executive summary : Japanese guidelines for allergic conjunctival diseases 2021 by Miyazaki, Dai, Fukushima, Atsuki, Uchio, Eiichi, Shoji, Jun, Namba, Kenichi, Ebihara, Nobuyuki, Takamura, Etsuko, Fukuda, Ken, Matsuda, Akira, Okamoto, Shigeki, Fukagawa, Kazumi, Fujishima, Hiroshi, Ohno, Shigeaki, Ohashi, Yuichi

“…[ABSTRACT] Allergic conjunctival disease (ACD) is an inflammatory disease of the conjunctiva that is mainly caused by type I hypersensitivity response to…”
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Clinical features of ocular sarcoidosis: severe, refractory, and prolonged inflammation by Suzuki, Kayo, Ishihara, Mami, Namba, Kenichi, Ohno, Shigeaki, Goto, Hiroshi, Takase, Hiroshi, Kawano, Shigeru, Shibuya, Etsuko, Hase, Keitaro, Iwata, Daiju, Mizuuchi, Kazuomi, Kitaichi, Nobuyoshi, Mizuki, Nobuhisa, Ishida, Susumu

“…Purpose To clarify the proportion of ocular sarcoidosis with severe, refractory, and prolonged inflammation and their association with ocular complications and…”
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Safety and efficacy of infliximab in the treatment of refractory uveoretinitis in Behçet's disease: a large-scale, long-term postmarketing surveillance in Japan by Ohno, Shigeaki, Umebayashi, Itsuro, Matsukawa, Miyuki, Goto, Takashi, Yano, Toshiro

“…Infliximab, an anti-tumor necrosis factor-alpha antibody, has been reported to have excellent efficacy for refractory uveoretinitis in Behçet's disease (RUBD),…”
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Genome-wide association studies identify IL23R - IL12RB2 and IL10 as Behçet's disease susceptibility loci by Mizuki, Nobuhisa, Inoko, Hidetoshi, Meguro, Akira, Ota, Masao, Ohno, Shigeaki, Shiota, Tomoko, Kawagoe, Tatsukata, Ito, Norihiko, Kera, Jiro, Okada, Eiichi, Yatsu, Keisuke, Song, Yeong-Wook, Lee, Eun-Bong, Kitaichi, Nobuyoshi, Namba, Kenichi, Horie, Yukihiro, Takeno, Mitsuhiro, Sugita, Sunao, Mochizuki, Manabu, Bahram, Seiamak, Ishigatsubo, Yoshiaki

“…Behçet's disease is a chronic systemic inflammatory disorder characterized by four major manifestations: recurrent ocular symptoms, oral and genital ulcers and…”
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Identification of a susceptibility locus in STAT4 for Behçet's disease in Han Chinese in a genome-wide association study by Hou, Shengping, Yang, Zhenglin, Du, Liping, Jiang, Zhengxuan, Shu, Qinmeng, Chen, Yuanyuan, Li, Fuzhen, Zhou, Qingyun, Ohno, Shigeaki, Chen, Rui, Kijlstra, Aize, Rosenbaum, James T., Yang, Peizeng

“…Objective To identify susceptibility loci for Behçet's disease (BD) and elucidate their functional role. Methods A genome‐wide association study (GWAS) and…”
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Clinical features of Behcet’s disease in Mongolia: a multicenter study by Balt, Javzandulam, Jamyanjav, Baasankhuu, Jav, Sarantuya, Dandii, Zulgerel, Ganbold, Chimedlkhamsuren, Horie, Yukihiro, Lennikov, Anton, Uehara, Osamu, Ohno, Shigeaki, Kitaichi, Nobuyoshi

“…Objective The aim of the present study is to investigate the clinical features of patients with Behcet’s disease (BD) in Mongolia. Methods Patients were…”
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Comprehensive analysis of the association between UBAC2 polymorphisms and Behçet’s disease in a Japanese population by Yamazoe, Kyoko, Meguro, Akira, Takeuchi, Masaki, Shibuya, Etsuko, Ohno, Shigeaki, Mizuki, Nobuhisa

“…Behçet’s disease (BD) is reportedly associated with polymorphisms of the ubiquitin-associated domain containing 2 ( UBAC2 ) gene in Turkish, Italian, and…”
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Identification of Novel Risk Loci for Behçet's Disease–Related Uveitis in a Chinese Population in a Genome‐Wide Association Study by Su, Guannan, Zhong, Zhenyu, Zhou, Qingyun, Du, Liping, Ye, Zi, Li, Fuzhen, Zhuang, Wenjuan, Wang, Chaokui, Liang, Liang, Ji, Yan, Cao, Qingfeng, Wang, Qingfeng, Chang, Rui, Tan, Handan, Yi, Shenglan, Li, Yujing, Feng, Xiaojie, Liao, Weiting, Zhang, Wanyun, Shu, Jia, Tan, Shiyao, Xu, Jing, Pan, Su, Li, Hongxi, Shi, Jing, Chen, Zhijun, Zhu, Ying, Ye, Xingsheng, Tan, Xiao, Zhang, Jun, Liu, Zhangluxi, Huang, Fanfan, Yuan, Gangxiang, Pang, Tingting, Liu, Yizong, Ding, Jiadong, Gao, Yingnan, Zhang, Meifen, Chi, Wei, Liu, Xiaoli, Wang, Yuqin, Chen, Ling, Meguro, Akira, Takeuchi, Masaki, Mizuki, Nobuhisa, Ohno, Shigeaki, Zuo, Xianbo, Kijlstra, Aize, Yang, Peizeng

“…Objective To explore susceptibility loci associated with uveitis in Behçet's disease (BD). Methods We conducted a 2‐stage study, consisting of a genome‐wide…”
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Genome-wide association study identifies GIMAP as a novel susceptibility locus for Behcet's disease by Lee, Yun Jong, Horie, Yukihiro, Wallace, Graham R, Choi, Yong Seok, Park, Ji Ah, Choi, Ji Yong, Song, Ran, Kang, Young-Mo, Kang, Seong Wook, Baek, Han Joo, Kitaichi, Nobuyoshi, Meguro, Akira, Mizuki, Nobuhisa, Namba, Kenichi, Ishida, Susumu, Kim, Jinhyun, Niemczyk, Edyta, Lee, Eun Young, Song, Yeong Wook, Ohno, Shigeaki, Lee, Eun Bong

“…To identify non-major histocompatibility complex susceptible genes that might contribute to Behçet's disease (BD). We performed a genome-wide association study…”
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Involvement of IL-32 in activation-induced cell death in T cells by Goda, Chiho, Kanaji, Taisuke, Kanaji, Sachiko, Tanaka, Go, Arima, Kazuhiko, Ohno, Shigeaki, Izuhara, Kenji

“…NK cell transcript 4 (NK4), now denoted as IL-32, was originally identified as a transcript whose expression was increased in activated NK cells. It has been…”
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Disinfectant potential in inactivation of epidemic keratoconjunctivitis-related adenoviruses by potassium peroxymonosulfate by Hashizume, Mei, Aoki, Koki, Ohno, Shigeaki, Kitaichi, Nobuyoshi, Yawata, Nobuyo, Gonzalez, Gabriel, Nonaka, Hirotaka, Sato, Seiichi, Takaoka, Akinori

“…Purpose: The aim of this study was to test the antiviral effectivity of potassium peroxymonosulfate (RUBYSTA®, KYORIN) against five epidemic…”
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Efficacy and Safety of Intravitreal Sirolimus for Noninfectious Uveitis of the Posterior Segment by Merrill, Pauline T., Clark, W. Lloyd, Banker, Alay S., Fardeau, Christine, Franco, Pablo, LeHoang, Phuc, Ohno, Shigeaki, Rathinam, Sivakumar R., Ali, Yusuf, Mudumba, Sri, Shams, Naveed, Nguyen, Quan Dong

“…To evaluate the efficacy and safety of intravitreal sirolimus in the management of noninfectious uveitis of the posterior segment (NIU-PS). Combined analysis…”
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Variants in IL23R-C1orf141 and ADO-ZNF365-EGR2 are associated with susceptibility to Vogt-Koyanagi-Harada disease in Japanese population by Sakono, Takuto, Meguro, Akira, Takeuchi, Masaki, Yamane, Takahiro, Teshigawara, Takeshi, Kitaichi, Nobuyoshi, Horie, Yukihiro, Namba, Kenichi, Ohno, Shigeaki, Nakao, Kumiko, Sakamoto, Taiji, Sakai, Tsutomu, Nakano, Tadashi, Keino, Hiroshi, Okada, Annabelle A, Takeda, Atsunobu, Ito, Takako, Mashimo, Hisashi, Ohguro, Nobuyuki, Oono, Shinichirou, Enaida, Hiroshi, Okinami, Satoshi, Horita, Nobuyuki, Ota, Masao, Mizuki, Nobuhisa

“…Vogt-Koyanagi-Harada (VKH) disease is a systemic inflammatory disorder that affects pigment cell-containing organs such as the eye (e.g., chronic and/or…”
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Novel Human Adenovirus Causing Nosocomial Epidemic Keratoconjunctivitis by Ishiko, Hiroaki, Shimada, Yasushi, Konno, Tsunetada, Hayashi, Akio, Ohguchi, Takeshi, Tagawa, Yoshitsugu, Aoki, Koki, Ohno, Shigeaki, Yamazaki, Shudo

“…In 2000, we encountered cases of nosocomial infections with epidemic keratoconjunctivitis (EKC) at a university hospital in Kobe, in the western part of Japan…”
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