Search Results - "Ohno, Seiko"

The genetic background of arrhythmogenic right ventricular cardiomyopathy by Ohno, Seiko, MD, PhD

“…Abstract Arrhythmogenic right ventricular cardiomyopathy (ARVC) is characterized by degeneration of the right ventricle and ventricular tachycardia originating…”
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How Should We Treat School-Aged Children With Borderline QT Prolongation? by Ohno, Seiko

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European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) Expert Consensus Statement on the state of genetic testing for cardiac diseases by Wilde, Arthur A M, Semsarian, Christopher, Márquez, Manlio F, Shamloo, Alireza Sepehri, Ackerman, Michael J, Ashley, Euan A, Sternick, Eduardo Back, Barajas-Martinez, Héctor, Behr, Elijah R, Bezzina, Connie R, Breckpot, Jeroen, Charron, Philippe, Chockalingam, Priya, Crotti, Lia, Gollob, Michael H, Lubitz, Steven, Makita, Naomasa, Ohno, Seiko, Ortiz-Genga, Martín, Sacilotto, Luciana, Schulze-Bahr, Eric, Shimizu, Wataru, Sotoodehnia, Nona, Tadros, Rafik, Ware, James S, Winlaw, David S, Kaufman, Elizabeth S, Aiba, Takeshi, Bollmann, Andreas, Choi, Jong Il, Dalal, Aarti, Darrieux, Francisco, Giudicessi, John, Guerchicoff, Mariana, Hong, Kui, Krahn, Andrew D, MacIntyre, Ciorsti, Mackall, Judith A, Mont, Lluís, Napolitano, Carlo, Ochoa, Juan Pablo, Peichl, Petr, Pereira, Alexandre C, Schwartz, Peter J, Skinner, Jon, Stellbrink, Christoph, Tfelt-Hansen, Jacob, Deneke, Thomas

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Transcriptional cofactor Vgll2 is required for functional adaptations of skeletal muscle induced by chronic overload by Honda, Masahiko, Tsuchimochi, Hirotsugu, Hitachi, Keisuke, Ohno, Seiko

“…Skeletal muscle is composed of heterogeneous populations of myofibers classified as slow‐ and fast‐twitch fibers. Myofiber size and composition are drastically…”
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Correction: Gender Differences in the Inheritance Mode of RYR2 Mutations in Catecholaminergic Polymorphic Ventricular Tachycardia Patients by Ohno, Seiko, Hasegawa, Kanae, Horie, Minoru

“…[This corrects the article DOI: 10.1371/journal.pone.0131517.]…”
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European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) Expert Consensus Statement on the State of Genetic Testing for Cardiac Diseases by Wilde, Arthur A.M., Semsarian, Christopher, Márquez, Manlio F., Sepehri Shamloo, Alireza, Ackerman, Michael J., Ashley, Euan A., Sternick, Eduardo Back, Barajas-Martinez, Héctor, Behr, Elijah R., Bezzina, Connie R., Breckpot, Jeroen, Charron, Philippe, Chockalingam, Priya, Crotti, Lia, Gollob, Michael H., Lubitz, Steven, Makita, Naomasa, Ohno, Seiko, Ortiz-Genga, Martín, Sacilotto, Luciana, Schulze-Bahr, Eric, Shimizu, Wataru, Sotoodehnia, Nona, Tadros, Rafik, Ware, James S., Winlaw, David S., Kaufman, Elizabeth S., Aiba, Takeshi, Bollmann, Andreas, Choi, Jong-Il, Dalal, Aarti, Darrieux, Francisco, Giudicessi, John, Guerchicoff, Mariana, Hong, Kui, Krahn, Andrew D., MacIntyre, Ciorsti, Mackall, Judith A., Mont, Lluís, Napolitano, Carlo, Ochoa, Juan Pablo, Peichl, Petr, Pereira, Alexandre C., Schwartz, Peter J., Skinner, Jon, Stellbrink, Christoph, Tfelt-Hansen, Jacob, Deneke, Thomas

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Calmodulin mutations and life-threatening cardiac arrhythmias: insights from the International Calmodulinopathy Registry by Crotti, Lia, Spazzolini, Carla, Tester, David J, Ghidoni, Alice, Baruteau, Alban-Elouen, Beckmann, Britt-Maria, Behr, Elijah R, Bennett, Jeffrey S, Bezzina, Connie R, Bhuiyan, Zahurul A, Celiker, Alpay, Cerrone, Marina, Dagradi, Federica, De Ferrari, Gaetano M, Etheridge, Susan P, Fatah, Meena, Garcia-Pavia, Pablo, Al-Ghamdi, Saleh, Hamilton, Robert M, Al-Hassnan, Zuhair N, Horie, Minoru, Jimenez-Jaimez, Juan, Kanter, Ronald J, Kaski, Juan P, Kotta, Maria-Christina, Lahrouchi, Najim, Makita, Naomasa, Norrish, Gabrielle, Odland, Hans H, Ohno, Seiko, Papagiannis, John, Parati, Gianfranco, Sekarski, Nicole, Tveten, Kristian, Vatta, Matteo, Webster, Gregory, Wilde, Arthur A M, Wojciak, Julianne, George, Alfred L, Ackerman, Michael J, Schwartz, Peter J

“…Abstract Aims Calmodulinopathies are rare life-threatening arrhythmia syndromes which affect mostly young individuals and are, caused by mutations in any of…”
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Gender Differences in the Inheritance Mode of RYR2 Mutations in Catecholaminergic Polymorphic Ventricular Tachycardia Patients by Ohno, Seiko, Hasegawa, Kanae, Horie, Minoru

“…Catecholaminergic polymorphic ventricular tachycardia (CPVT) is one of the causes of sudden cardiac death in young people and results from RYR2 mutations in…”
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The genetics underlying acquired long QT syndrome: impact for genetic screening by Itoh, Hideki, Crotti, Lia, Aiba, Takeshi, Spazzolini, Carla, Denjoy, Isabelle, Fressart, Véronique, Hayashi, Kenshi, Nakajima, Tadashi, Ohno, Seiko, Makiyama, Takeru, Wu, Jie, Hasegawa, Kanae, Mastantuono, Elisa, Dagradi, Federica, Pedrazzini, Matteo, Yamagishi, Masakazu, Berthet, Myriam, Murakami, Yoshitaka, Shimizu, Wataru, Guicheney, Pascale, Schwartz, Peter J, Horie, Minoru

“…Acquired long QT syndrome (aLQTS) exhibits QT prolongation and Torsades de Pointes ventricular tachycardia triggered by drugs, hypokalaemia, or bradycardia…”
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Differential Diagnosis Between Catecholaminergic Polymorphic Ventricular Tachycardia and Long QT Syndrome Type 1　― Modified Schwartz Score by Ozawa, Junichi, Ohno, Seiko, Fujii, Yusuke, Makiyama, Takeru, Suzuki, Hiroshi, Saitoh, Akihiko, Horie, Minoru

“…Background: Catecholaminergic polymorphic ventricular tachycardia (CPVT) has been often misdiagnosed as long QT syndrome (LQTS) type 1 (LQT1), which…”
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An NGS-based genotyping in LQTS; minor genes are no longer minor by Ohno, Seiko, Ozawa, Junichi, Fukuyama, Megumi, Makiyama, Takeru, Horie, Minoru

“…Mutations in KCNQ1, KCNH2, and SCN5A are the major cause of long QT syndrome (LQTS). More than 90% of the genotyped patients have been reported to carry…”
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Co-Phenotype of Left Ventricular Non-Compaction Cardiomyopathy and Atypical Catecholaminergic Polymorphic Ventricular Tachycardia in Association With R169Q, a Ryanodine Receptor Type 2 Missense Mutation by Nozaki, Yoshihiro, Kato, Yoshiaki, Uike, Kiyoshi, Yamamura, Kenichiro, Kikuchi, Masahiro, Yasuda, Maki, Ohno, Seiko, Horie, Minoru, Murayama, Takashi, Kurebayashi, Nagomi, Horigome, Hitoshi

“…Background:Left ventricular non-compaction (LVNC) is a cardiomyopathy characterized by prominent trabeculae and intertrabecular recesses. We present the cases…”
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Bradycardia Is a Specific Phenotype of Catecholaminergic Polymorphic Ventricular Tachycardia Induced by RYR2 Mutations by Miyata, Kazuaki, Ohno, Seiko, Itoh, Hideki, Horie, Minoru

“…Objective Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a lethal inherited disease characterized by ventricular arrhythmias induced by…”
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Ultrastructural Maturation of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes in a Long-Term Culture by Kamakura, Tsukasa, Makiyama, Takeru, Sasaki, Kenichi, Yoshida, Yoshinori, Wuriyanghai, Yimin, Chen, Jiarong, Hattori, Tetsuhisa, Ohno, Seiko, Kita, Toru, Horie, Minoru, Yamanaka, Shinya, Kimura, Takeshi

“…Background: In the short- to mid-term, cardiomyocytes generated from human-induced pluripotent stem cells (hiPSC-CMs) have been reported to be less mature than…”
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Functionally validated SCN5A variants allow interpretation of pathogenicity and prediction of lethal events in Brugada syndrome by Ishikawa, Taisuke, Kimoto, Hiroki, Mishima, Hiroyuki, Yamagata, Kenichiro, Ogata, Soshiro, Aizawa, Yoshiyasu, Hayashi, Kenshi, Morita, Hiroshi, Nakajima, Tadashi, Nakano, Yukiko, Nagase, Satoshi, Murakoshi, Nobuyuki, Kowase, Shinya, Ohkubo, Kimie, Aiba, Takeshi, Morimoto, Shimpei, Ohno, Seiko, Kamakura, Shiro, Nogami, Akihiko, Takagi, Masahiko, Karakachoff, Matilde, Dina, Christian, Schott, Jean-Jacques, Yoshiura, Koh-Ichiro, Horie, Minoru, Shimizu, Wataru, Nishimura, Kunihiro, Kusano, Kengo, Makita, Naomasa

“…Abstract Aims The prognostic value of genetic variants for predicting lethal arrhythmic events (LAEs) in Brugada syndrome (BrS) remains controversial. We…”
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Holter Electrocardiographic Approach to Predicting Outcomes of Pediatric Patients With Long QT Syndrome by Yoshinaga, Masao, Ninomiya, Yumiko, Tanaka, Yuji, Fukuyama, Megumi, Kato, Koichi, Ohno, Seiko, Horie, Minoru, Ogata, Hiromitsu

“…Background: This study was performed to clarify the clinical findings of pediatric patients diagnosed with long QT syndrome (LQTS) through electrocardiographic…”
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Cardiomyopathy with an LMNA Genetic Variant Affecting Three Consecutive Generations: A Case Series by Ogawa, Naoko, Kondo, Hidekazu, Ishii, Yumi, Mitarai, Kazuki, Akiyoshi, Kumiko, Niwa, Hiroko, Kato, Koichi, Horie, Minoru, Ohno, Seiko, Takahashi, Naohiko

“…We report the case of a family afflicted with cardiac laminopathy who showed atrial fibrillation (AF) and complete atrioventricular block across three…”
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Autonomic Function and QT Interval During Night-Time Sleep in Infant Long QT Syndrome by Yoshinaga, Masao, Kucho, Yu, Ushinohama, Hiroya, Ishikawa, Yuichi, Ohno, Seiko, Ogata, Hiromitsu

“…Background:Sudden infant death syndrome mainly occurs during night-time sleep. Approximately 10% of cases are thought to involve infants with long QT syndrome…”
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A de novo gain-of-function KCND3 mutation in early repolarization syndrome by Takayama, Koichiro, Ohno, Seiko, Ding, Wei-Guang, Ashihara, Takashi, Fukumoto, Daisuke, Wada, Yuko, Makiyama, Takeru, Kise, Hiroaki, Hoshiai, Minako, Matsuura, Hiroshi, Horie, Minoru

“…Early repolarization syndrome (ERS) is characterized by J-point elevation on electrocardiograms and ventricular fibrillation (VF). Early repolarization arises…”
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Cytosolic Ca2+-dependent Ca2+ release activity primarily determines the ER Ca2+ level in cells expressing the CPVT-linked mutant RYR2 by Kurebayashi, Nagomi, Murayama, Takashi, Ota, Ryosaku, Suzuki, Junji, Kanemaru, Kazunori, Kobayashi, Takuya, Ohno, Seiko, Horie, Minoru, Iino, Masamitsu, Yamashita, Fumiyoshi, Sakurai, Takashi

“…Type 2 ryanodine receptor (RYR2) is a cardiac Ca2+ release channel in the ER. Mutations in RYR2 are linked to catecholaminergic polymorphic ventricular…”
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