Search Results - "Ohnmacht, Galen A."

Gene-expression profiling of the response of peripheral blood mononuclear cells and melanoma metastases to systemic IL-2 administration by Panelli, Monica C, Wang, Ena, Phan, Giao, Puhlmann, Markus, Miller, Lance, Ohnmacht, Galen A, Klein, Harvey G, Marincola, Francesco M

“…Interleukin-2 (IL-2) has direct pluripotent effects on cells with immune and inflammatory function. Which of these effects has a critical role in mediating…”
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Kinetics of cytokine expression in melanoma metastases classifies immune responsiveness by Mocellin, Simone, Ohnmacht, Galen A., Wang, Ena, Marincola, Francesco M.

“…Production of cytokines (CKs) in the tumor micro‐environment may modulate tumor–host interactions. However, pre‐clinical models often provide conflicting data…”
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Unmasking cryptic epitopes after loss of immunodominant tumor antigen expression through epitope spreading by Lally, Kate M., Mocellin, Simone, Ohnmacht, Galen A., Nielsen, Mai‐Britt, Bettinotti, Maria, Panelli, Monica C., Monsurro, Vladia, Marincola, Francesco M.

“…The basis of intra‐tumoral and systemic T cell reactivity toward cancer remains unclear. In particular the role that peripheral stimuli, whether endogenous or…”
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High-fidelity mRNA amplification for gene profiling by Marincola, Francesco M, Wang, Ena, Miller, Lance D, Ohnmacht, Galen A, Liu, Edison T

“…The completion of the Human Genome Project has made possible the comprehensive analysis of gene expression, and cDNA microarrays are now being employed for…”
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Prospective molecular profiling of melanoma metastases suggests classifiers of immune responsiveness by ENA WANG, MILLER, Lance D, ALEXANDER, H. Richard, DURAY, Paul H, HERLYN, Meenhard, RESTIFO, Nicholas P, LIU, Edison T, ROSENBERG, Steven A, MARINCOLA, Francesco M, OHNMACHT, Galen A, MOCELLIN, Simone, PEREZ-DIEZ, Ainhoa, PETERSEN, David, YINGDONG ZHAO, SIMON, Richard, POWELL, John I, ASAKI, Esther

“…We amplified RNAs from 63 fine needle aspiration (FNA) samples from 37 s.c. melanoma metastases from 25 patients undergoing immunotherapy for hybridization to…”
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Failed Antireflux Surgery: Results After Reoperation by Ohnmacht, Galen A., Deschamps, Claude, Cassivi, Stephen D., Nichols, Francis C., Allen, Mark S., Schleck, Cathy D., Pairolero, Peter C.

“…Since laparoscopy has become a common surgical approach for antireflux surgery, little is known regarding reoperation for failed antireflux surgery. Records of…”
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Functional Analysis of Antigen-Specific T Lymphocytes by Serial Measurement of Gene Expression in Peripheral Blood Mononuclear Cells and Tumor Specimens by Kammula, Udai S, Lee, Kang-Hun, Riker, Adam I, Wang, Ena, Ohnmacht, Galen A, Rosenberg, Steven A, Marincola, Francesco M

“…The cloning of cancer Ags recognized by T cells has provided potentially new tools to enhance immunity against metastatic cancer. The biological monitoring of…”
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Short-Term Kinetics of Tumor Antigen Expression in Response to Vaccination by Ohnmacht, Galen A, Wang, Ena, Mocellin, Simone, Abati, Andrea, Filie, Armando, Fetsch, Patricia, Riker, Adam I, Kammula, Udai S, Rosenberg, Steven A, Marincola, Francesco M

“…The melanoma patient's immune response to tumor has been extensively studied. Yet, the frequently observed coexistence of tumor-associated Ag (TAA)-specific T…”
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Sequential 5-aza-2'-deoxycytidine-depsipeptide FR901228 treatment induces apoptosis preferentially in cancer cells and facilitates their recognition by cytolytic T lymphocytes specific for NY-ESO-1 by WEISER, Todd S, SHENG GUO, Z, STEWART, John H, NGUYEN, Dao M, ROSENBERG, Steven A, SCHRUMP, David S, OHNMACHT, Galen A, PARKHURST, Maria L, TONG-ON, Panida, MARINCOLA, Francesco M, FISCHETTE, Maria R, XIAODAN YU, CHEN, G. Aaron, HONG, Julie A

“…Global alterations in chromatin structure profoundly influence gene expression in thoracic neoplasms, silencing tumor suppressors while facilitating the…”
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Induction of MAGE-3 expression in lung and esophageal cancer cells by Weiser, Todd S, Ohnmacht, Galen A, Guo, Zong S, Fischette, Maria R, Chen, Gustavio A, Hong, Julie A, Nguyen, Dao M, Schrump, David S

“…Background. Although MAGE-3 has been detected in approximately 40% of lung and esophageal cancers, expression of this cancer testis antigen appears to be below…”
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A Tumor-Infiltrating Lymphocyte from a Melanoma Metastasis with Decreased Expression of Melanoma Differentiation Antigens Recognizes MAGE-12 by Panelli, Monica C, Bettinotti, Maria P, Lally, Kate, Ohnmacht, Galen A, Li, Yong, Robbins, Paul, Riker, Adam, Rosenberg, Steven A, Marincola, Francesco M

“…Twenty separate tumor infiltrating lymphocyte (TIL) bulk cultures and a tumor cell line were originated simultaneously from a fine needle aspiration biopsy of…”
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Melanoma-reactive CD8+ T cells recognize a novel tumor antigen expressed in a wide variety of tumor types by HARADA, Mamoru, LI, Yong F, EL-GAMIL, Mona, OHNMACHT, Galen A, ROSENBERG, Steven A, ROBBINS, Paul F

“…An autologous melanoma cell line selected for loss of expression of the immunodominant MART-1 and gp100 antigens was initially used to carry out a mixed…”
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A prospective, randomized, double-blind, placebo-controlled trial evaluating the effect of nystatin on the development of oral irritation in patients receiving high-dose intravenous Interleukin-2 by OHNMACHT, Galen A, PHAN, Giao Q, ROGERS-FREEZER, Linda J, SEIPP, Claudia A, ROSENBERG, Steven A, MARINCOLA, Francesco M, MAVROUKAKIS, Sharon A, STEINBERG, Seth M, SHEA, Yvonne R, WITEBSKY, Frank G, MCINTYRE, Lori S, GOODWIN, Rose S, MUEHLBAUER, Paula M, MORTON, Kathleen E

“…Interleukin-2 (IL-2) has been used to treat patients with metastatic melanoma and renal cell cancer for nearly two decades, and much progress has been made in…”
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Identification of fibroblast growth factor-5 as an overexpressed antigen in multiple human adenocarcinomas by HANADA, Ken-Ichi, PERRY-LALLEY, Donna M, OHNMACHT, Galen A, BETTINOTTI, Maria P, YANG, James C

“…Methodology for identifying tumor-associated antigens recognized by T cells has been successfully used to clone antigens from melanoma cells. Similar efforts…”
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Threshold levels of gene expression of the melanoma antigen gp100 correlate with tumor cell recognition by cytotoxic T lymphocytes by Riker, Adam I., Kammula, Udai S., Panelli, Monica C., Wang, Ena, Ohnmacht, Galen A., Steinberg, Seth M., Rosenberg, Steven A., Marincola, Francesco M.

“…The level of expression of melanoma antigens (MA) may modulate the host immunologic response. Thus, the accurate measurement of MA expression may allow proper…”
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Heterogeneity in expression of human leukocyte antigens and melanoma-associated antigens in advanced melanoma by Ohnmacht, Galen A., Marincola, Francesco M.

“…The study of tumor immunology has led to many innovative therapeutic strategies for the treatment of melanoma. The strategies are primarily dependent on…”
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Failed antireflux surgery : Results after reoperation. Discussion by OHNMACHT, Galen A, DESCHAMPS, Claude, CASSIVI, Stephen D, NICHOLS, Francis C, ALLEN, Mark S, SCHLECK, Cathy D, PAIROLERO, Peter C, LUKETICH, James, MILLER, Daniel L

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Induction of MAGE-3 expression in lung and esophageal cancer cells. Discussion by WEISER, Todd S, OHNMACHT, Galen A, GUO, Zong S, FISCHETTE, Maria R, CHEN, Gustavio A, HONG, Julie A, NGUYEN, Dao M, SCHRUMP, David S, BLOCK, Mark I, DECAMP, Malcolm M

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