Search Results - "Ohmen, Jeffrey D."

Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits by Ghazalpour, Anatole, Rau, Christoph D, Farber, Charles R, Bennett, Brian J, Orozco, Luz D, van Nas, Atila, Pan, Calvin, Allayee, Hooman, Beaven, Simon W, Civelek, Mete, Davis, Richard C, Drake, Thomas A, Friedman, Rick A, Furlotte, Nick, Hui, Simon T, Jentsch, J. David, Kostem, Emrah, Kang, Hyun Min, Kang, Eun Yong, Joo, Jong Wha, Korshunov, Vyacheslav A, Laughlin, Rick E, Martin, Lisa J, Ohmen, Jeffrey D, Parks, Brian W, Pellegrini, Matteo, Reue, Karen, Smith, Desmond J, Tetradis, Sotirios, Wang, Jessica, Wang, Yibin, Weiss, James N, Kirchgessner, Todd, Gargalovic, Peter S, Eskin, Eleazar, Lusis, Aldons J, LeBoeuf, Renée C

“…We have developed an association-based approach using classical inbred strains of mice in which we correct for population structure, which is very extensive in…”
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Genome-wide association analysis demonstrates the highly polygenic character of age-related hearing impairment by Fransen, Erik, Bonneux, Sarah, Corneveaux, Jason J, Schrauwen, Isabelle, Di Berardino, Federica, White, Cory H, Ohmen, Jeffrey D, Van de Heyning, Paul, Ambrosetti, Umberto, Huentelman, Matthew J, Van Camp, Guy, Friedman, Rick A

“…We performed a genome-wide association study (GWAS) to identify the genes responsible for age-related hearing impairment (ARHI), the most common form of…”
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GRM7 variants confer susceptibility to age-related hearing impairment by Friedman, Rick A., Van Laer, Lut, Huentelman, Matthew J., Sheth, Sonal S., Van Eyken, Els, Corneveaux, Jason J., Tembe, Waibhav D., Halperin, Rebecca F., Thorburn, Ashley Q., Thys, Sofie, Bonneux, Sarah, Fransen, Erik, Huyghe, Jeroen, Pyykkö, Ilmari, Cremers, Cor W.R.J., Kremer, Hannie, Dhooge, Ingeborg, Stephens, Dafydd, Orzan, Eva, Pfister, Markus, Bille, Michael, Parving, Agnete, Sorri, Martti, Van de Heyning, Paul H., Makmura, Linna, Ohmen, Jeffrey D., Linthicum, Frederick H., Fayad, Jose N., Pearson, John V., Craig, David W., Stephan, Dietrich A., Van Camp, Guy

“…Age-related hearing impairment (ARHI), or presbycusis, is the most prevalent sensory impairment in the elderly. ARHI is a complex disease caused by an…”
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Large-scale phenotyping of noise-induced hearing loss in 100 strains of mice by Myint, Anthony, White, Cory H., Ohmen, Jeffrey D., Li, Xin, Wang, Juemei, Lavinsky, Joel, Salehi, Pezhman, Crow, Amanda L., Ohyama, Takahiro, Friedman, Rick A.

“…A cornerstone technique in the study of hearing is the Auditory Brainstem Response (ABR), an electrophysiologic technique that can be used as a quantitative…”
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A genome‐wide search identifies potential new susceptibility loci for Crohn's disease by Ma, Yuanhong, Ohmen, Jeffrey D., Li, Zhiming, Bentley, L. Gordon, McElree, Colleen, Pressman, Sheila, Targan, Stephan R., Fischel‐Ghodsian, Nathan, Rotter, Jerome I., Yang, Huiying

“…Chronic inflammatory bowel disease (IBD) presents as two major clinical forms, Crohn's disease (CD) and ulcerative colitis (UC). Genetic epidemiological…”
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Genome-wide screening for genetic loci associated with noise-induced hearing loss by White, Cory H, Ohmen, Jeffrey D, Sheth, Sonal, Zebboudj, Amina F, McHugh, Richard K, Hoffman, Larry F, Lusis, Aldons J, Davis, Richard C, Friedman, Rick A

“…Noise-induced hearing loss (NIHL) is one of the more common sources of environmentally induced hearing loss in adults. In a mouse model, Castaneous (CAST/Ei)…”
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FVB/NJ Mice Demonstrate a Youthful Sensitivity to Noise-Induced Hearing Loss and Provide a Useful Genetic Model for the Study of Neural Hearing Loss by Ho, Maria K., Li, Xin, Wang, Juemei, Ohmen, Jeffrey D., Friedman, Rick A.

“…The hybrid mouse diversity panel (HMDP), a panel of 100 strains, has been employed in genome wide association studies (GWAS) to study complex traits in mice…”
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Selective Accumulation of T Cells According to T-Cell Receptor Vβ Gene Usage in Skin Cancer by Ohmen, Jeffrey D, Moy, Ronald L, Zovich, Daniel, Lieberman, Amara, Wyzykowski, Richard J, Sullivan, Laura, Modlin, Robert L, Uyemura, Koichi

“…To investigate whether specific T-cell populations are overrepresented in tumor-infiltrating lymphocytes (TIL) in skin cancer, we determined the T-cell…”
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Selective Expansion of Vδ1 + T Cells from Leprosy Skin Lesions by Uyemura, Koichi, Ho, Christopher T, Ohmen, Jeffrey D, Rea, Thomas H, Modlin, Robert L

“…T cells bearing γδ T-cell receptors (TCRs) are prominent residents of murine epidermis and appear to be important participants in the immune response to…”
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A genome-wide search identifies potential new susceptibility loci for Crohn's disease by Ma, Y, Ohmen, J D, Li, Z, Bentley, L G, McElree, C, Pressman, S, Targan, S R, Fischel-Ghodsian, N, Rotter, J I, Yang, H

“…Chronic inflammatory bowel disease (IBD) presents as two major clinical forms, Crohn's disease (CD) and ulcerative colitis (UC). Genetic epidemiological…”
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Overexpression of IL-10 in atopic dermatitis. Contrasting cytokine patterns with delayed-type hypersensitivity reactions by Ohmen, JD, Hanifin, JM, Nickoloff, BJ, Rea, TH, Wyzykowski, R, Kim, J, Jullien, D, McHugh, T, Nassif, AS, Chan, SC

“…The skin lesions of patients with atopic dermatitis provide a model to study immunoregulation in human allergy. To determine the local cytokine pattern of…”
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Susceptibility Locus for Inflammatory Bowel Disease on Chromosome 16 has a Role in Crohn's disease, but Not in Ulcerative Colitis by Ohmen, Jeffrey D., Yang, Hui-Ying, Yamamoto, Karen K., Zhao, Hong-Yu, Ma, Yuanhong, Bentley, L. Gordon, Huang, Zhihan, Gerwehr, Scott, Pressman, Sheila, McElree, Colleen, Targan, Stephan, Rotter, Jerome I., Fischel-Ghodsian, Nathan

“…In the Western world, chronic inflammatory bowel disease (IBD) presents as two major clinical forms, Crohn's disease (CD) and ulcerative colitis (UC)…”
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Cytokine patterns of immunologically mediated tissue damage by Yamamura, M, Wang, XH, Ohmen, JD, Uyemura, K, Rea, TH, Bloom, BR, Modlin, RL

“…Reactional states in leprosy are produced by different immunologic mechanisms and are responsible for a major component of tissue damage of the disease…”
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Local expression of antiinflammatory cytokines in cancer by YAMAMURA, M, MODLIN, R. L, OHMEN, J. D, MOY, R. L

“…To characterize the nature of the local cytokine response to cancer, we chose to investigate cytokine patterns in biopsy specimens of basal cell carcinoma…”
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Evidence for a superantigen in human tuberculosis by Ohmen, J D, Barnes, P F, Grisso, C L, Bloom, B R, Modlin, R L

“…T cells are not only required for resistance to tuberculosis, but they likely contribute to the tissue damage characteristic of the disease. To define better…”
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The T cell receptors of human γδ T cells reactive to Mycobacterium tuberculosis are encoded by specific V genes but diverse V-J junctions by OHMEN, J. D, BARNES, P. F, UYEMURA, K, SHUZHUANG LU, GRISSO, C. L, MODLIN, R. L

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Selection of T Lymphocytes Bearing Limited T-Cell Receptor β Chains in the Response to a Human Pathogen by Wang, Xiao-Hong, Ohmen, Jeffrey D., Uyemura, Koichi, Rea, Thomas H., Kronenberg, Mitchell, Modlin, Robert L.

“…Delayed-type hypersensitivity (DTH) is a classic measure of T-cell responsiveness to foreign antigen. To estimate the extent of the T-cell repertoire in the…”
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T cells bearing Vβ6 T cell receptors in the cell-mediated immune response to Mycobacterium leprae by XIAOHONG WANG, GOLKAR, L, UYEMURA, K, OHMEN, J. D, VILLAHERMOSA, L. G, FAJARDO, T. T, CELLONA, R. V, WALSH, G. P, MODLIN, R. L

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Selection of T lymphocytes bearing limited T-cell receptor (Beta) chains in the response to a human pathogen by Xiao-Hong, Wang, Ohmen, Jeffrey D, Uyemura, Koichi, Rea, Thomas H

“…It is suggested that the mechanism by which major histocompatibility complex haplotype influences delayed-type hypersensitivity in this disease involves the…”
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Molecular cloning and nucleotide sequence of the nuclear PET122 gene required for expression of the mitochondrial COX3 gene in S.cerevisiae by Ohmen, J. D., Kloeckener-Gruissem, B., McEwen, J. E.

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