Search Results - "Ohishi, Minako"

Supermolecular Structure of the Enteropathogenic Escherichia coli Type III Secretion System and Its Direct Interaction with the EspA-Sheath-like Structure by Sekiya, Kachiko, Ohishi, Minako, Ogino, Tomoaki, Tamano, Koichi, Sasakawa, Chihiro, Abe, Akio

“…Enteropathogenic Escherichia coli (EPEC) secretes several Esp proteins via the type III secretion system (secreton). EspA, EspB, and EspD are required for…”
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Critical roles of Pten in B cell homeostasis and immunoglobulin class switch recombination by Suzuki, Akira, Kaisho, Tsuneyasu, Ohishi, Minako, Tsukio-Yamaguchi, Manae, Tsubata, Takeshi, Koni, Pandelakis A, Sasaki, Takehiko, Mak, Tak Wah, Nakano, Toru

“…Pten is a tumor suppressor gene mutated in human cancers. We used the Cre-loxP system to generate a B cell-specific mutation of Pten in mice…”
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Diphtheria Toxin Mutant CRM197 Possesses Weak EF2-ADP-ribosyl Activity that Potentiates its Anti-tumorigenic Activity by Kageyama, Takuya, Ohishi, Minako, Miyamoto, Shingo, Mizushima, Hiroto, Iwamoto, Ryo, Mekada, Eisuke

“…CRM197, a mutated diphtheria toxin (DT), has long been recognized to be a non-toxic protein. Based on its non-toxic feature, this protein has been utilized for…”
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Humanized Gene Replacement in Mice Reveals the Contribution of Cancer Stroma-Derived HB-EGF to Tumor Growth by Ichise, Tomoko, Adachi, Satoshi, Ohishi, Minako, Ikawa, Masahito, Okabe, Masaru, Iwamoto, Ryo, Mekada, Eisuke

“…Tumor progression is a complex process that involves the interaction of cancer cells with the cancer-surrounding stromal cells. The cancer stroma influences…”
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Cytoplasmic Domain Phosphorylation of Heparin-Binding EGF-like Growth Factor by Wang, Xiaobiao, Mizushima, Hiroto, Adachi, Satoshi, Ohishi, Minako, Iwamoto, Ryo, Mekada, Eisuke

“…Heparin-binding EGF-like growth factor (HB-EGF) is synthesized as a transmembrane precursor protein that is anchored to the plasma membrane. The extracellular…”
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BopB is a type III secreted protein in Bordetella bronchiseptica and is required for cytotoxicity against cultured mammalian cells by Kuwae, Asaomi, Ohishi, Minako, Watanabe, Mineo, Nagai, Masaaki, Abe, Akio

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BK-UM in patients with recurrent ovarian cancer or peritoneal cancer: a first-in-human phase-I study by Miyamoto, Shingo, Yotsumoto, Fusanori, Ueda, Taeko, Fukami, Tatsuya, Sanui, Ayako, Miyata, Kohei, Nam, Sung Ouk, Fukagawa, Satoshi, Katsuta, Takahiro, Maehara, Miyako, Kondo, Haruhiko, Miyahara, Daisuke, Shirota, Kyoko, Yoshizato, Toshiyuki, Kuroki, Masahide, Nishikawa, Hiroaki, Saku, Keijiro, Tsuboi, Yoshio, Ishitsuka, Kenji, Takamatsu, Yasushi, Tamura, Kazuo, Matsunaga, Akira, Hachisuga, Toru, Nishino, Shinsuke, Odawara, Takashi, Maeda, Kazuhiro, Manabe, Sadao, Ishikawa, Toyokazu, Okuno, Yoshinobu, Ohishi, Minako, Hikita, Tomoya, Mizushima, Hiroto, Iwamoto, Ryo, Mekada, Eisuke

“…BK-UM (CRM197) is a mutant form of diphtheria toxin and a specific inhibitor of heparin-binding epidermal growth factor-like growth factor (HB-EGF). We…”
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Prediction and Testing of Novel Transcriptional Networks Regulating Embryonic Stem Cell Self-Renewal and Commitment by Walker, Emily, Ohishi, Minako, Davey, Ryan E., Zhang, Wen, Cassar, Paul A., Tanaka, Tetsuya S., Der, Sandy D., Morris, Quaid, Hughes, Timothy R., Zandstra, Peter W., Stanford, William L.

“…Stem cell fate is governed by the integration of intrinsic and extrinsic positive and negative signals upon inherent transcriptional networks. To identify…”
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Keratinocyte-specific Pten deficiency results in epidermal hyperplasia, accelerated hair follicle morphogenesis and tumor formation by SUZUKI, Akira, ITAMI, Satoshi, TAK WAH MAK, NAKANO, Toru, OHISHI, Minako, HAMADA, Koichi, INOUE, Tae, KOMAZAWA, Nobuyasu, SENOO, Haruki, SASAKI, Takehiko, TAKEDA, Junji, MANABE, Motomu

“…PTEN is a tumor suppressor gene mutated in many human cancers. We used the Cre-loxP system to generate a keratinocyte-specific null mutation of Pten in mice…”
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BopB is a type III secreted protein in Bordetella bronchiseptica and is required for cytotoxicity against cultured mammalian cells by Kuwae, Asaomi, Ohishi, Minako, Watanabe, Mineo, Nagai, Masaaki, Abe, Akio

“…Summary The cytotoxicity of Bordetella bronchiseptica to infected cells is known to be dependent on a B. bronchiseptica type III secretion system. Although the…”
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The Centre for Modeling Human Disease Gene Trap resource by To, Christine, Epp, Trevor, Reid, Tammy, Lan, Qing, Yu, Mei, Li, Carol Y. J., Ohishi, Minako, Hant, Paula, Tsao, Nora, Casallo, Guillermo, Rossant, Janet, Osborne, Lucy R., Stanford, William L.

“…Gene trap mutagenesis of mouse embryonic stem cells generates random loss‐of‐function mutations, which can be identified by a sequence tag and can often report…”
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