Search Results - "Ohguchi, H."

KDM6B modulates MAPK pathway mediating multiple myeloma cell growth and survival by Ohguchi, H, Harada, T, Sagawa, M, Kikuchi, S, Tai, Y-T, Richardson, P G, Hideshima, T, Anderson, K C

“…Recent studies have delineated cancer-type-specific roles of histone 3 lysine 27 (H3K27) demethylase KDM6B/JMJD3 depending on its H3K27 demethylase activity…”
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Magnetic Property Investigation of High-Strength Electrical Steel Sheet Applied to Interior Permanent Magnet Synchronous Motors Considering Multiaxial Stress Caused by Centrifugal Force by Yamazaki, K., Ishikawa, K., Ohguchi, H., Imamori, S., Shuto, M.

“…The magnetic properties of high-strength electrical steel sheet applied to interior permanent magnet motors are investigated from both results of material…”
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Histone deacetylase 3 as a novel therapeutic target in multiple myeloma by Minami, J, Suzuki, R, Mazitschek, R, Gorgun, G, Ghosh, B, Cirstea, D, Hu, Y, Mimura, N, Ohguchi, H, Cottini, F, Jakubikova, J, Munshi, N C, Haggarty, S J, Richardson, P G, Hideshima, T, Anderson, K C

“…Histone deacetylases (HDACs) represent novel molecular targets for the treatment of various types of cancers, including multiple myeloma (MM). Many HDAC…”
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HDAC3 regulates DNMT1 expression in multiple myeloma: therapeutic implications by Harada, T, Ohguchi, H, Grondin, Y, Kikuchi, S, Sagawa, M, Tai, Y-T, Mazitschek, R, Hideshima, T, Anderson, K C

“…Epigenetic signaling pathways are implicated in tumorigenesis and therefore histone deacetylases (HDACs) represent novel therapeutic targets for cancers,…”
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Class IIa HDAC inhibition enhances ER stress-mediated cell death in multiple myeloma by Kikuchi, S, Suzuki, R, Ohguchi, H, Yoshida, Y, Lu, D, Cottini, F, Jakubikova, J, Bianchi, G, Harada, T, Gorgun, G, Tai, Y-T, Richardson, P G, Hideshima, T, Anderson, K C

“…Histone deacetylase (HDAC) inhibitors have been extensively investigated as therapeutic agents in cancer. However, the biological role of class IIa HDACs…”
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Mechanisms of PTHrP‐induced inhibition of smooth muscle contractility in the guinea pig gastric antrum by Ohguchi, H., Mitsui, R., Imaeda, K., Joh, T., Hashitani, H.

“…Background Parathyroid hormone‐related protein (PTHrP) that causes hypercalcemia of malignancy appears to function as an endogenous smooth muscle relaxant. For…”
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Small-molecule multi-targeted kinase inhibitor RGB-286638 triggers P53-dependent and -independent anti-multiple myeloma activity through inhibition of transcriptional CDKs by Cirstea, D, Hideshima, T, Santo, L, Eda, H, Mishima, Y, Nemani, N, Hu, Y, Mimura, N, Cottini, F, Gorgun, G, Ohguchi, H, Suzuki, R, Loferer, H, Munshi, N C, Anderson, K C, Raje, N

“…Small-molecule multi-targeted cyclin-dependent kinase (CDK) inhibitors (CDKIs) are of particular interest due to their potent antitumor activity independent of…”
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Rational combination treatment with histone deacetylase inhibitors and immunomodulatory drugs in multiple myeloma by Hideshima, T, Cottini, F, Ohguchi, H, Jakubikova, J, Gorgun, G, Mimura, N, Tai, Y-T, Munshi, N C, Richardson, P G, Anderson, K C

“…Immunomodulatory drugs (IMiDs) thalidomide, lenalidomide (Len) and pomalidomide trigger anti-tumor activities in multiple myeloma (MM) by targetting cereblon…”
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Anti-tumor activities of selective HSP90α/β inhibitor, TAS-116, in combination with bortezomib in multiple myeloma by Suzuki, R, Hideshima, T, Mimura, N, Minami, J, Ohguchi, H, Kikuchi, S, Yoshida, Y, Gorgun, G, Cirstea, D, Cottini, F, Jakubikova, J, Tai, Y-T, Chauhan, D, Richardson, P G, Munshi, N C, Utsugi, T, Anderson, K C

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A novel approach to practical matrix converter motor drive system with reverse blocking IGBT by Jun-ichi Itoh, Sato, I., Odaka, A., Ohguchi, H., Kodachi, H., Eguchi, N.

“…This paper proposes a novel control strategy and a protection circuit and shows the advantage of utilizing a newly developed reverse blocking insulated gate…”
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An Improvement Method of Matrix Converter Drives Under Input Voltage Disturbances by Sato, I., Itoh, J., Ohguchi, H., Odaka, A., Mine, H.

“…While the matrix converter has many advantages that include bidirectional power flow, a size reduction, a long lifetime, and sinusoidal input currents, it is…”
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Orientation and magnetic properties of FePt and CoPt films grown on MgO(1 1 0) single-crystal substrate by electron-beam coevaporation by Yu, Minghui, Ohguchi, H., Zambano, A., Takeuchi, I., Liu, J.P., Josell, D., Bendersky, L.A.

“…We have studied the orientation and magnetic properties of FePt and CoPt films deposited by electron-beam co-evaporation on MgO(1 1 0) single-crystal…”
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In situ photoemission characterization of terminating-layer-controlled La0.6Sr0.4MnO3 thin films by Kumigashira, H., Horiba, K., Ohguchi, H., Ono, K., Oshima, M., Nakagawa, N., Lippmaa, M., Kawasaki, M., Koinuma, H.

“…We report on the fabrication of terminating-layer-controlled La0.6Sr0.4MnO3 (LSMO) thin films and in situ characterization of the films using photoemission…”
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New pre-soaking technique for PADC and application to wide-range personal neutron dosimeter by Ohguchi, H., Oda, K., Yamauchi, T., Nakamura, T., Maki, D.

“…Poly allyl diglycol carbonate (PADC) plastic has been widely used as one of most sensitive detectors for personal neutron dosimeter. However, a considerably…”
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Variation of absorbed doses onboard of ISS Russian Service Module as measured with passive detectors by Jadrníčková, I., Tateyama, R., Yasuda, N., Kawashima, H., Kurano, M., Uchihori, Y., Kitamura, H., Akatov, Yu, Shurshakov, V., Kobayashi, I., Ohguchi, H., Koguchi, Y., Spurný, F.

“…Cosmic radiation represents possible risk for the astronauts. For estimation of the radiation onboard the spacecraft in space flights, it is necessary to…”
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Myeloablative Cord Blood Transplantation for Adults With Hematological Malignancies Using Tacrolimus and Short-Term Methotrexate for Graft-Versus-Host Disease Prophylaxis: Single-Institution Analysis by Yamada, M.F, Miyamura, K, Fujiwara, T, Kohata, K, Okitsu, Y, Ohguchi, H, Yamamoto, J, Yokoyama, H, Tomiya, Y, Ishizawa, K, Kameoka, J, Harigae, H

“…Abstract We studied clinical outcomes of 25 adult patients with hematological malignancies who underwent cord blood transplantation (CBT) after a myeloablative…”
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Development of monoenergetic neutron calibration fields between 8 keV and 15 MeV by Baba, M., Takada, M., Iwasaki, T., Matsuyama, S., Nakamura, T., Ohguchi, H., Nakao, T., Sanami, T., Hirakawa, N.

“…For characterization and calibration of neutron dosimeters and spectrometers, monoenergetic neutron calibration fields have been developed at eight energy…”
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Fabrication of spin-frustrated Sm2Mo2O7 epitaxial films: High throughput optimization using a temperature gradient method by Nishimura, J., Fukumura, T., Ohtani, M., Taguchi, Y., Kawasaki, M., Ohkubo, I., Koinuma, H., Ohguchi, H., Ono, K., Oshima, M., Tokura, Y.

“…Epitaxial thin films of pyrochlore-type ferromagnetic molybdates Sm2Mo2O7, as a geometrically spin-frustrated system, were fabricated by a pulsed-laser…”
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Study of an improved Allyl Di-Glycol carbonate sheet for high energy proton detection by Ohguchi, H., Juto, N., Fujisaki, S., Migita, S., Koguchi, Y., Takada, M.

“…An allyl di-glycol carbonate (ADC) sheet which has been utilised as a neutron detector for personal dosimetry has recently been studied for its application as…”
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Megahertz operation of voltage-fed inverter for HID lamps using distributed constant line by Ohsato, M.H., Mao, Q., Ohguchi, H., Shimizu, T., Kimura, G., Takagi, H.

“…A novel type of solid-state ballast, which operates in the megahertz-range frequency, is presented in this paper. A circuit composed of a voltage-fed…”
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