Search Results - "Ohashi, Moe"

Exploring Receptor Binding Affinities and Hepatic Cell Association of N‑Acetyl‑d‑Galactosamine-Modified β‑Cyclodextrin-Based Polyrotaxanes for Liver-Targeted Therapies by Ohashi, Moe, Tamura, Atsushi, Yui, Nobuhiko

“…Acid-degradable polyrotaxanes (PRXs) containing threading β-cyclodextrins (β-CDs) are promising candidates for therapeutic applications of β-CDs in metabolic…”
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Terminal Structure of Triethylene Glycol-Tethered Chains on β‑Cyclodextrin-Threaded Polyrotaxanes Dominates Temperature Responsivity and Biointeractions by Ohashi, Moe, Tamura, Atsushi, Yui, Nobuhiko

“…Pharmacological and biomedical applications of cyclodextrin (CD)-threaded polyrotaxanes (PRXs) have gained increasing attention. We had previously investigated…”
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Oligo(ethylene glycol)-modified β-cyclodextrin-based polyrotaxanes for simultaneously modulating solubility and cellular internalization efficiency by Tamura, Atsushi, Ohashi, Moe, Yui, Nobuhiko

“…We developed stimuli-labile polyrotaxanes (PRXs) composed of β-cyclodextrin (β-CD), Pluronic as an axle polymer, and acid-cleavable N-triphenylmethyl groups as…”
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Acid-Induced Intracellular Dissociation of β‑Cyclodextrin-Threaded Polyrotaxanes Directed toward Attenuating Phototoxicity of Bisretinoids through Promoting Excretion by Tamura, Atsushi, Ohashi, Moe, Nishida, Kei, Yui, Nobuhiko

“…In the retinal pigment epithelium of patients with age-related macular degeneration (AMD), excess N-retinylidene-N-retinylethanolamine (A2E), a dimer of…”
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Effect of Alkyl Chain Length of Acylated α‐Cyclodextrin‐Threaded Polyrotaxanes on Thermoresponsive Phase Transition Behavior by Tamura, Atsushi, Ohashi, Moe, Tonegawa, Asato, Kang, Tae Woong, Zhang, Shunyao, Yui, Nobuhiko

“…The temperature‐dependent phase transition behavior of acetylated polyrotaxanes (PRXs) consisting of acylated α‐cyclodextrins threaded onto a poly(ethylene…”
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Japan-USA Orbital Atherectomy for Calcific Coronary Lesions: COAST Study, a Harmonization by Doing Proof-of-Concept: The Japanese and US Regulatory Perspective by Iwamoto, Shin, Ohashi, Moe, Shirato, Haruki, Ho, Mami, Malone, Misti, Cavanaugh, Kenneth

“…Regulatory approval processes for medical devices in Japan and the United States of America (US) often require similar clinical trials to establish safety and…”
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Global Medical Device Clinical Trials Involving Both the United States and Japan: Key Considerations for Development, Regulatory Approval, and Conduct by Iwamoto, Shin, Cavanaugh, Kenneth, Malone, Misti, Lottes, Aaron, Thatcher, Robert, Kumar, Katherine, Rowland, Steve, Fearnot, Neal, Uchida, Takahiro, Iwaishi, Chie, Senshu, Kazuhisa, Konishi, Ryo, Ikeda, Koji, Suzuki, Yuka, Ikeno, Fumiaki, Tamura, Atsushi, Ho, Mami, Ohashi, Moe, Katayama, Hiroshi, Krucoff, Mitchell W.

“…As medical device development becomes increasingly global, the opportunities and potential advantages offered by international clinical trial and regulatory…”
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