Search Results - "Oh, Yeounsun"

Recent advances in genome engineering by CRISPR technology by Lee, Youngsik, Oh, Yeounsun, Lee, Seung Hwan

“…Due to the development of CRISPR technology, the era of effective editing of target genes has arrived. However, the off-target problem that occurs when…”
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Prediction-based highly sensitive CRISPR off-target validation using target-specific DNA enrichment by Kang, Seung-Hun, Lee, Wi-jae, An, Ju-Hyun, Lee, Jong-Hee, Kim, Young-Hyun, Kim, Hanseop, Oh, Yeounsun, Park, Young-Ho, Jin, Yeung Bae, Jun, Bong-Hyun, Hur, Junho K., Kim, Sun-Uk, Lee, Seung Hwan

“…CRISPR effectors, which comprise a CRISPR-Cas protein and a guide (g)RNA derived from the bacterial immune system, are widely used for target-specific genome…”
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Author Correction: Prediction-based highly sensitive CRISPR off-target validation using target-specific DNA enrichment by Kang, Seung-Hun, Lee, Wi-jae, An, Ju-Hyun, Lee, Jong-Hee, Kim, Young-Hyun, Kim, Hanseop, Oh, Yeounsun, Park, Young-Ho, Jin, Yeung Bae, Jun, Bong-Hyun, Hur, Junho K., Kim, Sun-Uk, Lee, Seung Hwan

“…A Correction to this paper has been published: https://doi.org/10.1038/s41467-020-20559-5…”
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Expansion of the prime editing modality with Cas9 from Francisella novicida by Oh, Yeounsun, Lee, Wi-Jae, Hur, Junho K, Song, Woo Jeung, Lee, Youngjeon, Kim, Hanseop, Gwon, Lee Wha, Kim, Young-Hyun, Park, Young-Ho, Kim, Chan Hyoung, Lim, Kyung-Seob, Song, Bong-Seok, Huh, Jae-Won, Kim, Sun-Uk, Jun, Bong-Hyun, Jung, Cheulhee, Lee, Seung Hwan

“…Prime editing can induce a desired base substitution, insertion, or deletion in a target gene using reverse transcriptase after nick formation by CRISPR…”
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Development of CRISPR technology for precise single-base genome editing: a brief review by Lee, Hyomin K., Oh, Yeounsun, Hong, Juyoung, Lee, Seung Hwan, Hur, Junho K.

“…The clustered regularly interspaced short palindromic repeats (CRISPR) system is a family of DNA sequences originally discovered as a type of acquired immunity…”
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Utilization of nicking properties of CRISPR-Cas12a effector for genome editing by Kim, Chan Hyoung, Lee, Wi-jae, Oh, Yeounsun, Lee, Youngjeon, Lee, Hyomin K., Seong, Jung Bae, Lim, Kyung-Seob, Park, Sang Je, Huh, Jae-Won, Kim, Young-Hyun, Kim, Kyoung Mi, Hur, Junho K., Lee, Seung Hwan

“…The CRISPR-Cas nickase system for genome editing has attracted considerable attention owing to its safety, efficiency, and versatility. Although alternative…”
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Highly specific chimeric DNA-RNA-guided genome editing with enhanced CRISPR-Cas12a system by Kim, Hanseop, Lee, Wi-jae, Kim, Chan Hyoung, Oh, Yeounsun, Gwon, Lee Wha, Lee, Hyomin, Song, Woojeung, Hur, Junho K., Lim, Kyung-Seob, Jeong, Kang Jin, Nam, Ki-Hoan, Won, Young-Suk, Lee, Kyeong-Ryoon, Lee, Youngjeon, Kim, Young-Hyun, Huh, Jae-Won, Jun, Bong-Hyun, Lee, Dong-Seok, Lee, Seung Hwan

“…The clustered regularly interspaced short palindromic repeats (CRISPR)-Cas12a system is composed of a Cas12a effector that acts as a DNA-cleaving endonuclease…”
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Development of CRISPR technology for precise single-base genome editing: a brief review by Lee, Hyomin K, Oh, Yeounsun, Hong, Juyoung, Lee, Seung Hwan, Hur, Junho K

“…The clustered regularly interspaced short palindromic repeats (CRISPR) system is a family of DNA sequences originally discovered as a type of acquired immunity…”
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Recent application of CRISPR-Cas12 and OMEGA system for genome editing by Badon, Isabel Wen, Oh, Yeounsun, Kim, Ho-Joong, Lee, Seung Hwan

“…In 2012, it was discovered that precise gene editing could be induced in target DNA using the reprogrammable characteristics of the CRISPR system. Since then,…”
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Highly efficient and specific regulation of gene expression using enhanced CRISPR-Cas12f system by Oh, Yeounsun, Gwon, Lee Wha, Lee, Hyomin K., Hur, Junho K., Park, Kwang-Hyun, Kim, Kee-Pyo, Lee, Seung Hwan

“…The recently developed CRISPR activator (CRISPRa) system uses a CRISPR-Cas effector-based transcriptional activator to effectively control the expression of…”
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Enhancement of target specificity of CRISPR–Cas12a by using a chimeric DNA–RNA guide by Kim, Hanseop, Lee, Wi-jae, Oh, Yeounsun, Kang, Seung-Hun, Hur, Junho K, Lee, Hyomin, Song, WooJeung, Lim, Kyung-Seob, Park, Young-Ho, Song, Bong-Seok, Jin, Yeung Bae, Jun, Bong-Hyun, Jung, Cheulhee, Lee, Dong-Seok, Kim, Sun-Uk, Lee, Seung Hwan

“…Abstract The CRISPR–Cas9 system is widely used for target-specific genome engineering. CRISPR–Cas12a (Cpf1) is one of the CRISPR effectors that controls target…”
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