Search Results - "Oh, Seon‐Hee"

Polyubiquitination of p62/SQSTM1 is a prerequisite for Fas/CD95 aggregation to promote caspase-dependent apoptosis in cadmium-exposed mouse monocyte RAW264.7 cells by Jung, Ki-Tae, Oh, Seon-Hee

“…Cadmium(Cd) induces cytotoxicity via autophagy-induced apoptosis in non-activated mouse monocytes; however, the molecular mechanism remains unclear. Here, we…”
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Cytoplasmic sirtuin 6 translocation mediated by p62 polyubiquitination plays a critical role in cadmium-induced kidney toxicity by So, Keum-Young, Park, Byung-Hyun, Oh, Seon-Hee

“…Sirtuin 6 (Sirt6) is important for maintaining kidney homeostasis and function. Cd exposure increases the risk of developing kidney diseases. However, the role…”
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The role of autophagy in cadmium-induced acute toxicity in glomerular mesangial cells and tracking polyubiquitination of cytoplasmic p53 as a biomarker by Jung, Ki-Tae, Oh, Seon-Hee

“…Cadmium (Cd) is a highly toxic environmental pollutant that can severely damage the kidneys. Here, we show that Cd-induced apoptosis is promoted by the…”
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Autophagy induction by capsaicin in malignant human breast cells is modulated by p38 and extracellular signal-regulated mitogen-activated protein kinases and retards cell death by suppressing endoplasmic reticulum stress-mediated apoptosis by Choi, Cheol-Hee, Jung, Yong-Keun, Oh, Seon-Hee

“…In our previous study, we showed that capsaicin induces autophagy in several cell lines. Here, we investigated the molecular mechanisms of capsaicin-induced…”
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Endoplasmic reticulum stress-mediated autophagy/apoptosis induced by capsaicin (8-methyl-N-vanillyl-6-nonenamide) and dihydrocapsaicin is regulated by the extent of c-Jun NH2-terminal kinase/extracellular signal-regulated kinase activation in WI38 lung epithelial fibroblast cells by Oh, Seon-Hee, Lim, Sung-Chul

“…Endoplasmic reticulum (ER) stress causes cell survival or death, which is dependent on the type of cell and stimulus. Capsaicin…”
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Sirtuin 2 aggravates postischemic liver injury by deacetylating mitogen‐activated protein kinase phosphatase‐1 by Wang, Jie, Koh, Hyoung‐Won, Zhou, Lu, Bae, Ui‐Jin, Lee, Hwa‐Suk, Bang, In Hyuk, Ka, Sun‐O, Oh, Seon‐Hee, Bae, Eun Ju, Park, Byung‐Hyun

“…Sirtuin 2 (Sirt2) is known to negatively regulate anoxia‐reoxygenation injury in myoblasts. Because protein levels of Sirt2 are increased in…”
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Shikonin-induced necroptosis is enhanced by the inhibition of autophagy in non-small cell lung cancer cells by Kim, Hyo-Jin, Hwang, Ki-Eun, Park, Do-Sim, Oh, Seon-Hee, Jun, Hong Young, Yoon, Kwon-Ha, Jeong, Eun-Taik, Kim, Hak-Ryul, Kim, Young-Suk

“…Shikonin, a natural naphthoquinone pigment purified from Lithospermum erythrorhizon, induces necroptosis in various cancer types, but the mechanisms underlying…”
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Activation of AMPK by berberine induces hepatic lipid accumulation by upregulation of fatty acid translocase CD36 in mice by Choi, You-Jin, Lee, Kang-Yo, Jung, Seung-Hwan, Kim, Hyung Sik, Shim, Gayong, Kim, Mi-Gyeong, Oh, Yu-Kyoung, Oh, Seon-Hee, Jun, Dae Won, Lee, Byung-Hoon

“…Emerging evidence has shown that berberine has a protective effect against metabolic syndrome such as obesity and type II diabetes mellitus by activating…”
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Role of autophagy in chemoresistance: Regulation of the ATM-mediated DNA-damage signaling pathway through activation of DNA–PKcs and PARP-1 by Yoon, Jung-Hoon, Ahn, Sang-Gun, Lee, Byung-Hoon, Jung, Sung-Hoo, Oh, Seon-Hee

“…DNA-damage signaling pathway after genotoxic stress. Capsaicin-induced autophagy regulates the DNA-repair signaling pathway, thereby prolonging cancer cell…”
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Role of the AMPK/SREBP-1 pathway in the development of orotic acid-induced fatty liver by Jung, Eun-Jeong, Kwon, Sung-Won, Jung, Byung-Hwa, Oh, Seon-Hee, Lee, Byung-Hoon

“…Orotic acid (OA), an intermediate in pyrimidine metabolism, has been used for a variety of purposes, such as dietary supplements. Although it is well…”
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Autophagy regulated by prolyl isomerase Pin1 and phospho-Ser-GSK3αβ involved in protection of oral squamous cell carcinoma against cadmium toxicity by So, Keum-Young, Ahn, Sang-Gun, Oh, Seon-Hee

“…Prolyl isomerase Pin1 plays an important role in cell proliferation and is overexpressed in many human tumors. However, its role in autophagy induction remains…”
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Inhibition of autophagy potentiates pemetrexed and simvastatin-induced apoptotic cell death in malignant mesothelioma and non-small cell lung cancer cells by Hwang, Ki-Eun, Kim, Young-Suk, Jung, Jae-Wan, Kwon, Su-Jin, Park, Do-Sim, Cha, Byong-Ki, Oh, Seon-Hee, Yoon, Kwon-Ha, Jeong, Eun-Taik, Kim, Hak-Ryul

“…Pemetrexed, a multitarget antifolate used to treat malignant mesothelioma and non-small cell lung cancer (NSCLC), has been shown to stimulate autophagy. In…”
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Selective induction of catalase-mediated autophagy by dihydrocapsaicin in lung cell lines by Choi, Cheol-Hee, Jung, Yong-Keun, Oh, Seon-Hee

“…We reported that dihydrocapsaicin (DHC) induces autophagy in a catalase-regulated manner. In this study, we further examined the role of DHC-induced autophagy…”
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Autophagy involvement in cadmium resistance through induction of multidrug resistance-associated protein and counterbalance of endoplasmic reticulum stress WI38 lung epithelial fibroblast cells by Lim, Sung-Chul, Hahm, Kyung-Soo, Lee, Song-Hee, Oh, Seon-Hee

“…Abstract Human multidrug-resistance associated protein (MRP1) is known as a cellular efflux pump of heavy metals and anticancer drugs. In our previous study,…”
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Activation of autophagy rescues amiodarone-induced apoptosis of lung epithelial cells and pulmonary toxicity in rats by Lee, Kang-Yo, Oh, Sehee, Choi, You-Jin, Oh, Seon-Hee, Yang, Young-Su, Yang, Mi-Jin, Lee, Kyuhong, Lee, Byung-Hoon

“…Amiodarone, bi-iodinated benzofuran derivative, is one of the most frequently prescribed and efficacious antiarrhythmic drugs. Despite its low incidence,…”
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Nefopam downregulates autophagy and c-Jun N-terminal kinase activity in the regulation of neuropathic pain development following spinal nerve ligation by Oh, Seon-Hee, Yoon, Myung Ha, Lim, Kyung Joon, Yu, Byung Sik, Jee, In Gook, Jung, Ki Tae

“…Neurodegeneration is associated with changes in basal cellular function due to the dysregulation of autophagy. A recent study introduced the involvement of…”
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Dihydrocapsaicin (DHC), a saturated structural analog of capsaicin, induces autophagy in human cancer cells in a catalase-regulated manner by Oh, Seon Hee, Kim, Young Soon, Lim, Sung Chul, Hou, Yi Feng, Chang, In Youb, You, Ho Jin

“…Although capsaicin, a pungent component of red pepper, is known to induce apoptosis in several types of cancer cells, the mechanisms underlying…”
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Effect of sec-O-glucosylhamaudol on mechanical allodynia in a rat model of postoperative pain by Koh, Gi-Ho, Song, Hyun, Kim, Sang Hun, Yoon, Myung Ha, Lim, Kyung Joon, Oh, Seon-Hee, Jung, Ki Tae

“…This study was performed in order to examine the effect of intrathecal sec-O-glucosylhamaudol (SOG), an extract from the root of the Peucedanum japonicum…”
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Autophagy-mediated cytoplasmic accumulation of p53 leads to apoptosis through DRAM-BAX in cadmium-exposed human proximal tubular cells by Lee, Hyun-Young, Oh, Seon-Hee

“…The tumor suppressor p53 is involved in cadmium (Cd)-induced apoptosis and autophagy. However, the regulatory mechanisms of p53 in Cd-induced kidney injury are…”
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Arsenite-induced cytotoxicity is regulated by poly-ADP ribose polymerase 1 activation and parthanatos in p53-deficient H1299 cells: The roles of autophagy and p53 by So, Keum-Young, Oh, Seon-Hee

“…Arsenic is a double-edged sword metalloid since it is both an environmental carcinogen and a chemopreventive agent. Arsenic cytotoxicity can be dependent or…”
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