Search Results - "Oh, Seog Bae"

Natural Killer Cells Degenerate Intact Sensory Afferents following Nerve Injury by Davies, Alexander J., Kim, Hyoung Woo, Gonzalez-Cano, Rafael, Choi, Jahyang, Back, Seung Keun, Roh, Seung Eon, Johnson, Errin, Gabriac, Melanie, Kim, Mi-Sun, Lee, Jaehee, Lee, Jeong Eun, Kim, Yun Sook, Bae, Yong Chul, Kim, Sang Jeong, Lee, Kyung-Mi, Na, Heung Sik, Riva, Priscilla, Latremoliere, Alban, Rinaldi, Simon, Ugolini, Sophie, Costigan, Michael, Oh, Seog Bae

“…Sensory axons degenerate following separation from their cell body, but partial injury to peripheral nerves may leave the integrity of damaged axons preserved…”
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TRPV1 in GABAergic Interneurons Mediates Neuropathic Mechanical Allodynia and Disinhibition of the Nociceptive Circuitry in the Spinal Cord by Kim, Yong Ho, Back, Seung Keun, Davies, Alexander J., Jeong, Heejin, Jo, Hyun Jung, Chung, Geehoon, Na, Heung Sik, Bae, Yong Chul, Kim, Sang Jeong, Kim, Joong Soo, Jung, Sung Jun, Oh, Seog Bae

“…Neuropathic pain and allodynia may arise from sensitization of central circuits. We report a mechanism of disinhibition-based central sensitization resulting…”
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Clonidine, an alpha‐2 adrenoceptor agonist relieves mechanical allodynia in oxaliplatin‐induced neuropathic mice; potentiation by spinal p38 MAPK inhibition without motor dysfunction and hypotension by Yeo, Ji‐Hee, Yoon, Seo‐Yeon, Kim, Sol‐Ji, Oh, Seog‐Bae, Lee, Jang‐Hern, Beitz, Alvin J., Roh, Dae‐Hyun

“…Cancer chemotherapy with platinum‐based antineoplastic agents including oxaliplatin frequently results in a debilitating and painful peripheral neuropathy. We…”
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A Critical Role of Toll-like Receptor 2 in Nerve Injury-induced Spinal Cord Glial Cell Activation and Pain Hypersensitivity by Kim, Donghoon, Kim, Myung Ah, Cho, Ik-Hyun, Kim, Mi Sun, Lee, Soojin, Jo, Eun-Kyeong, Choi, Se-Young, Park, Kyungpyo, Kim, Joong Soo, Akira, Shizuo, Na, Heung Sik, Oh, Seog Bae, Lee, Sung Joong

“…The activation of spinal cord glial cells has been implicated in the development of neuropathic pain upon peripheral nerve injury. The molecular mechanisms…”
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Reduced acute nociception and chronic pain in Shank2−/− mice by Ko, Hyoung-Gon, Oh, Seog-Bae, Zhuo, Min, Kaang, Bong-Kiun

“…Autism spectrum disorder is a debilitating mental illness and social issue. Autism spectrum disorder patients suffer from social isolation, cognitive deficits,…”
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Recent advances in basic research on the trigeminal ganglion by Goto, Tetsuya, Oh, Seog Bae, Takeda, Mamoru, Shinoda, Masamichi, Sato, Tadasu, Gunjikake, Kaori K, Iwata, Koichi

“…Peripheral tissue inflammation can alter the properties of somatic sensory pathways, causing behavioral hypersensitivity and resulting in increased responses…”
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Spinal sigma-1 receptor activation increases the production of d-serine in astrocytes which contributes to the development of mechanical allodynia in a mouse model of neuropathic pain by Moon, Ji-Young, Choi, Sheu-Ran, Roh, Dae-Hyun, Yoon, Seo-Yeon, Kwon, Soon-Gu, Choi, Hoon-Seong, Kang, Suk-Yun, Han, Ho-Jae, Kim, Hyun-Woo, Beitz, Alvin J., Oh, Seog-Bae, Lee, Jang-Hern

“…[Display omitted] DAAO, d-amino acid oxidase; i.t., intrathecal; LSOS, l-serine O-sulfate potassium salt; NMDA R, N-methyl-d-aspartate receptor; Sig-1R,…”
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Involvement of cannabinoid type 1 receptor in fasting-induced analgesia by Lee, Jeong-Yun, Lee, Grace J., Nakamura, Ayumi, Lee, Pa Reum, Kim, Yeajin, Won, Chan Hee, Furue, Hidemasa, Oh, Seog Bae

“…The endocannabinoid system (ECS) is known to modulate not only food intake but also pain, especially via the cannabinoid type 1 receptor (CB1R) expressed…”
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Spinal sigma-1 receptors activate NADPH oxidase 2 leading to the induction of pain hypersensitivity in mice and mechanical allodynia in neuropathic rats by Choi, Sheu-Ran, Roh, Dae-Hyun, Yoon, Seo-Yeon, Kang, Suk-Yun, Moon, Ji-Young, Kwon, Soon-Gu, Choi, Hoon-Seong, Han, Ho-Jae, Beitz, Alvin J., Oh, Seog-Bae, Lee, Jang-Hern

“…We have recently demonstrated that spinal sigma-1 receptors (Sig-1Rs) mediate pain hypersensitivity in mice and neuropathic pain in rats. In this study, we…”
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Coapplication of Lidocaine and the Permanently Charged Sodium Channel Blocker QX-314 Produces a Long-lasting Nociceptive Blockade in Rodents by BINSHTOK, Alexander M, GERNER, Peter, MITANI, Aya A, GING KUO WANG, BEAN, Bruce P, WOOLF, Clifford J, BAE, Seog, PUOPOLO, Michelino, SUZUKI, Suzuko, ROBERSON, David P, HERBERT, Teri, WANG, Chi-Fei, KIM, Donghoon, CHUNG, Gehoon

“…Nociceptive-selective local anesthesia is produced by entry of the permanently charged lidocaine-derivative QX-314 into nociceptors when coadministered with…”
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Membrane-Delimited Coupling of TRPV1 and mGluR5 on Presynaptic Terminals of Nociceptive Neurons by Kim, Yong Ho, Park, Chul-Kyu, Back, Seung Keun, Lee, C. Justin, Hwang, Se Jin, Bae, Yong Chul, Na, Heung Sik, Kim, Joong Soo, Jung, Sung Jun, Oh, Seog Bae

“…Transient receptor potential vanilloid subtype 1 (TRPV1) and metabotropic glutamate receptor 5 (mGluR5) located on peripheral sensory terminals have been shown…”
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Inhibition of mechanical allodynia in neuropathic pain by TLR5-mediated A-fiber blockade by Xu, Zhen-Zhong, Kim, Yong Ho, Bang, Sangsu, Zhang, Yi, Berta, Temugin, Wang, Fan, Oh, Seog Bae, Ji, Ru-Rong

“…Toll-like receptor 5 (TLR5) expression is found to be enriched in mouse dorsal root ganglion (DRG) A-fiber neurons known to mediate mechanical allodynia, a…”
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Histamine H1 receptor induces cytosolic calcium increase and aquaporin translocation in human salivary gland cells by Kim, Ji-Hyun, Park, Seong-Hae, Moon, Young Wha, Hwang, Sungmin, Kim, Donghoon, Jo, Su-Hyun, Oh, Seog Bae, Kim, Joong Soo, Jahng, Jeong Won, Lee, Jong-Ho, Lee, Sung Joong, Choi, Se-Young, Park, Kyungpyo

“…One of the common side effects of antihistamine medicines is xerostomia (dry mouth). The current consensus is that antihistamine-induced xerostomia comes from…”
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Requirement of homotypic NK-cell interactions through 2B4(CD244)/CD48 in the generation of NK effector functions by Lee, Kyung-Mi, Forman, John P., McNerney, Megan E., Stepp, Susan, Kuppireddi, Sumalatha, Guzior, Dustin, Latchman, Yvette E., Sayegh, Mohamed H., Yagita, Hideo, Park, Chul-Kyu, Oh, Seog Bae, Wülfing, Christoph, Schatzle, John, Mathew, Porunelloor A., Sharpe, Arlene H., Kumar, Vinay

“…2B4 belongs to the CD2 subset of the IgG family of receptors. Members in this family have been shown to function as coreceptors via homophilic or heterophilic…”
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Molecular Basis of Cav2.3 Calcium Channels in Rat Nociceptive Neurons by Fang, Zhi, Park, Chul-Kyu, Li, Hai Ying, Kim, Hyun Yeong, Park, Seong-Hae, Jung, Sung Jun, Kim, Joong Soo, Monteil, Arnaud, Oh, Seog Bae, Miller, Richard J.

“…Cav2.3 calcium channels play an important role in pain transmission in peripheral sensory neurons. Six Cav2.3 isoforms resulting from different combinations of…”
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Cytotoxic Immunity in Peripheral Nerve Injury and Pain by Davies, Alexander J, Rinaldi, Simon, Costigan, Michael, Oh, Seog Bae

“…Cytotoxicity and consequent cell death pathways are a critical component of the immune response to infection, disease or injury. While numerous examples of…”
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Acquisition of in vitro and in vivo functionality of Nurr1‐induced dopamine neurons by Park, Chang‐Hwan, Kang, Jin Sun, Ho Shin, Yeon, Chang, Mi‐Yoon, Chung, Seungsoo, Koh, Hyun‐Chul, Zhu, Mei Hong, Bae Oh, Seog, Lee, Yong‐Sung, Panagiotakos, Georgia, Tabar, Vivian, Studer, Lorenz, Lee, Sang‐Hun

“…Neural precursor cells provide an expandable source of neurons and glia for basic and translational applications. However, little progress has been made in…”
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Experience-dependent modification of mechanisms of long-term depression by Cho, Kwangwook, Jo, Jihoon, Ball, Simon M, Seok, Heon, Oh, Seog Bae, Massey, Peter V, Molnar, Elek, Bashir, Zafar I

“…Mechanisms of long-term potentiation and depression (LTP and LTD) change considerably during development, but the importance of these changes and the factors…”
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Alpha 2 adrenoceptor agonist guanabenz directly inhibits hyperpolarization-activated, cyclic nucleotide-modulated (HCN) channels in mesencephalic trigeminal nucleus neurons by Won, Jonghwa, Lee, Pa Reum, Oh, Seog Bae

“…Alpha 2 (α2-) adrenoceptor agonists, such as clonidine or dexmedetomidine, have been found to inhibit hyperpolarization-activated, cyclic nucleotide-modulated…”
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Molecular expression of Mg2+ regulator TRPM7 and CNNM4 in rat odontoblasts by Won, Jonghwa, Kim, Ji Hyun, Oh, Seog Bae

“…•CNNM4 is mainly expressed in TRPM7-positive odontoblasts.•TRPM7 is ubiquitously expressed along the odontoblastic layer.•CNNM4 is preferentially expressed in…”
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