Search Results - "Oh, Seh–Hoon"

Connective tissue growth factor and integrin αvβ6: A new pair of regulators critical for ductular reaction and biliary fibrosis in mice by Pi, Liya, Robinson, Paulette M., Jorgensen, Marda, Oh, Seh‐Hoon, Brown, Alicia R., Weinreb, Paul H., Trinh, Thu Le, Yianni, Protopapadakis, Liu, Chen, Leask, Andrew, Violette, Shelia M., Scott, Edward W., Schultz, Gregory S., Petersen, Bryon E.

“…Connective tissue growth factor (CTGF) is a matricellular protein that mediates cell‐matrix interaction through various subtypes of integrin receptors. This…”
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Granulocyte–Colony Stimulating Factor Promotes Liver Repair and Induces Oval Cell Migration and Proliferation in Rats by Piscaglia, Anna C, Shupe, Thomas D, Oh, Seh–Hoon, Gasbarrini, Antonio, Petersen, Bryon E

“…Background & Aims: Hepatic regeneration is a heterogeneous phenomenon involving several cell populations. Oval cells are considered liver stem cells, a portion…”
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Bone Marrow–Derived Hepatic Oval Cells Differentiate Into Hepatocytes in 2-Acetylaminofluorene/Partial Hepatectomy–Induced Liver Regeneration by Oh, Seh–Hoon, Witek, Rafal P, Bae, Si–Hyun, Zheng, Donghang, Jung, Youngmi, Piscaglia, Anna C, Petersen, Bryon E

“…Background & Aims: The ability of the bone marrow cells to differentiate into liver, pancreas, and other tissues led to the speculation that these cells might…”
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Teratoma Formation Leads to Failure of Treatment for Type I Diabetes Using Embryonic Stem Cell-Derived Insulin-Producing Cells by Fujikawa, Takahisa, Oh, Seh-Hoon, Pi, Liya, Hatch, Heather M., Shupe, Tom, Petersen, Bryon E.

“…Embryonic stem (ES) cells have been proposed to be a powerful tool in the study of pancreatic disease, as well as a potential source for cell replacement…”
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RNA Binding Proteins Control Transdifferentiation of Hepatic Stellate Cells into Myofibroblasts by Wang, Sihyung, Jung, Youngmi, Hyun, Jeongeun, Friedersdorf, Matthew, Oh, Seh-Hoon, Kim, Jieun, Premont, Richard T., Keene, Jack D., Diehl, Anna Mae

“…Abstract Background/Aims: Myofibroblasts (MF) derived from quiescent nonfibrogenic hepatic stellate cells (HSC) are the major sources of fibrous matrix in…”
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Tumor necrosis factor-inducible gene 6 protein ameliorates chronic liver damage by promoting autophagy formation in mice by Wang, Sihyung, Lee, Chanbin, Kim, Jieun, Hyun, Jeongeun, Lim, Minso, Cha, Hyuk-Jin, Oh, Seh-Hoon, Choi, Yung Hyun, Jung, Youngmi

“…Tumor necrosis factor-inducible gene 6 protein (TSG-6) has recently been shown to protect the liver from acute damage. However, the mechanism underlying the…”
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Connective tissue growth factor with a novel fibronectin binding site promotes cell adhesion and migration during rat oval cell activation by Pi, Liya, Ding, Xiaodong, Jorgensen, Marda, Pan, Jen‐Jung, Oh, Seh‐Hoon, Pintilie, Dana, Brown, Alicia, Song, Wen‐Yuan, Petersen, Bryon E.

“…Oval cell activation, as part of the regenerative process after liver injury, involves considerable cell‐matrix interaction. The matricellular protein,…”
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Hepatocyte activity of the cholesterol sensor smoothened regulates cholesterol and bile acid homeostasis in mice by Dalton, George D., Oh, Seh-Hoon, Tang, Linda, Zhang, Stephanie, Brown, Amanda L., Varadharajan, Venkateshwari, Baleanu-Gogonea, Camelia, Gogonea, Valentin, Pathak, Preeti, Brown, J. Mark, Diehl, Anna Mae

“…Cellular cholesterol is regulated by at least two transcriptional mechanisms involving sterol-regulatory-element-binding proteins (SREBPs) and liver X…”
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Liver regeneration requires Yap1-TGFβ-dependent epithelial-mesenchymal transition in hepatocytes by Oh, Seh-Hoon, Swiderska-Syn, Marzena, Jewell, Mark L., Premont, Richard T., Diehl, Anna Mae

“…[Display omitted] •During liver regeneration, hepatocytes transiently proliferate despite active TGFβ signaling.•Regenerating hepatocytes reduce epithelial…”
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Syngeneic Myoblast Transplantation Improves Muscle Function in a Murine Model of X-Linked Myotubular Myopathy by Lim, Hyun Ju, Joo, Sunyoung, Oh, Seh-Hoon, Jackson, John D, Eckman, Delrae M, Bledsoe, Tiffaney M, Pierson, Christopher R, Childers, Martin K, Atala, Anthony, Yoo, James J

“…X-linked myotubular myopathy (XLMTM) is an isogenic muscle disease characterized by progressive wasting of skeletal muscle, weakness, and premature death of…”
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Role of Connective Tissue Growth Factor in Oval Cell Response During Liver Regeneration After 2-AAF/PHx in Rats by Pi, Liya, Oh, Seh-Hoon, Shupe, Thomas, Petersen, Bryon E.

“…Background & Aims: Recruitment and proliferation of Thy-1 + oval cells is a hallmark of liver regeneration after 2-acetylaminofluorene (2-AAF)/partial…”
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Somatostatin stimulates the migration of hepatic oval cells in the injured rat liver by Jung, Youngmi, Oh, Seh-Hoon, Witek, Rafal P., Petersen, Bryon E.

“…Background Somatostatin is a pleiotropic peptide, exerting a variety of effects through its receptor subtypes. Recently, somatostatin has been shown to act as…”
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Oval Cell Response in 2-Acetylaminofluorene/Partial Hepatectomy Rat Is Attenuated by Short Interfering RNA Targeted to Stromal Cell-Derived Factor-1 by Zheng, Donghang, Oh, Seh-hoon, Jung, Youngmi, Petersen, Bryon E.

“…Stromal cell-derived factor-1 (SDF-1) is known to play an essential role in the regulation of stem/progenitor cell trafficking. During hepatic stem, or oval,…”
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Tumor necrosis factor-inducible gene 6 reprograms hepatic stellate cells into stem-like cells, which ameliorates liver damage in mouse by Wang, Sihyung, Kim, Jieun, Lee, Chanbin, Oh, Dayoung, Han, Jinsol, Kim, Tae-Jin, Kim, Sang-Woo, Seo, Young-Su, Oh, Seh-hoon, Jung, Youngmi

“…Liver fibrosis is a major characteristic of liver disease. When the liver is damaged, quiescent hepatic stellate cells (HSCs) transdifferentiate into…”
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Dysregulation of the ESRP2-NF2-YAP/TAZ axis promotes hepatobiliary carcinogenesis in non-alcoholic fatty liver disease by Hyun, Jeongeun, Al Abo, Muthana, Dutta, Rajesh Kumar, Oh, Seh Hoon, Xiang, Kun, Zhou, Xiyou, Maeso-Díaz, Raquel, Caffrey, Rebecca, Sanyal, Arun J., Freedman, Jennifer A., Patierno, Steven R., Moylan, Cynthia A., Abdelmalek, Manal F., Diehl, Anna Mae

“…Non-alcoholic fatty liver disease (NAFLD), the hepatic correlate of the metabolic syndrome, is a major risk factor for hepatobiliary cancer (HBC). Although…”
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Dysregulated activation of fetal liver programme in acute liver failure by Hyun, Jeongeun, Oh, Seh-Hoon, Premont, Richard T, Guy, Cynthia D, Berg, Carl L, Diehl, Anna Mae

“…Uncertainty about acute liver failure (ALF) pathogenesis limits therapy. We postulate that ALF results from excessive reactivation of a fetal liver programme…”
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Real-time imaging of de novo arteriovenous malformation in a mouse model of hereditary hemorrhagic telangiectasia by Park, Sung Ok, Wankhede, Mamta, Lee, Young Jae, Choi, Eun-Jung, Fliess, Naime, Choe, Se-Woon, Oh, Seh-Hoon, Walter, Glenn, Raizada, Mohan K, Sorg, Brian S, Oh, S Paul

“…Arteriovenous malformations (AVMs) are vascular anomalies where arteries and veins are directly connected through a complex, tangled web of abnormal arteries…”
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Low prevalence of HBV DNA in the liver allograft from anti-HBc-positive donors: a single-center experience by Pan, Jen-Jung, Oh, Seh-Hoon, Soldevila-Pico, Consuelo, Nelson, David R., Liu, Chen

“…Pan J‐J, Oh S‐H, Soldevila‐Pico C, Nelson DR, Liu C. Low prevalence of HBV DNA in the liver allograft from anti‐HBc‐positive donors: a single‐center…”
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A humanized mouse model for adeno-associated viral gene therapy by Barzi, Mercedes, Chen, Tong, Gonzalez, Trevor J., Pankowicz, Francis P., Oh, Seh Hoon, Streff, Helen L., Rosales, Alan, Ma, Yunhan, Collias, Sabrina, Woodfield, Sarah E., Diehl, Anna Mae, Vasudevan, Sanjeev A., Galvan, Thao N., Goss, John, Gersbach, Charles A., Bissig-Choisat, Beatrice, Asokan, Aravind, Bissig, Karl-Dimiter

“…Clinical translation of AAV-mediated gene therapy requires preclinical development across different experimental models, often confounded by variable…”
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The effect of collagen hydrogel on 3D culture of ovarian follicles by Joo, Sunyoung, Oh, Seh-Hoon, Sittadjody, Sivanandane, Opara, Emmanual C, Jackson, John D, Lee, Sang Jin, Yoo, James J, Atala, Anthony

“…The in vivo function and phenotype of ovarian follicle cells are determined by many factors. When these cells are removed from the in vivo microenvironment and…”
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