Search Results - "Oh, Kyu Hee"
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BTB Domain-containing Speckle-type POZ Protein (SPOP) Serves as an Adaptor of Daxx for Ubiquitination by Cul3-based Ubiquitin Ligase
Published in The Journal of biological chemistry (05-05-2006)“…Daxx is a multifunctional protein that regulates a variety of cellular processes, including transcription, cell cycle, and apoptosis. SPOP is a BTB…”
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Modification of DBC1 by SUMO2/3 is crucial for p53-mediated apoptosis in response to DNA damage
Published in Nature communications (18-11-2014)“…DBC1 is a major inhibitor of SIRT1, which plays critical roles in the control of diverse cellular processes, including stress response and energy metabolism…”
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Chemosensitivity is controlled by p63 modification with ubiquitin-like protein ISG15
Published in The Journal of clinical investigation (01-07-2012)“…Identification of the cellular mechanisms that mediate cancer cell chemosensitivity is important for developing new cancer treatment strategies. Several…”
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c-Cbl regulates αPix-mediated cell migration and invasion
Published in Biochemical and biophysical research communications (12-12-2014)“…•c-Cbl ubiquitinates αPix for proteasome-mediated degradation.•C6 and A172 glioma cells lack c-Cbl, which leads to stabilization of αPix.•The accumulated αPix…”
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ISG15 modification of filamin B negatively regulates the type I interferon-induced JNK signalling pathway
Published in EMBO reports (01-04-2009)“…Interferon (IFN)‐induced signalling pathways have essential functions in innate immune responses. In response to type I IFNs, filamin B tethers RAC1 and a Jun…”
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USP47 and C terminus of Hsp70-interacting protein (CHIP) antagonistically regulate katanin-p60-mediated axonal growth
Published in The Journal of neuroscience (31-07-2013)“…Katanin is a heterodimeric enzyme that severs and disassembles microtubules. While the p60 subunit has the enzyme activity, the p80 subunit regulates the p60…”
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CHIP E3 Ligase and USP2 Deubiquitinating Enzyme Antagonistically Control AIF‐mediated Programmed Cell Death
Published in The FASEB journal (01-04-2010)“…Under normal conditions, apoptosis inducing factor (AIF) in the mitochondrial membrane functions as an oxidoreductase that scavenges reactive oxygen species…”
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Chemosensitivity is controlled by p63 modification with ubiquitin-like protein ISG 15
Published in The Journal of clinical investigation (01-07-2012)“…Identification of the cellular mechanisms that mediate cancer cell chemosensitivity is important for developing new cancer treatment strategies. Several…”
Get full text
Journal Article