Search Results - "Oh, Hye Jwa"
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Interleukin-22 promotes osteoclastogenesis in rheumatoid arthritis through induction of RANKL in human synovial fibroblasts
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-04-2012)“…Objective To examine the regulatory role of interleukin‐22 (IL‐22) in the expression of RANKL and induction of osteoclastogenesis in rheumatoid arthritis (RA)…”
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2
Epigallocatechin‐3‐gallate ameliorates autoimmune arthritis by reciprocal regulation of T helper‐17 regulatory T cells and inhibition of osteoclastogenesis by inhibiting STAT3 signaling
Published in Journal of leukocyte biology (01-09-2016)“…EGCG attenuates arthritis and osteoclastogenesis by inhibition of Th17 and reciprocal induction of Treg. The green tea polyphenol epigallocatechin‐3‐gallate is…”
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3
Retinoic acid attenuates rheumatoid inflammation in mice
Published in The Journal of immunology (1950) (15-07-2012)“…Retinoic acid is the active vitamin A derivative and is well-known to have diverse immunomodulatory actions. In this study, we investigated the impact of…”
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4
IL-17-mediated Bcl-2 expression regulates survival of fibroblast-like synoviocytes in rheumatoid arthritis through STAT3 activation
Published in Arthritis research & therapy (20-02-2013)“…Fibroblast-like synoviocytes (FLSs) are a major cell population of the pannus that invades adjacent cartilage and bone in rheumatoid arthritis (RA). The study…”
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Modulation of STAT-3 in rheumatoid synovial T cells suppresses Th17 differentiation and increases the proportion of Treg cells
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-11-2012)“…Objective To investigate the impact of STAT‐3–mediated regulation on Th17 differentiation in patients with rheumatoid arthritis (RA). Methods CD4+ T cells…”
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Interleukin‐2/anti‐interleukin‐2 monoclonal antibody immune complex suppresses collagen‐induced arthritis in mice by fortifying interleukin‐2/STAT5 signalling pathways
Published in Immunology (01-12-2012)“…Summary In this study, we investigated the effects of administration of interleukin‐2 (IL‐2)/JES6‐1 (anti‐IL‐2 monoclonal antibody) immune complexes on the…”
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7
IL-12p40 Homodimer Ameliorates Experimental Autoimmune Arthritis
Published in The Journal of immunology (1950) (01-10-2015)“…IL-23 is the key cytokine that induces the expansion of Th17 cells. It is composed of p19 and p40 subunits of IL-12. The p40 subunit binds competitively to the…”
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8
Grape seed proanthocyanidin extract ameliorates monosodium iodoacetate-induced osteoarthritis
Published in Experimental & molecular medicine (31-10-2011)“…Osteoarthritis (OA) is an age-related joint disease that is characterized by degeneration of articular cartilage and chronic pain. Oxidative stress is…”
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9
Regulation of B cell activating factor (BAFF) receptor expression by NF-κB signaling in rheumatoid arthritis B cells
Published in Experimental & molecular medicine (30-06-2011)“…B cells play an important role in the pathogenesis of rheumatoid arthritis (RA). High levels of B cell activating factor (BAFF) are detected in autoimmune…”
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10
Expression of TLR2, TLR4, and TLR9 in dermatomyositis and polymyositis
Published in Clinical rheumatology (01-03-2010)“…The aim of this study was to investigate the expressions of Toll-like receptor (TLR) 2, TLR4, TLR9, and their correlations with the expression of cytokines…”
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11
Grape seed proanthocyanidin extract (GSPE) attenuates collagen-induced arthritis
Published in Immunology letters (04-06-2009)“…Abstract To examine whether grape seed proanthocyanidin extract (GSPE) which is known to act as an antioxidant has therapeutic effect on collagen-induced…”
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12
IL-17 increases cadherin-11 expression in a model of autoimmune experimental arthritis and in rheumatoid arthritis
Published in Immunology letters (30-10-2011)“…Highlights ► The IL-17 activated RA FLS to express cadherin-11 which is mediated by NF-κB signaling. ► IL-17 aggravated joint inflammation, bone destruction…”
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13
Engagement of toll-like receptor 3 induces vascular endothelial growth factor and interleukin-8 in human rheumatoid synovial fibroblasts
Published in The Korean journal of internal medicine (01-12-2010)“…Angiogenesis, which is a critical step in the initiation and progression of rheumatoid arthritis (RA), involves pro-angiogenic factors, including interleukin…”
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14
Myeloid differentiation primary response protein 88 blockade upregulates indoleamine 2,3-dioxygenase expression in rheumatoid synovial fibroblasts
Published in Experimental & molecular medicine (2011)“…Indoleamine 2,3-dioxygenase (IDO) is a key negative regulator of immune responses and has been implicated in tumor tolerance, autoimmune disease and asthma…”
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15
IL-10 suppresses Th17 cells and promotes regulatory T cells in the CD4+ T cell population of rheumatoid arthritis patients
Published in Immunology letters (04-01-2010)“…Abstract Interleukin-17-producing CD4+ T cells (Th17 cells) are the dominant pathogenic cellular component in autoimmune inflammatory diseases, including…”
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Measurement of interleukin-33 (IL-33) and IL-33 receptors (sST2 and ST2L) in patients with rheumatoid arthritis
Published in Journal of Korean medical science (01-09-2011)“…The interleukin-33 (IL-33)/ST2 pathway has emerged as an intercellular signaling system that participates in antigen-allergen response, autoimmunity and…”
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TWEAK promotes the production of Interleukin-17 in rheumatoid arthritis
Published in Cytokine (Philadelphia, Pa.) (01-10-2012)“…Tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK) is an inflammatory cytokine that modulates several biological responses by inducing…”
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Amelioration of autoimmune arthritis by adoptive transfer of Foxp3-expressing regulatory B cells is associated with the Treg/Th17 cell balance
Published in Journal of translational medicine (28-06-2016)“…Foxp3 is a key regulator of the development and function of regulatory T cells (Tregs), and its expression is thought to be T cell-restricted. We found that B…”
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CTLA4-Ig modifies dendritic cells from mice with collagen-induced arthritis to increase the CD4+CD25+Foxp3+ regulatory T cell population
Published in Journal of autoimmunity (01-03-2010)“…Abstract Cytotoxic T lymphocyte antigen-4 (CTLA4) and IgG fusion protein, CTLA4-Ig, is a therapeutic agent used for rheumatoid arthritis. It binds B7 molecules…”
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Myeloid differentiation primary response protein 88 blockade upregulates indoleamine 2,3-dioxygenase expression in rheumatoid synovial fibroblasts
Published in Experimental & molecular medicine (2011)“…Indoleamine 2,3-dioxygenase (IDO) is a key negative regulator of immune responses and has been implicated in tumor tolerance, autoimmune disease and asthma…”
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