Search Results - "Oh, Heeseung"
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DEL-1: a promising treatment for AMD-associated ER stress in retinal pigment epithelial cells
Published in Journal of translational medicine (09-01-2024)“…Age-related macular degeneration (AMD) is an irreversible eye disease that can cause blurred vision. Regular exercise has been suggested as a therapeutic…”
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Ginsenoside Rb3 ameliorates podocyte injury under hyperlipidemic conditions via PPARδ- or SIRT6-mediated suppression of inflammation and oxidative stress
Published in Journal of ginseng research (01-05-2023)“…Rb3 is a ginsenoside with anti-inflammatory properties in many cell types and has been reported to attenuate inflammation-related metabolic diseases such as…”
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The aqueous extract of Phragmites rhizome improves hepatic steatosis in obese mice via the AMPK-mediated inhibition of ER stress
Published in Journal of functional foods (01-08-2022)“…[Display omitted] •The aqueous extract of Phragmites rhizome (AP) suppresses ER stress in hepatocytes under hyperlipidemic conditions.•AP ameliorates hepatic…”
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Developmental endothelial locus-1 attenuates palmitate-induced apoptosis in tenocytes through the AMPK/autophagy-mediated suppression of inflammation and endoplasmic reticulum stress
Published in Bone & joint research (01-12-2022)“…Myokine developmental endothelial locus-1 (DEL-1) has been documented to alleviate inflammation and endoplasmic reticulum (ER) stress in various cell types…”
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Resolvin D3 improves the impairment of insulin signaling in skeletal muscle and nonalcoholic fatty liver disease through AMPK/autophagy-associated attenuation of ER stress
Published in Biochemical pharmacology (01-09-2022)“…[Display omitted] Resolvin D3 (RD3), an endogenous lipid mediator derived from omega-3 fatty acids, has been documented to attenuate inflammation in various…”
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Interleukin-27 as a novel player in alleviating hepatic steatosis: Mechanistic insights from an in vitro analysis
Published in Biochemical and biophysical research communications (09-04-2024)“…Interleukin-27 (IL-27) is a recently discovered cytokine that has been implicated in inflammatory and metabolic conditions, such as atherosclerosis and insulin…”
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Madecassoside ameliorates hepatic steatosis in high-fat diet-fed mice through AMPK/autophagy-mediated suppression of ER stress
Published in Biochemical pharmacology (01-11-2023)“…[Display omitted] Hepatic endoplasmic reticulum (ER) stress is a contributing factor in the development of hepatic steatosis in obesity. Madecassoside (MA), a…”
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Sclerostin aggravates insulin signaling in skeletal muscle and hepatic steatosis via upregulation of ER stress by mTOR‐mediated inhibition of autophagy under hyperlipidemic conditions
Published in Journal of cellular physiology (01-11-2022)“…Recently, sclerostin (SCL), a circulating glycoprotein, was proposed to be a novel myokine involved in developing metabolic disorders. The association between…”
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Musclin attenuates lipid deposition in hepatocytes through SIRT7/autophagy-mediated suppression of ER stress
Published in Biochemical and biophysical research communications (28-05-2023)“…Musclin, an exercise-responsive myokine, has the ability to attenuate inflammation, oxidative stress, and apoptosis in cardiomyocytes under pathogenic…”
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CTRP4 attenuates apoptosis and epithelial-mesenchymal transition markers in podocytes through an AMPK/autophagy-dependent pathway
Published in Biochemical and biophysical research communications (19-11-2023)“…Hyperglycemia, characterized by high blood glucose levels resulting from pancreatic beta cell dysfunction or impaired insulin signaling, is a contributing…”
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IL-38 alleviates atherogenic responses via SIRT6/HO-1 signaling: A promising strategy against obesity-related atherosclerosis
Published in Biochemical and biophysical research communications (29-01-2024)“…Interleukin-38 (IL-38), a member of the IL-1 family, is known for its anti-inflammatory properties mediated through ligand signaling in various disease models…”
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Myokine musclin alleviates lipid accumulation in 3T3-L1 adipocytes through PKA/p38-mediated upregulation of lipolysis and suppression of lipogenesis
Published in Biochemical and biophysical research communications (29-01-2023)“…Musclin (MUS), an exercise-responsive myokine, has been documented to attenuate inflammation and enhance physical endurance. However, the effects of MUS on…”
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CTRP4 ameliorates inflammation, thereby attenuating the interaction between HUVECs and THP-1 monocytes through SIRT6/Nrf2 signaling
Published in Biochemical and biophysical research communications (08-01-2024)“…CTRP4, identified as an adipokine, has demonstrated notable anti-inflammatory and anti-obesity effects in various disease models. Consequently, our research…”
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Oroxylin-A alleviates hepatic lipid accumulation and apoptosis under hyperlipidemic conditions via AMPK/FGF21 signaling
Published in Biochemical and biophysical research communications (12-03-2023)“…Oroxylin-A (OA) is an O-methylated flavone that has been demonstrated to have anti-inflammatory properties in various disease models. However, the roles of OA…”
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Abietic acid alleviates endoplasmic reticulum stress and lipid accumulation in human primary hepatocytes through the AMPK/ORP150 signaling
Published in Biochemical and biophysical research communications (11-06-2022)“…Abietic acid (AA), the main component of pine resin that has been traditionally used as Asian medicine, has been reported to demonstrate anti-inflammatory…”
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Interleukin‐38 alleviates hepatic steatosis through AMPK/autophagy‐mediated suppression of endoplasmic reticulum stress in obesity models
Published in Journal of cellular physiology (01-04-2024)“…Interleukin‐38 (IL‐38), recently recognized as a cytokine with anti‐inflammatory properties that mitigate type 2 diabetes, has been associated with indicators…”
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Adipokine gremlin‐1 promotes hepatic steatosis via upregulation of ER stress by suppressing autophagy‐mediated signaling
Published in Journal of cellular physiology (01-05-2023)“…Gremlin‐1 (GR1) is a novel adipokine that is highly expressed in human adipocytes and has been shown to inhibit the BMP2/4‐TGFb signaling pathway. It has an…”
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Netrin-1 attenuates hepatic steatosis via UNC5b/PPARγ-mediated suppression of inflammation and ER stress
Published in Life sciences (1973) (15-12-2022)“…The current study investigated whether netrin-1 can attenuate hepatic steatosis through PPARγ/autophagy-mediated suppression of inflammation and endoplasmic…”
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Therapeutic potential of ginsenoside compound K in managing tenocyte apoptosis and extracellular matrix damage in diabetic tendinopathy
Published in Tissue & cell (01-02-2024)“…The prevalence of tendinopathy in patients with diabetes is well documented. Despite efforts to improve diabetes management, there is a lack of research on…”
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Ginsenoside Rb3 ameliorates podocyte injury under hyperlipidemic conditions via PPAR - or SIRT6-mediated suppression of infl ammation and oxidative stress
Published in Journal of ginseng research (01-05-2023)“…Background: Rb3 is a ginsenoside with anti-inflammatory properties in many cell types and has beenreported to attenuate inflammation-related metabolic diseases…”
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