Search Results - "Oh, Hakjin"
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An early endosome regulator, Rab5b, is an LRRK2 kinase substrate
Published in Journal of biochemistry (Tokyo) (01-06-2015)“…Leucine-rich repeat kinase 2 (LRRK2) has been identified as a causative gene for Parkinson's disease (PD). LRRK2 contains a kinase and a GTPase domain, both of…”
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Journal Article -
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Increase in anti-apoptotic molecules, nucleolin, and heat shock protein 70, against upregulated LRRK2 kinase activity
Published in Animal cells and systems (03-09-2018)“…Leucine-rich repeat kinase 2 (LRRK2) is involved in Parkinson's disease (PD) pathology. A previous study showed that rotenone treatment induced apoptosis,…”
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LRRK2 phosphorylates Snapin and inhibits interaction of Snapin with SNAP-25
Published in Experimental & molecular medicine (16-08-2013)“…Leucine-rich repeat kinase 2 ( LRRK2 ) is a gene that, upon mutation, causes autosomal-dominant familial Parkinson’s disease (PD). Yeast two-hybrid screening…”
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Journal Article