Search Results - "Oguro‐Ando, Asami"

Functional characterization of the schizophrenia associated gene AS3MT identifies a role in neuronal development by Washer, Sam J., Flynn, Robert, Oguro‐Ando, Asami, Hannon, Eilis, Burrage, Joe, Jeffries, Aaron, Mill, Jonathan, Dempster, Emma L.

“…Genome‐wide association studies (GWAS) have identified multiple genomic regions associated with schizophrenia, although many variants reside in noncoding…”
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Cntn4, a risk gene for neuropsychiatric disorders, modulates hippocampal synaptic plasticity and behavior by Oguro-Ando, Asami, Bamford, Rosemary A., Sital, Wiedjai, Sprengers, Jan J., Zuko, Amila, Matser, Jolien M., Oppelaar, Hugo, Sarabdjitsingh, Angela, Joëls, Marian, Burbach, J. Peter. H., Kas, Martien J.

“…Neurodevelopmental and neuropsychiatric disorders, such as autism spectrum disorders (ASD), anorexia nervosa (AN), Alzheimer’s disease (AD), and schizophrenia…”
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A novel method for generating glutamatergic SH-SY5Y neuron-like cells utilizing B-27 supplement by Martin, Emily-Rose, Gandawijaya, Josan, Oguro-Ando, Asami

“…The human SH-SY5Y neuroblastoma cell line is widely used in neuroscience research as a neuronal cell model. Following differentiation to a neuron-like state,…”
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Neuronal Cell Adhesion Molecules May Mediate Neuroinflammation in Autism Spectrum Disorder by Eve, Madeline, Gandawijaya, Josan, Yang, Liming, Oguro-Ando, Asami

“…Autism spectrum disorder (ASD) is a complex neurodevelopmental condition characterized by restrictive and repetitive behaviors, alongside deficits in social…”
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Regulation of astrocyte metabolism by mitochondrial translocator protein 18 kDa by Firth, Wyn, Robb, Josephine L., Stewart, Daisy, Pye, Katherine R., Bamford, Rosemary, Oguro‐Ando, Asami, Beall, Craig, Ellacott, Kate L. J.

“…The mitochondrial translocator protein 18 kDa (TSPO) has been linked to functions from steroidogenesis to regulation of cellular metabolism and is an…”
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Cell Adhesion Molecules Involved in Neurodevelopmental Pathways Implicated in 3p-Deletion Syndrome and Autism Spectrum Disorder by Gandawijaya, Josan, Bamford, Rosemary A, Burbach, J Peter H, Oguro-Ando, Asami

“…Autism spectrum disorder (ASD) is characterized by impaired social interaction, language delay and repetitive or restrictive behaviors. With increasing…”
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CD38 is Required for Dendritic Organization in Visual Cortex and Hippocampus by Nelissen, Thom P., Bamford, Rosemary A., Tochitani, Shiro, Akkus, Kamuran, Kudzinskas, Aurimas, Yokoi, Kenichiro, Okamoto, Hiroshi, Yamamoto, Yasuhiko, Burbach, J. Peter H., Matsuzaki, Hideo, Oguro-Ando, Asami

“…•Brain pathology and neuronal morphology of CD38-deficient mice are studied.•Cux1-positive cell numbers in layer II-IV of visual cortex are significantly…”
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Genetic Mapping in Mice Reveals the Involvement of Pcdh9 in Long-Term Social and Object Recognition and Sensorimotor Development by Bruining, Hilgo, Matsui, Asuka, Oguro-Ando, Asami, Kahn, René S, van‘t Spijker, Heleen M, Akkermans, Guus, Stiedl, Oliver, van Engeland, Herman, Koopmans, Bastijn, van Lith, Hein A, Oppelaar, Hugo, Tieland, Liselotte, Nonkes, Lourens J, Yagi, Takeshi, Kaneko, Ryosuke, Burbach, J. Peter H, Yamamoto, Nobuhiko, Kas, Martien J

“…Abstract Background Quantitative genetic analysis of basic mouse behaviors is a powerful tool to identify novel genetic phenotypes contributing to…”
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CNTN4 modulates neural elongation through interplay with APP by Bamford, Rosemary A, Zuko, Amila, Eve, Madeline, Sprengers, Jan J, Post, Harm, Taggenbrock, Renske L R E, Fäβler, Dominique, Mehr, Annika, Jones, Owen J R, Kudzinskas, Aurimas, Gandawijaya, Josan, Müller, Ulrike C, Kas, Martien J H, Burbach, J Peter H, Oguro-Ando, Asami

“…The neuronal cell adhesion molecule contactin-4 ( ) is genetically associated with autism spectrum disorder (ASD) and other psychiatric disorders. -deficient…”
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Developmental role of the cell adhesion molecule Contactin-6 in the cerebral cortex and hippocampus by Zuko, Amila, Oguro-Ando, Asami, van Dijk, Roland, Gregorio-Jordan, Sara, van der Zwaag, Bert, Burbach, J. Peter H.

“…The gene encoding the neural cell adhesion molecule Contactin-6 (Cntn6 a.k.a. NB-3) has been implicated as an autism risk gene, suggesting that its mutation is…”
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Association of Cell Adhesion Molecules Contactin-6 and Latrophilin-1 Regulates Neuronal Apoptosis by Zuko, Amila, Oguro-Ando, Asami, Post, Harm, Taggenbrock, Renske L R E, van Dijk, Roland E, Altelaar, A F Maarten, Heck, Albert J R, Petrenko, Alexander G, van der Zwaag, Bert, Shimoda, Yasushi, Pasterkamp, R J, Burbach, J P H

“…In view of important neurobiological functions of the cell adhesion molecule contactin-6 (Cntn6) that have emerged from studies on null-mutant mice and autism…”
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The Interaction Between Contactin and Amyloid Precursor Protein and Its Role in Alzheimer’s Disease by Bamford, Rosemary A., Widagdo, Jocelyn, Takamura, Natsuki, Eve, Madeline, Anggono, Victor, Oguro-Ando, Asami

“…•Genome-wide association study shows link between Contactin family and dementia.•Dysregulated expression of Contactin in the post-mortem brain tissue of AD…”
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A current view on contactin-4, -5, and -6: Implications in neurodevelopmental disorders by Oguro-Ando, Asami, Zuko, Amila, Kleijer, Kristel T.E., Burbach, J. Peter H.

“…Contactins (Cntns) are a six-member subgroup of the immunoglobulin cell adhesion molecule superfamily (IgCAMs) with pronounced brain expression and function…”
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Regulation of astrocyte metabolism by mitochondrial translocator protein 18kDa by Firth, Wyn, Robb, Josephine L, Stewart, Daisy, Pye, Katherine R, Bamford, Rosemary, Asami Oguro‐Ando, Beall, Craig, Ellacott, Kate L J

“…The mitochondrial translocator protein 18 kDa (TSPO) has been linked to functions from steroidogenesis to regulation of cellular metabolism and is an…”
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Study of the Functions and Activities of Neuronal K-Cl Co-Transporter KCC2 Using Western Blotting by Josiah, Sunday Solomon, Meor Azlan, Nur Farah, Oguro-Ando, Asami, Zhang, Jinwei

“…Potassium chloride cotransporters 2 (KCC2) is a member of the solute carrier family 12 (SLC12) of cation-chloride-cotransporters (CCCs), found exclusively in…”
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Unraveling the CLCC1 interactome: Impact of the Asp25Glu variant and its interaction with SigmaR1 at the Mitochondrial-Associated ER Membrane (MAM) by D'Atri, Ilaria, Martin, Emily-Rose, Yang, Liming, Sears, Elizabeth, Baple, Emma, Crosby, Andrew H., Chilton, John K., Oguro-Ando, Asami

“…•Enhanced immunoprecipitation and LC-MS analysis confirm CLCC1’s primary interactions with proteins localized to the ER and nuclear outer membrane, affirming…”
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Genetically proxied therapeutic prolyl-hydroxylase inhibition and cardiovascular risk by Harlow, Charli E, Patel, Vickas V, Waterworth, Dawn M, Wood, Andrew R, Beaumont, Robin N, Ruth, Katherine S, Tyrrell, Jessica, Oguro-Ando, Asami, Chu, Audrey Y, Frayling, Timothy M

“…Prolyl hydroxylase (PHD) inhibitors are in clinical development for anaemia in chronic kidney disease. Epidemiological studies have reported conflicting…”
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F13FUNCTIONAL ANALYSIS OF THE SCHIZOPHRENIA ASSOCIATED GENE AS3MT IN SH-SY5Y NEUROBLASTOMA CELLS by Washer, Sam, Oguro-Ando, Asami, Burrage, Joe, Mill, Jonathan, Jeffries, Aaron, Dempster, Emma

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Contactins in the neurobiology of autism by Zuko, Amila, Kleijer, Kristel T.E., Oguro-Ando, Asami, Kas, Martien J.H., van Daalen, Emma, van der Zwaag, Bert, Burbach, J. Peter H.

“…Autism is a disease of brain plasticity. Inspiring work of Willem Hendrik Gispen on neuronal plasticity has stimulated us to investigate gene defects in autism…”
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Identification and single-base gene-editing functional validation of a cis-EPO variant as a genetic predictor for EPO-increasing therapies by Harlow, Charli E., Gandawijaya, Josan, Bamford, Rosemary A., Martin, Emily-Rose, Wood, Andrew R., van der Most, Peter J., Tanaka, Toshiko, Leonard, Hampton L., Etheridge, Amy S., Innocenti, Federico, Beaumont, Robin N., Tyrrell, Jessica, Nalls, Mike A., Simonsick, Eleanor M., Garimella, Pranav S., Shiroma, Eric J., Verweij, Niek, van der Meer, Peter, Gansevoort, Ron T., Snieder, Harold, Gallins, Paul J., Jima, Dereje D., Wright, Fred, Zhou, Yi-hui, Ferrucci, Luigi, Bandinelli, Stefania, Hernandez, Dena G., van der Harst, Pim, Patel, Vickas V., Waterworth, Dawn M., Chu, Audrey Y., Oguro-Ando, Asami, Frayling, Timothy M.

“…Hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs) are currently under clinical development for treating anemia in chronic kidney disease (CKD),…”
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