Search Results - "Ogura, Satomi"
-
1
In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancers
Published in Nature communications (24-04-2019)“…Stabilisation of fragile oligonucleotides, typically small interfering RNA (siRNA), is one of the most critical issues for oligonucleotide therapeutics. Many…”
Get full text
Journal Article -
2
Fine-Tuning of Hydrophobicity in Amphiphilic Polyaspartamide Derivatives for Rapid and Transient Expression of Messenger RNA Directed Toward Genome Engineering in Brain
Published in ACS central science (27-11-2019)“…Rapid and transient expression of in vitro transcribed mRNA (IVT mRNA) in target cells is a current major challenge in genome engineering therapy. To improve…”
Get full text
Journal Article -
3
Antiferromagnetic Ordering in the Single-Component Molecular Conductor [Pd(tmdt)2]
Published in Inorganic chemistry (01-08-2016)“…Crystals of [Pd(tmdt)2] (tmdt = trimethylenetetrathiafulvalenedithiolate) were prepared in order to investigate their physical properties. The electrical…”
Get full text
Journal Article -
4
Single-component Magnetic Molecular Conductor [Fe(dmdt)2] (dmdt: dimethyltetrathiafulvalenedithiolate)
Published in Chemistry letters (05-09-2013)“…Molecular metal complexes with interactions between localized spins and conduction electrons are expected to show interesting electronic and magnetic…”
Get full text
Journal Article -
5
A 50‐nm‐Sized Micellar Assembly of Thermoresponsive Polymer‐Antisense Oligonucleotide Conjugates for Enhanced Gene Knockdown in Lung Cancer by Intratracheal Administration
Published in Advanced therapeutics (01-02-2020)“…For intratracheal delivery of antisense oligonucleotides (ASOs) to lung cancer, a nano‐sized micellar assembly is fabricated from an ASO conjugate with…”
Get full text
Journal Article -
6
Systemic Brain Delivery of Antisense Oligonucleotides across the Blood–Brain Barrier with a Glucose‐Coated Polymeric Nanocarrier
Published in Angewandte Chemie International Edition (18-05-2020)“…Current antisense oligonucleotide (ASO) therapies for the treatment of central nervous system (CNS) disorders are performed through invasive administration,…”
Get full text
Journal Article -
7
Fine-tuning of polyaspartamide derivatives with alicyclic moieties for systemic mRNA delivery
Published in Journal of controlled release (01-02-2022)“…Development of efficient delivery vehicles for in vitro transcribed mRNA (IVT mRNA) is currently a major challenge in nanomedicines. For systemic mRNA…”
Get full text
Journal Article -
8
Size-Dependent Glioblastoma Targeting by Polymeric Nanoruler with Prolonged Blood Circulation
Published in Bioconjugate chemistry (21-08-2024)“…Currently, there is no effective treatment for glioblastoma multiforme (GBM), the most frequent and malignant type of brain tumor. The blood–brain (tumor)…”
Get full text
Journal Article -
9
Hydrophobicity Tuning of Cationic Polyaspartamide Derivatives for Enhanced Antisense Oligonucleotide Delivery
Published in Bioconjugate chemistry (21-02-2024)“…Various cationic polymers are used to deliver polyplex-mediated antisense oligonucleotides (ASOs). However, few studies have investigated the structural…”
Get full text
Journal Article -
10
Size-tunable PEG-grafted copolymers as a polymeric nanoruler for passive targeting muscle tissues
Published in Journal of controlled release (01-07-2022)“…Muscle-targeted drug delivery is a major challenge in nanomedicine. The extravasation of nanomedicines (or nanoparticles) from the bloodstream into muscle…”
Get full text
Journal Article -
11
A Single-component Molecular Conductor with Metal–Metal Bonding, [Pd(hfdt)2] (hfdt: bis(trifluoromethyl)tetrathiafulvalenedithiolate)
Published in Chemistry letters (05-03-2016)“…A new single-component palladium complex, [Pd(hfdt)2] (hfdt: bis(trifluoromethyl)tetrathiafulvalenedithiolate), was prepared. Single-crystal structure analysis…”
Get full text
Journal Article -
12
-
13
A Single-component Molecular Conductor with Metal-Metal Bonding, [Pd(hfdt)2] (hfdt
Published in Chemistry letters (01-03-2016)“…A new single-component palladium complex, [Pd(hfdt)2] (hfdt: bis(trifluoromethyl)tetrathiafulvalenedithiolate), was prepared. Single-crystal structure analysis…”
Get full text
Journal Article -
14
Antisense Oligonucleotides: A 50‐nm‐Sized Micellar Assembly of Thermoresponsive Polymer‐Antisense Oligonucleotide Conjugates for Enhanced Gene Knockdown in Lung Cancer by Intratracheal Administration (Adv. Therap. 2/2020)
Published in Advanced therapeutics (01-02-2020)“…In article number 1900123, Kanjiro Miyata and co‐workers develop a micellar assembly (ASOball) from a covalent conjugation between a thermoresponsive polymer,…”
Get full text
Journal Article -
15
Single-component Magnetic Molecular Conductor [Fe(dmdt)2] (dmdt
Published in Chemistry letters (01-09-2013)“…Molecular metal complexes with interactions between localized spins and conduction electrons are expected to show interesting electronic and magnetic…”
Get full text
Journal Article -
16
Systemic Brain Delivery of Antisense Oligonucleotides across the Blood–Brain Barrier with a Glucose‐Coated Polymeric Nanocarrier
Published in Angewandte Chemie (18-05-2020)“…Current antisense oligonucleotide (ASO) therapies for the treatment of central nervous system (CNS) disorders are performed through invasive administration,…”
Get full text
Journal Article -
17
Influence of Elbow Joint Position on Shoulder Joint External Rotation Movement: An Ultra-sound Sonography Study
Published in Rigaku ryoho kagaku (2013)“…[Purpose] The purpose of this study was to examine the influence of different elbow joint positions on shoulder joint external rotation movement using reach…”
Get full text
Journal Article -
18