Search Results - "Ogura, Atsuo"

Recent advancements in cloning by somatic cell nuclear transfer by Ogura, Atsuo, Inoue, Kimiko, Wakayama, Teruhiko

“…Somatic cell nuclear transfer (SCNT) cloning is the sole reproductive engineering technology that endows the somatic cell genome with totipotency. Since the…”
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A New, Dynamic Era for Somatic Cell Nuclear Transfer? by Loi, Pasqualino, Iuso, Domenico, Czernik, Marta, Ogura, Atsuo

“…Cloning animals by somatic cell nuclear transfer (SCNT) has remained an uncontrollable process for many years. High rates of embryonic losses, stillbirths, and…”
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Reprogramming of the histone H3.3 landscape in the early mouse embryo by Ishiuchi, Takashi, Abe, Shusaku, Inoue, Kimiko, Yeung, Wan Kin Au, Miki, Yuka, Ogura, Atsuo, Sasaki, Hiroyuki

“…Epigenetic reprogramming of the zygote involves dynamic incorporation of histone variant H3.3. However, the genome-wide distribution and dynamics of H3.3…”
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In memory of Dr. Ryuzo Yanagimachi (Yana) (1928–2023) by WAKAYAMA, Teruhiko, OGURA, Atsuo

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Formation of spermatogonia and fertile oocytes in golden hamsters requires piRNAs by Loubalova, Zuzana, Fulka, Helena, Horvat, Filip, Pasulka, Josef, Malik, Radek, Hirose, Michiko, Ogura, Atsuo, Svoboda, Petr

“…PIWI-interacting RNAs (piRNAs) support the germline by suppressing retrotransposons. Studies of the pathway in mice have strongly shaped the view that…”
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Loss of H3K27me3 imprinting in the Sfmbt2 miRNA cluster causes enlargement of cloned mouse placentas by Inoue, Kimiko, Ogonuki, Narumi, Kamimura, Satoshi, Inoue, Hiroki, Matoba, Shogo, Hirose, Michiko, Honda, Arata, Miura, Kento, Hada, Masashi, Hasegawa, Ayumi, Watanabe, Naomi, Dodo, Yukiko, Mochida, Keiji, Ogura, Atsuo

“…Somatic cell nuclear transfer (SCNT) in mammals is an inefficient process that is frequently associated with abnormal phenotypes, especially in placentas…”
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ROS Are Required for Mouse Spermatogonial Stem Cell Self-Renewal by Morimoto, Hiroko, Iwata, Kazumi, Ogonuki, Narumi, Inoue, Kimiko, Atsuo, Ogura, Kanatsu-Shinohara, Mito, Morimoto, Takeshi, Yabe-Nishimura, Chihiro, Shinohara, Takashi

“…Reactive oxygen species (ROS) generation is implicated in stem cell self-renewal in several tissues but is thought to be detrimental for spermatogenesis as…”
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Colorimetric detection of loop-mediated isothermal amplification reaction by using hydroxy naphthol blue by Goto, Motoki, Honda, Eiichi, Ogura, Atsuo, Nomoto, Akio, Hanaki, Ken-Ichi

“…Loop-mediated isothermal amplification (LAMP), a novel gene amplification method, enables the synthesis of larger amounts of both DNA and a visible…”
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In vitro production of functional sperm in cultured neonatal mouse testes by Sato, Takuya, Katagiri, Kumiko, Gohbara, Ayako, Inoue, Kimiko, Ogonuki, Narumi, Ogura, Atsuo, Kubota, Yoshinobu, Ogawa, Takehiko

“…Preserving sperm fertility Reproducing the complex process of spermatogenesis in vitro might lead to the development of new diagnostic and therapeutic…”
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Cloning Mice by Ogura, Atsuo

“…Viable and fertile mice can be generated by somatic nuclear transfer into enucleated oocytes, presumably because the transplanted somatic cell genome becomes…”
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Editing the Genome of the Golden Hamster (Mesocricetus auratus) by Hirose, Michiko, Tomishima, Toshiko, Ogura, Atsuo

“…The golden (Syrian) hamster (Mesocricetus auratus) is a small rodent belonging to the Cricetidae family. Golden hamsters have several unique characteristics…”
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Loss of H3K27me3 Imprinting in Somatic Cell Nuclear Transfer Embryos Disrupts Post-Implantation Development by Matoba, Shogo, Wang, Huihan, Jiang, Lan, Lu, Falong, Iwabuchi, Kumiko A., Wu, Xiaoji, Inoue, Kimiko, Yang, Lin, Press, William, Lee, Jeannie T., Ogura, Atsuo, Shen, Li, Zhang, Yi

“…Animal cloning can be achieved through somatic cell nuclear transfer (SCNT), although the live birth rate is relatively low. Recent studies have identified…”
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Role of CD4 + T Cells in Allergic Airway Diseases: Learning from Murine Models by Miura, Kento, Inoue, Kimiko, Ogura, Atsuo, Kaminuma, Osamu

“…The essential contribution of CD4 T cells in allergic airway diseases has been demonstrated, especially by using various murine models of antigen-induced…”
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CRISPR/Cas9-based genetic screen of SCNT-reprogramming resistant genes identifies critical genes for male germ cell development in mice by Akter, Most Sumona, Hada, Masashi, Shikata, Daiki, Watanabe, Gen, Ogura, Atsuo, Matoba, Shogo

“…Male germ cells undergo complex developmental processes eventually producing spermatozoa through spermatogenesis, although the molecular mechanisms remain…”
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PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos by Nakamura, Toshinobu, Liu, Yu-Jung, Nakashima, Hiroyuki, Umehara, Hiroki, Inoue, Kimiko, Matoba, Shogo, Tachibana, Makoto, Ogura, Atsuo, Shinkai, Yoichi, Nakano, Toru

“…The binding of PGC7 to maternal chromatin, which is important for methylation maintenance during embryogenesis, is shown to be dependent on a particular…”
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Acrosin is essential for sperm penetration through the zona pellucida in hamsters by Hirose, Michiko, Honda, Arata, Fulka, Helena, Tamura-Nakano, Miwa, Matoba, Shogo, Tomishima, Toshiko, Mochida, Keiji, Hasegawa, Ayumi, Nagashima, Kiyoshi, Inoue, Kimiko, Ohtsuka, Masato, Baba, Tadashi, Yanagimachi, Ryuzo, Ogura, Atsuo

“…During natural fertilization, mammalian spermatozoa must pass through the zona pellucida before reaching the plasma membrane of the oocyte. It is assumed that…”
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A non-mosaic transchromosomic mouse model of down syndrome carrying the long arm of human chromosome 21 by Kazuki, Yasuhiro, Gao, Feng J, Li, Yicong, Moyer, Anna J, Devenney, Benjamin, Hiramatsu, Kei, Miyagawa-Tomita, Sachiko, Abe, Satoshi, Kazuki, Kanako, Kajitani, Naoyo, Uno, Narumi, Takehara, Shoko, Takiguchi, Masato, Yamakawa, Miho, Hasegawa, Atsushi, Shimizu, Ritsuko, Matsukura, Satoko, Noda, Naohiro, Ogonuki, Narumi, Inoue, Kimiko, Matoba, Shogo, Ogura, Atsuo, Florea, Liliana D, Savonenko, Alena, Xiao, Meifang, Wu, Dan, Batista, Denise As, Yang, Junhua, Qiu, Zhaozhu, Singh, Nandini, Richtsmeier, Joan T, Takeuchi, Takashi, Oshimura, Mitsuo, Reeves, Roger H

“…Animal models of Down syndrome (DS), trisomic for human chromosome 21 (HSA21) genes or orthologs, provide insights into better understanding and treatment…”
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Use of anti-inhibin monoclonal antibody for increasing the litter size of mouse strains and its application to in vivo-genome editing technology by Hasegawa, Ayumi, Mochida, Keiji, Nakamura, Ayaka, Miyagasako, Rico, Ohtsuka, Masato, Hatakeyama, Masahiko, Ogura, Atsuo

“…The litter size of mouse strains is determined by the number of oocytes naturally ovulated. Many attempts have been made to increase litter sizes by…”
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Noncanonical imprinting sustains embryonic development and restrains placental overgrowth by Matoba, Shogo, Kozuka, Chisayo, Miura, Kento, Inoue, Kimiko, Kumon, Mami, Hayashi, Ryoya, Ohhata, Tatsuya, Ogura, Atsuo, Inoue, Azusa

“…Genomic imprinting regulates parental origin-dependent monoallelic gene expression. It is mediated by either germline differential methylation of DNA…”
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In vitro production of fertile sperm from murine spermatogonial stem cell lines by Sato, Takuya, Katagiri, Kumiko, Yokonishi, Tetsuhiro, Kubota, Yoshinobu, Inoue, Kimiko, Ogonuki, Narumi, Matoba, Shogo, Ogura, Atsuo, Ogawa, Takehiko

“…Spermatogonial stem cells (SSCs) are the only stem cells in the body that transmit genetic information to the next generation. The long-term propagation of…”
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