Search Results - "Ogunrombi, Modupe O."
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Leading Paediatric Infectious Diseases-Current Trends, Gaps, and Future Prospects in Oral Pharmacotherapeutic Interventions
Published in Pharmaceutics (26-05-2024)“…Paediatric infectious diseases contribute significantly to global health challenges. Conventional therapeutic interventions are not always suitable for…”
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A Micro-Configured Multiparticulate Reconstitutable Suspension Powder of Fixed Dose Rifampicin and Pyrazinamide: Optimal Fabrication and In Vitro Quality Evaluation
Published in Pharmaceutics (25-12-2022)“…The scarcity of age-appropriate pharmaceutical formulations is one of the major challenges impeding successful management of tuberculosis (TB) prevalence in…”
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Pediatric Tuberculosis Management: A Global Challenge or Breakthrough?
Published in Children (Basel) (27-07-2022)“…Managing pediatric tuberculosis (TB) remains a public health problem requiring urgent and long-lasting solutions as TB is one of the top ten causes of ill…”
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Inhibition of monoamine oxidase B by selected benzimidazole and caffeine analogues
Published in Bioorganic & medicinal chemistry (01-06-2007)“…We have recently reported that a series of ( E)-8-styrylcaffeines and ( E)-2-styrylbenzimidazoles are moderate to very potent competitive inhibitors of…”
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Structure–activity relationships in the inhibition of monoamine oxidase B by 1-methyl-3-phenylpyrroles
Published in Bioorganic & medicinal chemistry (01-03-2008)“…1-Methyl-3-phenyl-3-pyrrolines are structural analogues of the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and like MPTP are selective…”
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Interactions of 1-methyl-3-phenylpyrrolidine and 3-methyl-1-phenyl-3-azabicyclo[3.1.0]hexane with monoamine oxidase B
Published in Bioorganic & medicinal chemistry (01-06-2010)“…The parkinsonian inducing agent 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and its corresponding five-membered ring analogue…”
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Deuterium isotope effects for the oxidation of 1-methyl-3-phenyl-3-pyrrolinyl analogues by monoamine oxidase B
Published in Bioorganic & medicinal chemistry (01-10-2008)“…The parkinsonian inducing agent, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), is a cyclic tertiary allylamine exhibiting good monoamine oxidase B…”
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Neurotoxicity studies with the monoamine oxidase B substrate 1-methyl-3-phenyl-3-pyrroline
Published in Life sciences (1973) (19-07-2007)“…The neurotoxic properties of the parkinsonian inducing agent 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) are dependent on its metabolic activation in a…”
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Impact of artificial intelligence and digital technology-based diagnostic tools for communicable and non-communicable diseases in Africa
Published in African journal of laboratory medicine (21-11-2024)“…Background: Artificial intelligence (AI) and digital technology, as advanced human-created tools, are influencing the healthcare sector.Aim: This review…”
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Overview of Medical and Biological Applications of Indium(III) Complexes
Published in Chemistry Africa (01-05-2024)“…Indium(III) complexes are versatile species that emit Auger electrons which made them a choice for a wide range of biological and medical applications. The…”
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