Search Results - "Ogunkoya, Ayodele O."

Chemical Protein Synthesis by Chemoselective α-Ketoacid-Hydroxylamine (KAHA) Ligations with 5-Oxaproline by Pattabiraman, Vijaya R., Ogunkoya, Ayodele O., Bode, Jeffrey W.

“…The chemical synthesis of proteins from unprotected peptide segments uses KAHA ligation with 5‐oxaproline, which is incorporated readily into peptides by…”
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Tandem-Cleavage Linkers Improve the In Vivo Stability and Tolerability of Antibody–Drug Conjugates by Chuprakov, Stepan, Ogunkoya, Ayodele O, Barfield, Robyn M, Bauzon, Maxine, Hickle, Colin, Kim, Yun Cheol, Yeo, Dominick, Zhang, Fangjiu, Rabuka, David, Drake, Penelope M

“…Although peptide motifs represent the majority of cleavable linkers used in clinical-stage antibody–drug conjugates (ADCs), the sequences are often sensitive…”
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Sequential α-Ketoacid-Hydroxylamine (KAHA) Ligations: Synthesis of C-Terminal Variants of the Modifier Protein UFM1 by Ogunkoya, Ayodele O., Pattabiraman, Vijaya R., Bode, Jeffrey W.

“…3 for 3: Sequential α‐ketoacid–hydroxylamine (KAHA) ligations with 5‐oxaproline allow access to the modifier protein UFM1 (Ubiquitin‐fold modifier 1) with a…”
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Aspartic Acid Forming α‑Ketoacid–Hydroxylamine (KAHA) Ligations with (S)‑4,4-Difluoro-5-oxaproline by Baldauf, Simon, Ogunkoya, Ayodele O, Boross, Gábor N, Bode, Jeffrey W

“…The α-ketoacid-hydroxylamine (KAHA) ligation allows the coupling of unprotected peptide segments. Currently, the most applied hydroxylamine is the 5-membered…”
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Sequential [alpha]-Ketoacid-Hydroxylamine (KAHA) Ligations: Synthesis of C-Terminal Variants of the Modifier Protein UFM1 by Ogunkoya, Ayodele O, Pattabiraman, Vijaya R, Bode, Jeffrey W

“…3 for 3: Sequential [alpha]-ketoacid-hydroxylamine (KAHA) ligations with 5-oxaproline allow access to the modifier protein UFM1 (Ubiquitin-fold modifier 1)…”
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A Novel HER2-targeted Antibody–drug Conjugate Offers the Possibility of Clinical Dosing at Trastuzumab-equivalent Exposure Levels by Barfield, Robyn M., Kim, Yun Cheol, Chuprakov, Stepan, Zhang, Fangjiu, Bauzon, Maxine, Ogunkoya, Ayodele O., Yeo, Dominick, Hickle, Colin, Pegram, Mark D., Rabuka, David, Drake, Penelope M.

“…Abstract Trastuzumab and the related ADC, ado-trastuzumab emtansine (T-DM1), both target HER2-overexpressing cells. Together, these drugs have treatment…”
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Corrigendum: Chemical Protein Synthesis by Chemoselective [alpha]-Ketoacid-Hydroxylamine (KAHA) Ligations with 5-Oxaproline by Pattabiraman, Vijaya R, Ogunkoya, Ayodele O, Bode, Jeffrey W

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Corrigendum: Sequential α-Ketoacid-Hydroxylamine (KAHA) Ligations: Synthesis of C-Terminal Variants of the Modifier Protein UFM1 by Ogunkoya, Ayodele O., Pattabiraman, Vijaya R., Bode, Jeffrey W.

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Corrigendum: Chemical Protein Synthesis by Chemoselective α-Ketoacid-Hydroxylamine (KAHA) Ligations with 5-Oxaproline by Pattabiraman, Vijaya R., Ogunkoya, Ayodele O., Bode, Jeffrey W.

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Corrigendum: Sequential [alpha]-Ketoacid-Hydroxylamine (KAHA) Ligations: Synthesis of C-Terminal Variants of the Modifier Protein UFM1 by Ogunkoya, Ayodele O, Pattabiraman, Vijaya R, Bode, Jeffrey W

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Chemical Protein Synthesis by Chemoselective [alpha]-Ketoacid-Hydroxylamine (KAHA) Ligations with 5-Oxaproline by Pattabiraman, Vijaya R, Ogunkoya, Ayodele O, Bode, Jeffrey W

“…The chemical synthesis of proteins from unprotected peptide segments uses KAHA ligation with 5-oxaproline, which is incorporated readily into peptides by…”
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Cover Picture: Chemical Protein Synthesis by Chemoselective [alpha]-Ketoacid-Hydroxylamine (KAHA) Ligations with 5-Oxaproline (Angew. Chem. Int. Ed. 21/2012) by Pattabiraman, Vijaya R, Ogunkoya, Ayodele O, Bode, Jeffrey W

“…The chemical synthesis of proteins from unprotected peptide segments uses KAHA ligation with 5-oxaproline, which is incorporated readily into peptides by…”
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Cover Picture: Chemical Protein Synthesis by Chemoselective α-Ketoacid-Hydroxylamine (KAHA) Ligations with 5-Oxaproline (Angew. Chem. Int. Ed. 21/2012) by Pattabiraman, Vijaya R., Ogunkoya, Ayodele O., Bode, Jeffrey W.

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Berichtigung: Sequentielle α‐Ketosäurehydroxylamin(KAHA)‐Ligationen: Synthese C‐terminaler Varianten des Modifikationsproteins UFM1 by Ogunkoya, Ayodele O., Pattabiraman, Vijaya R., Bode, Jeffrey W.

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Berichtigung: Chemical Protein Synthesis by Chemoselective [alpha]-Ketoacid-Hydroxylamine (KAHA) Ligations with 5-Oxaproline by Pattabiraman, Vijaya R, Ogunkoya, Ayodele O, Bode, Jeffrey W

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Berichtigung: Chemical Protein Synthesis by Chemoselective α-Ketoacid-Hydroxylamine (KAHA) Ligations with 5-Oxaproline by Pattabiraman, Vijaya R., Ogunkoya, Ayodele O., Bode, Jeffrey W.

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Sequentielle α‐Ketosäurehydroxylamin(KAHA)‐Ligationen: Synthese C‐terminaler Varianten des Modifikationsproteins UFM1 by Ogunkoya, Ayodele O., Pattabiraman, Vijaya R., Bode, Jeffrey W.

“…3 für 3: Die sequentielle α‐Ketosäurehydroxylamin(KAHA)‐Ligation mit 5‐Oxaprolin eröffnet den einfachen Zugang zu C‐terminalen Amiden, Carbonsäuren und…”
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Chemical Protein Synthesis by Chemoselective α-Ketoacid-Hydroxylamine (KAHA) Ligations with 5-Oxaproline by Pattabiraman, Vijaya R., Ogunkoya, Ayodele O., Bode, Jeffrey W.

“…Die chemische Synthese von Proteinen ausgehend von ungeschützten Peptidsegmenten nutzt die KAHA‐Ligation mit 5‐Oxaprolin, das problemlos bei der…”
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Titelbild: Chemical Protein Synthesis by Chemoselective [alpha]-Ketoacid-Hydroxylamine (KAHA) Ligations with 5-Oxaproline (Angew. Chem. 21/2012) by Pattabiraman, Vijaya R, Ogunkoya, Ayodele O, Bode, Jeffrey W

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Titelbild: Chemical Protein Synthesis by Chemoselective α-Ketoacid-Hydroxylamine (KAHA) Ligations with 5-Oxaproline (Angew. Chem. 21/2012) by Pattabiraman, Vijaya R., Ogunkoya, Ayodele O., Bode, Jeffrey W.

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