Plasmacytoma of the hard palate

Multiple myeloma is a systemic malignant disease and is associated with a poor prognosis. It is characterized by neoplastic proliferation of plasma cells involved in the production and secretion of monoclonal immunoglobulins (M proteins). It is generally a disseminated disease involving many bones....

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Bibliographic Details
Published in:	The Journal of craniofacial surgery Vol. 16; no. 1; pp. 164 - 169
Main Authors:	Ozdemir, Ragip, Kayiran, Oguz, Oruc, Melike, Karaaslan, Onder, Koçer, Ugur, Ogun, Dincer
Format:	Journal Article
Language:	English
Published:	United States 01-01-2005
Subjects:	Dentistry Diagnosis, Differential Female Humans Middle Aged Multiple Myeloma - diagnosis Palatal Neoplasms - pathology Palate, Hard - pathology Plasmacytoma - pathology
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Summary:	Multiple myeloma is a systemic malignant disease and is associated with a poor prognosis. It is characterized by neoplastic proliferation of plasma cells involved in the production and secretion of monoclonal immunoglobulins (M proteins). It is generally a disseminated disease involving many bones. Systemic symptoms include bone pain, pathologic fracture, renal failure, hypercalcemia, weight loss, anemia, thrombocytopenia, and neutropenia. This condition may occur as a solitary lesion (solitary plasmacytoma), which in some patients eventually progresses to plasma cell myeloma. Extramedullary plasmacytoma is defined as neoplastic proliferation of plasma cells in the soft tissue. It usually occurs in the upper respiratory tract, such as the nasal cavity or posterior oropharynx. The authors present a rare plasmacytoma case with maxilla involvement.
Bibliography:	ObjectType-Case Study-3 SourceType-Scholarly Journals-1 content type line 23 ObjectType-Review-1 ObjectType-Feature-5 ObjectType-Report-2 ObjectType-Article-4
ISSN:	1049-2275
DOI:	10.1097/00001665-200501000-00034