Search Results - "Ogmundsdottir, H"

Restricted leucine zipper dimerization and specificity of DNA recognition of the melanocyte master regulator MITF by Pogenberg, Vivian, Ogmundsdóttir, Margrét H, Bergsteinsdóttir, Kristín, Schepsky, Alexander, Phung, Bengt, Deineko, Viktor, Milewski, Morlin, Steingrímsson, Eiríkur, Wilmanns, Matthias

“…Microphthalmia-associated transcription factor (MITF) is a master regulator of melanocyte development and an important oncogene in melanoma. MITF heterodimeric…”
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Proton-pump inhibitors among adults: a nationwide drug-utilization study by Hálfdánarson, Óskar Ö., Pottegård, Anton, Björnsson, Einar S., Lund, Sigrún H., Ogmundsdottir, Margret H., Steingrímsson, Eiríkur, Ogmundsdottir, Helga M., Zoega, Helga

“…Background: The use of proton-pump inhibitors (PPIs) has grown worldwide, and there are concerns about increased unsubstantiated long-term use. The aim of the…”
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A short isoform of ATG7 fails to lipidate LC3/GABARAP by Ogmundsdottir, M. H., Fock, V., Sooman, L., Pogenberg, V., Dilshat, R., Bindesbøll, C., Ogmundsdottir, H. M., Simonsen, A., Wilmanns, M., Steingrimsson, E.

“…Autophagy is a degradation pathway important for cellular homeostasis. The E1-like enzyme ATG7 is a key component of the autophagy machinery, with the main…”
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MITF has a central role in regulating starvation-induced autophagy in melanoma by Möller, Katrin, Sigurbjornsdottir, Sara, Arnthorsson, Asgeir O., Pogenberg, Vivian, Dilshat, Ramile, Fock, Valerie, Brynjolfsdottir, Solveig H., Bindesboll, Christian, Bessadottir, Margret, Ogmundsdottir, Helga M., Simonsen, Anne, Larue, Lionel, Wilmanns, Matthias, Thorsson, Vesteinn, Steingrimsson, Eirikur, Ogmundsdottir, Margret H.

“…The MITF transcription factor is a master regulator of melanocyte development and a critical factor in melanomagenesis. The related transcription factors TFEB…”
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A Polymorphism in IRF4 Affects Human Pigmentation through a Tyrosinase-Dependent MITF/TFAP2A Pathway by Praetorius, Christian, Grill, Christine, Stacey, Simon N., Metcalf, Alexander M., Gorkin, David U., Robinson, Kathleen C., Van Otterloo, Eric, Kim, Reuben S.Q., Bergsteinsdottir, Kristin, Ogmundsdottir, Margret H., Magnusdottir, Erna, Mishra, Pravin J., Davis, Sean R., Guo, Theresa, Zaidi, M. Raza, Helgason, Agnar S., Sigurdsson, Martin I., Meltzer, Paul S., Merlino, Glenn, Petit, Valerie, Larue, Lionel, Loftus, Stacie K., Adams, David R., Sobhiafshar, Ulduz, Emre, N.C. Tolga, Pavan, William J., Cornell, Robert, Smith, Aaron G., McCallion, Andrew S., Fisher, David E., Stefansson, Kari, Sturm, Richard A., Steingrimsson, Eirikur

“…Sequence polymorphisms linked to human diseases and phenotypes in genome-wide association studies often affect noncoding regions. A SNP within an intron of the…”
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Proton pump inhibitor use and risk of breast cancer, prostate cancer, and malignant melanoma: An Icelandic population‐based case‐control study by Hálfdánarson, Óskar Ö., Fall, Katja, Ogmundsdottir, Margret H., Lund, Sigrún H., Steingrímsson, Eiríkur, Ogmundsdottir, Helga M., Zoega, Helga

“…Purpose Increased expression of Vacuolar‐type H+ ATPases (V‐ATPases), in the plasma membrane of cancer cells has been suggested to contribute to the…”
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Publisher Correction: A short isoform of ATG7 fails to lipidate LC3/GABARAP by Ogmundsdottir, M. H., Fock, V., Sooman, L., Pogenberg, V., Dilshat, R., Bindesbøll, C., Ogmundsdottir, H. M., Simonsen, A., Wilmanns, M., Steingrimsson, E.

“…A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper…”
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Germline variants of ATG7 in familial cholangiocarcinoma alter autophagy and p62 by Greer, Stephanie U., Chen, Jiamin, Ogmundsdottir, Margret H., Ayala, Carlos, Lau, Billy T., Delacruz, Richard Glenn C., Sandoval, Imelda T., Kristjansdottir, Sigrun, Jones, David A., Haslem, Derrick S., Romero, Robin, Fulde, Gail, Bell, John M., Jonasson, Jon G., Steingrimsson, Eirikur, Ji, Hanlee P., Nadauld, Lincoln D.

“…Autophagy is a housekeeping mechanism tasked with eliminating misfolded proteins and damaged organelles to maintain cellular homeostasis. Autophagy deficiency…”
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Lichen compound protolichesterinic acid inhibits DNA synthesis and DNA repair in cultured cancer cells by Ogmundsdottir, H, Hauksdottir, H, Thorsteinsdottir, J

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Role of TP53 in the progression of pre-malignant and malignant oral mucosal lesions. A follow-up study of 144 patients by Ögmundsdóttir, H. M., Björnsson, J., Holbrook, W. P.

“…Background:  Prediction of progression from pre‐malignant oral mucosal lesions to malignancy, or recurrence of an existing oral squamous cell carcinoma (OSCC),…”
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Anti-proliferative lichen compounds with inhibitory activity on 12(S)-HETE production in human platelets by Bucar, F., Schneider, I., Ögmundsdóttir, H., Ingólfsdóttir, K.

“…Several lichen compounds, i.e. lobaric acid (1), a β-orcinol depsidone from Stereocaulon alpinum L., (+)-protolichesterinic acid (2), an aliphatic…”
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PINK1 regulated mitophagy is evident in skeletal muscles by Singh, Francois, Wilhelm, Lea, Prescott, Alan R, Ostacolo, Kevin, Zhao, Jin-Feng, Ogmundsdottir, Margret H, Ganley, Ian G

“…PINK1, mutated in familial forms of Parkinson's disease, initiates mitophagy following mitochondrial depolarization. However, it is difficult to monitor this…”
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The influence of partial or total thymectomy during open heart surgery in infants on the immune function later in life by EYSTEINSDOTTIR, J. H., FREYSDOTTIR, J., HARALDSSON, A., STEFANSDOTTIR, J., SKAFTADOTTIR, I., HELGASON, H., OGMUNDSDOTTIR, H. M.

“…SUMMARY Infants undergoing open heart surgery often have all or part of their thymus removed. The activity of the immune system has not been investigated…”
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Proton-shuttling lichen compound usnic acid affects mitochondrial and lysosomal function in cancer cells by Bessadottir, Margret, Egilsson, Mar, Einarsdottir, Eydis, Magnusdottir, Iris H, Ogmundsdottir, Margret H, Omarsdottir, Sesselja, Ogmundsdottir, Helga M

“…The lichen compound usnic acid (UA) is a lipophilic weak acid that acts as a proton shuttle and causes loss of mitochondrial inner membrane potential. In the…”
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Improving smoking cessation after myocardial infarction by systematically implementing evidence-based treatment methods: a prospective observational cohort study by Leosdottir, M, Warjerstam, S, Ogmundsdottir Michelsen, H, Schlyter, M, Hag, E, Wallert, J, Larsson, M

“…Abstract Background For smokers who suffer a myocardial infarction (MI), smoking cessation is the most effective measure to reduce recurrent event risk. Still,…”
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Effect of a lifestyle-focused electronic patient support application on risk factor management in post-myocardial infarction patients – a randomized controlled trial by Ogmundsdottir Michelsen, H, Sjolin, I, Back, M, Gonzalez, M, Olsson, A, Sandberg, C, Schiopu, A, Leosdottir, M

“…Abstract Background Cardiac rehabilitation (CR) is central in reducing morbidity and mortality after myocardial infarction (MI). However, the fulfillment of…”
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1070 Analysis of Lipid Composition in Human Cancer Cell Lines Before and After Treatment With Protolichesterinic Acid Isolated From Cetraria Islandica by Eiriksson, F, Sigurdsson, B, Omarsdottir, S, Ogmundsdottir, H, Thorsteinsdottir, M

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The effect of a single BRCA2 mutation on cancer in Iceland by Tulinius, H, Olafsdottir, G H, Sigvaldason, H, Arason, A, Barkardottir, R B, Egilsson, V, Ogmundsdottir, H M, Tryggvadottir, L, Gudlaugsdottir, S, Eyfjord, J E

“…Objective: To estimate the risk of malignant diseases in families of probands with the same mutation in the BRCA2 gene. Design: A cohort study using record…”
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Evidence for extrathymic T cell maturation after thymectomy in infancy by Torfadottir, H., Freysdottir, J., Skaftadottir, I., Haraldsson, A., Sigfusson, G., Ogmundsdottir, H. M.

“…Summary Our previous study showed that children who had been partially or completely thymectomized during heart surgery as infants had lower proportions and…”
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Longitudinal study of TP53 mutations in eight patients with potentially malignant oral mucosal disorders by Ögmundsdóttir, H. M., Hilmarsdóttir, H., Björnsson, J., Holbrook, W. P.

“…Objectives:  In a previous cross‐sectional study, the authors found a higher rate of TP53 mutation in oral lichen planus (OLP) than in hyperkeratosis. By…”
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