Search Results - "Ogloblina, Anna"

Toward G-Quadruplex-Based Anticancer Agents: Biophysical and Biological Studies of Novel AS1411 Derivatives by Ogloblina, Anna M, Iaccarino, Nunzia, Capasso, Domenica, Di Gaetano, Sonia, Garzarella, Emanuele U, Dolinnaya, Nina G, Yakubovskaya, Marianna G, Pagano, Bruno, Amato, Jussara, Randazzo, Antonio

“…Certain G-quadruplex forming guanine-rich oligonucleotides (GROs), including AS1411, are endowed with cancer-selective antiproliferative activity. They are…”
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Effects of G-Quadruplex-Binding Plant Secondary Metabolites on c-MYC Expression by Zenkov, Roman G., Kirsanov, Kirill I., Ogloblina, Anna M., Vlasova, Olga A., Naberezhnov, Denis S., Karpechenko, Natalia Y., Fetisov, Timur I., Lesovaya, Ekaterina A., Belitsky, Gennady A., Dolinnaya, Nina G., Yakubovskaya, Marianna G.

“…Guanine-rich DNA sequences tending to adopt noncanonical G-quadruplex (G4) structures are over-represented in promoter regions of oncogenes. Ligands…”
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Responses of DNA Mismatch Repair Proteins to a Stable G-Quadruplex Embedded into a DNA Duplex Structure by Pavlova, Anzhela V, Monakhova, Mayya V, Ogloblina, Anna M, Andreeva, Natalia A, Laptev, Gennady Yu, Polshakov, Vladimir I, Gromova, Elizaveta S, Zvereva, Maria I, Yakubovskaya, Marianna G, Oretskaya, Tatiana S, Kubareva, Elena A, Dolinnaya, Nina G

“…DNA mismatch repair (MMR) plays a crucial role in the maintenance of genomic stability. The main MMR protein, MutS, was recently shown to recognize the…”
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Transcription blockage by stable H-DNA analogs in vitro by Pandey, Shristi, Ogloblina, Anna M, Belotserkovskii, Boris P, Dolinnaya, Nina G, Yakubovskaya, Marianna G, Mirkin, Sergei M, Hanawalt, Philip C

“…DNA sequences that can form unusual secondary structures are implicated in regulating gene expression and causing genomic instability. H-palindromes are an…”
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Multi-targeted effects of G4-aptamers and their antiproliferative activity against cancer cells by Ogloblina, Anna M., Khristich, Alexandra N., Karpechenko, Natalia Y., Semina, Svetlana E., Belitsky, Gennady A., Dolinnaya, Nina G., Yakubovskaya, Marianna G.

“…We selected and investigated nine G-quadruplex (G4)-forming aptamers originally designed against different proteins involved in the regulation of cellular…”
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Tumor immunity portrait: An AI-driven molecular predictor combining tumor microenvironment and tumor mutational burden for immune checkpoint inhibitor response prediction by Shilo, Polina, Tarasov, Artem, Filatova, Anna, Danilov, Konstantin, Valiev, Ivan, Kotlov, Nikita, Brown, Jessica H., Ogloblina, Anna, Bagaev, Alexander, Fowler, Nathan

“…e14691 Background: Low response rates and toxicities from immune checkpoint inhibitors (ICI) highlight the need for improved ICI response prediction tools…”
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Aggregated analysis of 1,000 patients with cancer to assess the benefits of integrated whole exome and whole transcriptome sequencing by Chernyshov, Konstantin, Love, Anna, Senichkin, Viacheslav, Sagaradze, Georgy, Rumyantsev, Konstantin, Kushnarev, Vladimir, Postovalova, Ekaterina, Kotlov, Nikita, Ogloblina, Anna, Bagaev, Alexander, Fowler, Nathan

“…3076 Background: As the field of precision medicine rapidly expands, clinical oncologists are turning to integrated whole transcriptome (WTS) and whole exome…”
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RNA sequencing as a confirmatory assay and its impact on patient care in multiple cancer types by Kasi, Pashtoon Murtaza, Smirnova, Sofia, Nikulin, Vladislav, Brown, Jessica H., Almog, Nava, Ogloblina, Anna, Yam, Clinton, Peguero, Julio Antonio, Pandya, Devesh Mahesh, Kerr, Daniel, Fowler, Nathan

“…e15058 Background: Increasing evidence shows the ability of RNA sequencing (RNA-seq) to detect expression of multiple biomarkers with improved sensitivity and…”
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Integrated-omics of MRI-visible and -invisible prostate cancer identifies molecular correlations with clinical outcome by Kim, Eric, Miheecheva, Natalia, Ramachandran, Akshaya, Lyu, Yang, Galkin, Ilia, Svekolkin, Viktor, Postovalova, Ekaterina, Bagaev, Alexander, Nomie, Krystle, Ogloblina, Anna, Frenkel, Felix, Ataullakhanov, Ravshan, Hsieh, James J, Pachynski, Russell Kent

“…Abstract only e17506 Background: The inclusion of multiparametric MRI (mpMRI) to prostate cancer (PCa) diagnostics has increased the detection rate and has…”
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Integrated single-cell spatial multi-omics of intratumor heterogeneity in renal cell carcinoma by Hsieh, James J, Miheecheva, Natalia, Ramachandran, Akshaya, Lyu, Yang, Galkin, Ilia, Svekolkin, Viktor, Postovalova, Ekaterina, Bagaev, Alexander, Lozinsky, Yaroslav, Zyrin, Vladimir, Zaitsev, Aleksandr, Nuzhdina, Katerina, Nomie, Krystle, Ogloblina, Anna, Frenkel, Felix, Ataullakhanov, Ravshan

“…Abstract only e17106 Background: Clear cell renal cell carcinoma (ccRCC) exhibits conspicuous intratumor heterogeneity (ITH) - a driver of tumor evolution and…”
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