Search Results - "Ogishima, T"

Adrenal Nodularity and Somatic Mutations in Primary Aldosteronism: One Node Is the Culprit? by Dekkers, T, ter Meer, M, Lenders, J. W. M, Hermus, A. R. M, Schultze Kool, L, Langenhuijsen, J. F, Nishimoto, K, Ogishima, T, Mukai, K, Azizan, E. A. B, Tops, B, Deinum, J, Küsters, B

“…Context: Somatic mutations in genes that influence cell entry of calcium have been identified in aldosterone-producing adenomas (APAs) of adrenal cortex in…”
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Haeme-regulated Degradation of  -Aminolevulinate Synthase 1 in Rat Liver Mitochondria by Yoshino, K., Munakata, H., Kuge, O., Ito, A., Ogishima, T.

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A novel cell layer without corticosteroid-synthesizing enzymes in rat adrenal cortex: histochemical detection and possible physiological role by Mitani, F, Suzuki, H, Hata, J, Ogishima, T, Shimada, H, Ishimura, Y

“…A stratum of cells that did not contain both aldosterone synthase cytochrome P450 (cytochrome P450aldo) and cytochrome P45011 beta was found…”
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Isolation of Aldosterone Synthase Cytochrome P-450 from Zona Glomerulosa Mitochondria of Rat Adrenal Cortex by Ogishima, T, Mitani, F, Ishimura, Y

“…A cytochrome P-450 capable of producing aldosterone from 11-deoxycorticosterone was purified from the zona glomerulosa of rat adrenal cortex. The enzyme was…”
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Zone-specific expression of aldosterone synthase cytochrome P-450 and cytochrome P-45011 beta in rat adrenal cortex: histochemical basis for the functional zonation by Ogishima, T, Suzuki, H, Hata, J, Mitani, F, Ishimura, Y

“…Zonal distribution of aldosterone synthase cytochrome P-450 and cytochrome P-45011 beta in rat adrenocortex was investigated immunochemically using specific…”
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Aldosterone synthase cytochrome P-450 expressed in the adrenals of patients with primary aldosteronism by OGISHIMA, T, SHIBATA, H, SHIMADA, H, MITANI, F, SUZUKI, H, SARUTA, T, ISHIMURA, Y

“…A human cytochrome P-450 with aldosterone synthase activity was purified from the mitochondria of an aldosterone-producing adenoma. It was recognized by an…”
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A Proposed Common Structure of Substrates Bound to Mitochondrial Processing Peptidase by Kojima, Katsuhiko, Kitada, Sakae, Ogishima, Tadashi, Ito, Akio

“…Mitochondrial processing peptidase (MPP), a metalloendopeptidase consisting of α- and β-subunits, specifically cleaves off the N-terminal presequence of the…”
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Arginine residues in the extension peptide are required for cleavage of a precursor by mitochondrial processing peptidase. Demonstration using synthetic peptide as a substrate by Niidome, T, Kitada, S, Shimokata, K, Ogishima, T, Ito, A

“…Mitochondrial processing peptidase (MPP) specifically recognizes a large variety of mitochondrial precursor proteins and correctly cleaves off the extension…”
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Superoxide dismutase analog (Tempol: 4-hydroxy-2, 2, 6, 6-tetramethylpiperidine 1-oxyl) treatment restores erectile function in diabetes-induced impotence by Kawakami, T, Urakami, S, Hirata, H, Tanaka, Y, Nakajima, K, Enokida, H, Shiina, H, Ogishima, T, Tokizane, T, Kawamoto, K, Miura, K, Ishii, N, Dahiya, R

“…We hypothesized that the administration of the superoxide dismutase (SOD) mimetic Tempol (4-hydroxy-2, 2, 6, 6-tetramethylpiperidine 1-oxyl) may reverse…”
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Possible Participation of Outer Mitochondrial Membrane Cytochrome B 5 in Steroidogenesis in Zona Glomerulosa of Rat Adrenal Cortex by Mitani, Fumiko, Ogishima, T., Mukai, K., Hoshino, R., Watanabe, K., Suematsu, M.

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Purification and characterization of cholesterol 7 alpha-hydroxylase from rat liver microsomes by Ogishima, T, Deguchi, S, Okuda, K

“…Cholesterol 7 alpha-hydroxylase (cholesterol, NADPH: oxygen oxidoreductase, 7 alpha-hydroxylating, EC 1.14.13.17) was purified from liver microsomes of…”
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Substrate Recognition by Mitochondrial Processing Peptidase toward the Malate Dehydrogenase Precursor by Shimokata, Kunitoshi, Nishio, Takenori, Song, Myeong-Cheol, Kitada, Sakae, Ogishima, Tadashi, Ito, Akio

“…Mitochondrial processing peptidase (MPP) cleaves the extension peptides of precursor proteins newly imported into the mitochondria. Using synthetic…”
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Importance of Residues Carboxyl Terminal Relative to the Cleavage Site in Substrates of Mitochondrial Processing Peptidase for Their Specific Recognition and Cleavage by Song, Myeong-Cheol, Ogishima, Tadashi, Ito, Akio

“…We previously identified distal and proximal arginine residues in the N-terminal portion and an aromatic amino acid at position 1(P1' site3) relative to the…”
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Recognition of Mitochondrial Protein Precursor Lacking Arginine at Position —2 by Mitochondrial Processing Peptidase: Processing of Bovine Cytochrome P450(SCC) Precursor by Kojima, Katsuhiko, Yamasaki, Eiki, Kitada, Sakae, Ogishima, Tadashi, Ito, Akio

“…Mitochondrial processing peptidase (MPP) specifically cleaves off the N-terminal presequence of the mitochondrial protein precursor. Previous studies…”
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Analysis of Recognition Elements for Mitochondrial Processing Peptidase Using Artificial Amino Acids: Roles of the Intervening Portion and Proximal Arginine by Moriwaki, Kaori, Ogishima, Tadashi, Ito, Akio

“…We recently demonstrated, using synthetic peptides modeled on the extension peptide of malate dehydrogenase, that amino acid residues present at the proximal…”
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Role of Basic Amino Acids in the Cleavage of Synthetic Peptide Substrates by Mitochondrial Processing Peptidase by Song, Myeong-Cheol, Shimokata, Kunitoshi, Kitada, Sakae, Ogishima, Tadashi, Ito, Akio

“…Our recent experiments using model peptides of rat malate dehydrogenase (MDH) indicated that a proximal arginine and a distal basic amino acid are important…”
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Localization of P450aldo and P45011 beta in normal and regenerating rat adrenal cortex by Mitani, F, Ogishima, T, Miyamoto, H, Ishimura, Y

“…A novel layer of cells that do not contain both P450aldo and P45011 beta has been discovered between the zonae glomerulosa and fasciculata of the rat adrenal…”
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Competition between the krill fishery and penguins in the South Shetland Islands by ICHII, T, NAGANOBU, M, OGISHIMA, T

“…Among the South Shetland Islands, the potential competition for krill (Euphausia superba) between the Japanese fishery and krill-eating breeding penguins was…”
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Significance of steroidogenic enzymes in the pathogenesis of adrenal tumour by Shibata, H, Suzuki, H, Ogishima, T, Ishimura, Y, Saruta, T

“…We examined both activities and amounts of steroidogenic cytochrome P-450s at the posttranslational protein level and steroid contents in the adrenocortical…”
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Cytochrome P450 1B1 Is Overexpressed and Regulated by Hypomethylation in Prostate Cancer by TOKIZANE, Takashi, SHIINA, Hiroaki, NONOMURA, Norio, OKUYAMA, Akihiko, DAHIYA, Rajvir, IGAWA, Mikio, ENOKIDA, Hideki, URAKAMI, Shinji, KAWAKAMI, Toshifumi, OGISHIMA, Tatsuya, OKINO, Steven T, LI, Long-Cheng, TANAKA, Yuichiro

“…Purpose: Cytochrome P 450 1B1 ( CYP1B1 ), a dioxin inducible member of the CYP supergene family, is overexpressed in various human malignancies including…”
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