Search Results - "Ogidigo, Joyce Oloaigbe"
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Tumour Immunotherapy and Applications of Immunological Products: A Review of Literature
Published in Journal of immunology research (2024)“…Malignant tumors, characterized by uncontrolled cell proliferation, are a leading global health challenge, responsible for over 9.7 million deaths in 2022,…”
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Modulation of immunological responses by aqueous extract of Datura stramonium L. seeds on cyclophosphamide-induced immunosuppression in Wistar rats
Published in BMC immunology (19-10-2022)“…Datura stramonium L. (Solanaceae) is used traditionally in west Africa to treat asthma, epilepsy, rheumatoid arthritis, filariasis microbial infections and…”
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UPLC-PDA-ESI-QTOF-MS/MS fingerprint of purified flavonoid enriched fraction of Bryophyllum pinnatum; antioxidant properties, anticholinesterase activity and in silico studies
Published in Pharmaceutical biology (01-01-2021)“…Bryophyllum pinnatum (Lam.) Oken (Crassulaceae) is used traditionally to treat many ailments. This study characterizes the constituents of B. pinnatum…”
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High resolution UPLC-PDA-QTOF-ESI-MS/MS analysis of the flavonoid-rich fraction of Lasianthera africana leaves, and in vivo evaluation of its renal and cardiac function effects
Published in Heliyon (01-07-2020)“…Lasianthera africana P. Beauv. (Icacinaceae) is a traditional Nigerian medicinal plant used for treatment of ulcers, diarrhea, parasitic infections and…”
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Camptothecin shows better promise than Curcumin in the inhibition of the Human Telomerase: A computational study
Published in Heliyon (01-08-2021)“…The Human Telomerase enzyme has become a drug target in the treatment of cancers and age-related disorders. This study aims to identify potential natural…”
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Oral administration of Byrophyllum pinnatum flavonoid ameliorates cognitive impairment via modulating cortical neurochemicals and oxidative stress in aluminum chloride‐induced Alzheimer’s disease‐like condition in wistar rats: Nonhuman/Lead optimization studies
Published in Alzheimer's & dementia (01-12-2020)Get full text
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Oral administration of Byrophyllum pinnatum flavonoid ameliorates cognitive impairment via modulating cortical neurochemicals and oxidative stress in aluminum chloride‐induced Alzheimer’s disease‐like condition in wistar rats
Published in Alzheimer's & dementia (01-12-2020)“…Background Aluminum, a potent neurotoxicant is a major risk factor involved in the perturbation of neurochemicals leading to the development and progression of…”
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UNDERSTANDING THE CURRENT LOCATION DISPARITIES IN ADRD AND ITS DETERMINANTS IN NIGERIA
Published in Innovation in aging (21-12-2023)“…Alzheimer’s disease and related dementias (ADRD) is a growing health challenge in low- and middle-income countries, particularly in sub-Saharan Africa…”
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Natural phyto, compounds as possible noncovalent inhibitors against SARS-CoV2 protease: computational approach
Published in Journal of biomolecular structure & dynamics (24-03-2022)“…At present, there is no cure or vaccine for the devastating new highly infectious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has…”
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Neuroprotective effect of Bryophyllum pinnatum flavonoids against aluminum chloride-induced neurotoxicity in rats
Published in Toxicology mechanisms and methods (04-05-2022)“…Toxic metals such as aluminum accumulation in the brain have been associated with the pathophysiology of several neurodegenerative disorders. Bryophyllum…”
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Attenuating the Effects of Novel COVID-19 (SARS-CoV-2) Infection-Induced Cytokine Storm and the Implications
Published in Journal of inflammation research (01-01-2021)“…The COVID-19 pandemic constitutes an arduous global health challenge, and the increasing number of fatalities calls for the speedy pursuit of a remedy. This…”
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Prostate Specific Antigen, Antioxidant and Hematological Parameters in Prostatic Rats Fed Solanum macrocarpon L. Leaves
Published in Asian Journal of Biological Sciences (15-12-2014)Get full text
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