Search Results - "Oger, Romain"

The inhibitory receptor CD94/NKG2A on CD8+ tumor-infiltrating lymphocytes in colorectal cancer: a promising new druggable immune checkpoint in the context of HLAE/β2m overexpression by Eugène, Juliette, Jouand, Nicolas, Ducoin, Kathleen, Dansette, Delphine, Oger, Romain, Deleine, Cécile, Leveque, Edouard, Meurette, Guillaume, Podevin, Juliette, Matysiak, Tamara, Bennouna, Jaafar, Bezieau, Stéphane, Volteau, Christelle, Thomas, Wassila El Alami, Chetritt, Jerôme, Kerdraon, Olivier, Fourquier, Pierre, Thibaudeau, Emilie, Dumont, Frédéric, Mosnier, Jean-François, Toquet, Claire, Jarry, Anne, Gervois, Nadine, Bossard, Céline

“…We previously demonstrated that HLA-E/β2m overexpression by tumor cells in colorectal cancers is associated with an unfavorable prognosis. However, the…”
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A novel and efficient approach to high-throughput production of HLA-E/peptide monomer for T-cell epitope screening by Vaurs, Juliette, Douchin, Gaël, Echasserieau, Klara, Oger, Romain, Jouand, Nicolas, Fortun, Agnès, Hesnard, Leslie, Croyal, Mikaël, Pecorari, Frédéric, Gervois, Nadine, Bernardeau, Karine

“…Over the past two decades, there has been a great interest in the study of HLA-E-restricted αβ T cells during bacterial and viral infections, including…”
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Targeting NKG2A to boost anti-tumor CD8 T-cell responses in human colorectal cancer by Ducoin, Kathleen, Oger, Romain, Bilonda Mutala, Linda, Deleine, Cécile, Jouand, Nicolas, Desfrançois, Juliette, Podevin, Juliette, Duchalais, Emilie, Cruard, Jonathan, Benlalam, Houssem, Labarrière, Nathalie, Bossard, Céline, Jarry, Anne, Gervois-Segain, Nadine

“…Recently, the inhibitory CD94/NKG2A receptor has joined the group of immune checkpoints (ICs) and its expression has been documented in NK cells and CD8 + T…”
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HCMV triggers frequent and persistent UL40-specific unconventional HLA-E-restricted CD8 T-cell responses with potential autologous and allogeneic peptide recognition by Jouand, Nicolas, Bressollette-Bodin, Céline, Gérard, Nathalie, Giral, Magali, Guérif, Pierrick, Rodallec, Audrey, Oger, Romain, Parrot, Tiphaine, Allard, Mathilde, Cesbron-Gautier, Anne, Gervois, Nadine, Charreau, Béatrice

“…Immune response against human cytomegalovirus (HCMV) includes a set of persistent cytotoxic NK and CD8 T cells devoted to eliminate infected cells and to…”
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Transcriptomic features of tumour-infiltrating CD4lowCD8high double positive αβ T cells in melanoma by Parrot, Tiphaine, Oger, Romain, Allard, Mathilde, Desfrançois, Juliette, Raingeard de la Blétière, Diane, Coutolleau, Anne, Preisser, Laurence, Khammari, Amir, Dréno, Brigitte, Delneste, Yves, Guardiola, Philippe, Fradin, Delphine, Gervois, Nadine

“…Peripheral CD4 + CD8 + double positive (DP) T cells are a phenotypically and functionally heterogeneous population depending on their origin and pathologic…”
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Cross-presentation of synthetic long peptides by human dendritic cells: a process dependent on ERAD component p97/VCP but Not sec61 and/or Derlin-1 by Ménager, Jérémie, Ebstein, Frédéric, Oger, Romain, Hulin, Philippe, Nedellec, Steven, Duverger, Eric, Lehmann, Andrea, Kloetzel, Peter-Michael, Jotereau, Francine, Guilloux, Yannick

“…Antitumor vaccination using synthetic long peptides (SLP) is an additional therapeutic strategy currently under development. It aims to activate tumor-specific…”
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HLA-E-restricted cross-recognition of allogeneic endothelial cells by CMV-associated CD8 T cells: a potential risk factor following transplantation by Allard, Mathilde, Tonnerre, Pierre, Nedellec, Steven, Oger, Romain, Morice, Alexis, Guilloux, Yannick, Houssaint, Elisabeth, Charreau, Béatrice, Gervois, Nadine

“…Although association between CMV infection and allograft rejection is well admitted, the precise mechanisms involved remain uncertain. Here, we report the…”
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Serum soluble HLA-E in melanoma: a new potential immune-related marker in cancer by Allard, Mathilde, Oger, Romain, Vignard, Virginie, Percier, Jean-Michel, Fregni, Giulia, Périer, Aurélie, Caignard, Anne, Charreau, Béatrice, Bernardeau, Karine, Khammari, Amir, Dréno, Brigitte, Gervois, Nadine

“…Tumor-derived soluble factors, including soluble HLA molecules, can contribute to cancer immune escape and therefore impact on clinical course of malignant…”
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Broad Impairment of Natural Killer Cells from Operationally Tolerant Kidney Transplanted Patients by Dugast, Emilie, David, Gaëlle, Oger, Romain, Danger, Richard, Judor, Jean-Paul, Gagne, Katia, Chesneau, Mélanie, Degauque, Nicolas, Soulillou, Jean-Paul, Paul, Pascale, Picard, Christophe, Guerif, Pierrick, Conchon, Sophie, Giral, Magali, Gervois, Nadine, Retière, Christelle, Brouard, Sophie

“…The role of natural killer (NK) cells in organ transplantation is controversial. This study aims to decipher their role in kidney transplant tolerance in…”
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Corrigendum: Broad Impairment of Natural Killer Cells From Operationally Tolerant Kidney Transplanted Patients by Dugast, Emilie, David, Gaëlle, Oger, Romain, Danger, Richard, Judor, Jean-Paul, Gagne, Katia, Chesneau, Mélanie, Degauque, Nicolas, Soulillou, Jean-Paul, Paul, Pascale, Picard, Christophe, Guerif, Pierrick, Conchon, Sophie, Giral, Magali, Gervois, Nadine, Retière, Christelle, Brouard, Sophie

“…[This corrects the article on p. 1721 in vol. 8, PMID: 29312288.]…”
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Defining the Immune Checkpoint Landscape in Human Colorectal Cancer Highlights the Relevance of the TIGIT/CD155 Axis for Optimizing Immunotherapy by Ducoin, Kathleen, Bilonda-Mutala, Linda, Deleine, Cécile, Oger, Romain, Duchalais, Emilie, Jouand, Nicolas, Bossard, Céline, Jarry, Anne, Gervois-Segain, Nadine

“…While immune checkpoint (IC) therapies, particularly those targeting the PD-1/PD-L1 axis, have revolutionized the treatment of melanoma and several other…”
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High neutralizing potency of swine glyco‐humanized polyclonal antibodies against SARS‐CoV‐2 by Vanhove, Bernard, Duvaux, Odile, Rousse, Juliette, Royer, Pierre‐Joseph, Evanno, Gwénaëlle, Ciron, Carine, Lheriteau, Elsa, Vacher, Laurent, Gervois, Nadine, Oger, Romain, Jacques, Yannick, Conchon, Sophie, Salama, Apolline, Duchi, Roberto, Lagutina, Irina, Perota, Andrea, Delahaut, Philippe, Ledure, Matthieu, Paulus, Melody, So, Ray T., Mok, Chris Ka‐Pun, Bruzzone, Roberto, Bouillet, Marc, Brouard, Sophie, Cozzi, Emanuele, Galli, Cesare, Blanchard, Dominique, Bach, Jean‐Marie, Soulillou, Jean‐Paul

“…Heterologous polyclonal antibodies might represent an alternative to the use of convalescent plasma or monoclonal antibodies (mAbs) in coronavirus disease…”
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Abstract 4061: The inflammasome of tumor cells modulates the biology of tumor-infiltrating T lymphocytes in colorectal cancer by Bilonda, Linda, Dansette, Delphine, Deleine, Cecile, Oger, Romain, Jouand, Nicolas, Podevin, Juliette, Fourquier, Pierre, Thibaudeau, Emilie, Chetritt, Jerome, Mosnier, Jean-François, Bossard, Celine, Gervois, Nadine, Jarry, Anne

“…Abstract In colorectal cancer (CRC), little is known about mechanisms by which tumor cells can influence the biology of Tumor Infiltrating T lymphocytes (TILs)…”
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IL‐9 promotes the survival and function of human melanoma‐infiltrating CD4+CD8+ double‐positive T cells by Parrot, Tiphaine, Allard, Mathilde, Oger, Romain, Benlalam, Houssem, Raingeard de la Blétière, Diane, Coutolleau, Anne, Preisser, Laurence, Desfrançois, Juliette, Khammari, Amir, Dréno, Brigitte, Labarrière, Nathalie, Delneste, Yves, Guardiola, Philippe, Gervois, Nadine

“…We previously demonstrated an accumulation of tumor‐reactive CD4+CD8+ double positive (DP) T cells within melanoma‐infiltrating lymphocytes, supporting their…”
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Transcriptomic features of tumour-infiltrating CD4 low CD8 high double positive αβ T cells in melanoma by Parrot, Tiphaine, Oger, Romain, Allard, Mathilde, Desfrançois, Juliette, Raingeard de la Blétière, Diane, Coutolleau, Anne, Preisser, Laurence, Khammari, Amir, Dréno, Brigitte, Delneste, Yves, Guardiola, Philippe, Fradin, Delphine, Gervois, Nadine

“…Peripheral CD4 CD8 double positive (DP) T cells are a phenotypically and functionally heterogeneous population depending on their origin and pathologic…”
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Role of the inflammasome of tumor cells in modulating the biology of Tumor Infiltrating T lymphocytes (TILs) in colorectal cancer by Jarry, Anne, Ouairy, Adrien, Dansette, Delphine, Deleine, Cécile, Jouand, Nicolas, Oger, Romain, Podevin, Juliette, Fourquier, Pierre, Thibaudeau, Emilie, Chetritt, Jerome, Mosnier, Jean-François, Gervois, Nadine, Bossard, Celine

“…Abstract only e23087 Background: In colorectal cancer (CRC), little is known about mechanisms by which tumor cells can influence the phenotype and biology of…”
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Role of the inflammasome of tumor cells in modulating the biology of Tumor Infiltrating T lymphocytes (TILs) in colorectal cancer by Bossard, Celine, Dansette, Delphine, Ouairy, Adrien, Jouand, Nicolas, Oger, Romain, Bou-Hanna, Chantal, Laboisse, Christian, Mosnier, Jean-François, Gervois, Nadine, Jarry, Anne

“…Abstract only 640 Background: In colorectal cancer (CRC), little is known about mechanisms by which tumor cells can influence the phenotype and biology of…”
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The Caspase-1/IL-18 Axis of the Inflammasome in Tumor Cells: A Modulator of the Th1/Tc1 Response of Tumor-Infiltrating T Lymphocytes in Colorectal Cancer by Mutala, Linda Bilonda, Deleine, Cécile, Karakachoff, Matilde, Dansette, Delphine, Ducoin, Kathleen, Oger, Romain, Rousseau, Olivia, Podevin, Juliette, Duchalais, Emilie, Fourquier, Pierre, Thomas, Wassila El Alami, Gourraud, Pierre-Antoine, Bennouna, Jaafar, Brochier, Camille, Gervois, Nadine, Bossard, Céline, Jarry, Anne

“…In colorectal cancer (CRC), a high density of T lymphocytes represents a strong prognostic marker in subtypes of CRC. Optimized immunotherapy strategies to…”
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Soluble HLA-I/peptide monomers mediate antigen-specific CD8 T cell activation through passive peptide exchange with cell-bound HLA-I molecules by Allard, Mathilde, Oger, Romain, Benlalam, Houssem, Florenceau, Laetitia, Echasserieau, Klara, Bernardeau, Karine, Labarrière, Nathalie, Lang, François, Gervois, Nadine

“…Accumulating evidence that serum levels of soluble class I HLA molecules (sHLA-I) can, under various pathological conditions, correlate with disease stage…”
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IL-9 promotes the survival and function of human melanoma-infiltrating CD4 super(+)CD8 super(+) double-positive T cells by Parrot, Tiphaine, Allard, Mathilde, Oger, Romain, Benlalam, Houssem, Raingeard de la Bletiere, Diane, Coutolleau, Anne, Preisser, Laurence, Desfrancois, Juliette, Khammari, Amir, Dreno, Brigitte, Labarriere, Nathalie, Delneste, Yves, Guardiola, Philippe, Gervois, Nadine

“…We previously demonstrated an accumulation of tumor-reactive CD4 super(+)CD8 super(+) double positive (DP) T cells within melanoma-infiltrating lymphocytes,…”
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