Search Results - "Ogawa, Sosuke"
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Tannins from Acacia mearnsii De Wild. Bark: Tannin Determination and Biological Activities
Published in Molecules (Basel, Switzerland) (05-04-2018)“…The bark of De Wild. (black wattle) contains significant amounts of water-soluble components acalled "wattle tannin". Following the discovery of its strong…”
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Utilization of Flavonoid Compounds from Bark and Wood. III. Application in Health Foods
Published in Molecules (Basel, Switzerland) (26-07-2018)“…Dietary supplements ACAPOLIA and ACAPOLIA PLUS have been sold in Japan under the classification "Foods in General" for a number of years. In April 2015, the…”
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Analysis of anti-obesity and anti-diabetic effects of acacia bark-derived proanthocyanidins in type 2 diabetes model KKAy mice
Published in Journal of natural medicines (01-09-2021)“…The acacia bark extract derived from Acacia mearnsii De Wild is rich in proanthocyanidins, whose constituent units are robinetinidol, fisetinidol, catechin,…”
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Anti-Hypertensive Effects of Acacia Polyphenol in Spontaneously Hypertensive Rats
Published in International journal of molecular sciences (01-03-2018)“…We have previously demonstrated that acacia polyphenol (AP) exerts strong anti-obesity, anti-diabetic, and anti-atopic dermatitis effects. In the present…”
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Impact of Acacia bark extract tablets on the skin of healthy humans: a randomized, double-blind, placebo-controlled study
Published in Bioscience, biotechnology, and biochemistry (04-03-2019)“…This study investigated the effects of proanthocyanidins derived from Acacia (Acacia mearnsii) bark extract in healthy Japanese adult subjects experiencing…”
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Epigallocatechin gallate induces a hepatospecific decrease in the CYP3A expression level by altering intestinal flora
Published in European journal of pharmaceutical sciences (30-03-2017)“…In previous studies, we showed that a high-dose intake of green tea polyphenol (GP) induced a hepatospecific decrease in the expression and activity of the…”
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α-Amylase and Lipase Inhibitory Activity and Structural Characterization of Acacia Bark Proanthocyanidins
Published in Journal of natural products (Washington, D.C.) (25-02-2011)“…The bark extract of Acacia mearnsii showed strong lipase and α-amylase inhibition activities. Fractionation of the extract by column chromatography and…”
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Improvement of glucose metabolism and safety of acacia bark-derived proanthocyanidins in healthy Japanese adults: A Randomized, Double-blind, Placebo-controlled, Parallel-group Trial
Published in Functional foods in health and disease (03-09-2021)“…Objective: Acacia bark-derived proanthocyanidins exhibit antioxidant, anti-inflammatory, anti-diabetic, hypotensive effects, and improving skin condition, in…”
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Effects of the consumption of proanthocyanidins derived from acacia bark on blood pressure in healthy Japanese adults: A randomized, double-blind, placebo-controlled, parallel-group comparison study
Published in Functional foods in health and disease (16-07-2021)“…Objective: The aim of this study is to verify the effects of consuming proanthocyanidins derived from acacia bark on improving blood pressure and blood…”
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High-dose green tea polyphenol intake decreases CYP3A expression in a liver-specific manner with increases in blood substrate drug concentrations
Published in European journal of pharmaceutical sciences (30-06-2016)“…In recent years, the intake of functional foods containing high-doses of green tea polyphenols (GP) has been increasing. In this study, the long-term safety of…”
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Characterization of the α-Amylase Inhibitory Activity of Oligomeric Proanthocyanidins from Acacia mearnsii Bark Extract
Published in Natural product communications (01-12-2016)“…Acacia mearnsii (Fabaceae) contains acacia polyphenols, which are a complex mixture of proanthocyanidins that are mainly composed of 5-deoxycatechin units. In…”
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Effect of acacia polyphenol on glucose homeostasis in subjects with impaired glucose tolerance: A randomized multicenter feeding trial
Published in Experimental and therapeutic medicine (01-06-2013)“…Numerous in vitro and animal studies, as well as clinical trials have indicated that plant-derived polyphenols exert beneficial effects on glucose intolerance…”
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Ivermectin represses Wnt/β-catenin signaling by binding to TELO2, a regulator of phosphatidylinositol 3-kinase-related kinases
Published in iScience (18-03-2022)“…Ivermectin (IVM), an avermectin-derivative anthelmintic, specifically binds to glutamate-gated chloride ion channels (GluCls), causing paralysis in…”
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