Search Results - "Ogata, Souichi"

IgG1⁺ ovalbumin-specific B-cell transnuclear mice show class switch recombination in rare allelically included B cells by Dougan, Stephanie K, Ogata, Souichi, Hu, Chih-Chi Andrew, Grotenbreg, Gijsbert M, Guillen, Eduardo, Jaenisch, Rudolf, Ploegh, Hidde L

“…We used somatic cell nuclear transfer (SCNT) to generate a mouse from the nucleus of an IgG1 ⁺ ovalbumin-specific B cell. The resulting OBI mice show generally…”
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Unc5B interacts with FLRT3 and Rnd1 to modulate cell adhesion in Xenopus embryos by Karaulanov, Emil, Böttcher, Ralph T, Stannek, Peter, Wu, Wei, Rau, Marlene, Ogata, Souichi, Cho, Ken W Y, Niehrs, Christof

“…The FLRT family of transmembrane proteins has been implicated in the regulation of FGF signalling, neurite outgrowth, homotypic cell sorting and…”
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Abstract LB-329: Identification of alternative mechanisms of resistance to FGFR inhibitor treatment in FGFR1-amplified large cell compared to FGFR1-amplified small cell lung cancer models by Jovcheva, Eleonora, Ogata, Souichi, Ven, Kelly Van De, Paulussen, Caroline, Weyer, Inez Van de, Wolf, Hans D., Ceulemans, Hugo, McClue, Steve, Vialard, Jorge, Perera, Timothy

“…Abstract It is becoming increasingly clear that many solid tumors are not a homogeneous mass, but instead consist of highly heterogeneous microsystems…”
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Schnurri transcription factors from Drosophila and vertebrates can mediate Bmp signaling through a phylogenetically conserved mechanism by Yao, Li-Chin, Blitz, Ira L, Peiffer, Daniel A, Phin, Sopheap, Wang, Ying, Ogata, Souichi, Cho, Ken W Y, Arora, Kavita, Warrior, Rahul

“…Bone Morphogenetic Proteins (Bmps) are secreted growth factors that play crucial roles in animal development across the phylogenetic spectrum. Bmp signaling…”
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Phylogenetic footprinting and genome scanning identify vertebrate BMP response elements and new target genes by von Bubnoff, Andreas, Peiffer, Daniel A., Blitz, Ira L., Hayata, Tadayoshi, Ogata, Souichi, Zeng, Qiandong, Trunnell, Matthew, Cho, Ken W.Y.

“…The complex gene regulatory networks governed by growth factor signaling are still poorly understood. In order to accelerate the rate of progress in uncovering…”
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The role of a Williams-Beuren syndrome-associated helix-loop-helix domain-containing transcription factor in activin/nodal signaling by Ring, Colleen, Ogata, Souichi, Meek, Lauren, Song, Jihwan, Ohta, Tatsuru, Miyazono, Kohei, Cho, Ken W Y

“…We investigated the regulation of the activin/nodal-inducible distal element (DE) of the Xenopus goosecoid (gsc) promoter. On the basis of its interaction with…”
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Hyaluronan-enriched transfer medium (HETM) can improve the implantation rate in morphologically poor euploid blastocyst transfer by Nakagawa, Koji, Horikawa, Takashi, Orita, Yuji, Yamashiro, Emi, Watanabe, Hideaki, Shirai, Asako, Ogata, Souichi, Kataoka, Hisayo, Kuroda, Keiji, Takamizawa, Satoru, Sugiyama, Rikikazu

“…Purpose Hyaluronan-enriched transfer medium (HETM) could improve the clinical pregnancy rate (CPR) for patients with repeated implantation failures (RIF). In…”
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CD74-NRG1 fusions in lung adenocarcinoma by Fernandez-Cuesta, Lynnette, Plenker, Dennis, Osada, Hirotaka, Sun, Ruping, Menon, Roopika, Leenders, Frauke, Ortiz-Cuaran, Sandra, Peifer, Martin, Bos, Marc, Daßler, Juliane, Malchers, Florian, Schöttle, Jakob, Vogel, Wenzel, Dahmen, Ilona, Koker, Mirjam, Ullrich, Roland T, Wright, Gavin M, Russell, Prudence A, Wainer, Zoe, Solomon, Benjamin, Brambilla, Elisabeth, Nagy-Mignotte, Hélène, Moro-Sibilot, Denis, Brambilla, Christian G, Lantuejoul, Sylvie, Altmüller, Janine, Becker, Christian, Nürnberg, Peter, Heuckmann, Johannes M, Stoelben, Erich, Petersen, Iver, Clement, Joachim H, Sänger, Jörg, Muscarella, Lucia A, la Torre, Annamaria, Fazio, Vito M, Lahortiga, Idoya, Perera, Timothy, Ogata, Souichi, Parade, Marc, Brehmer, Dirk, Vingron, Martin, Heukamp, Lukas C, Buettner, Reinhard, Zander, Thomas, Wolf, Jürgen, Perner, Sven, Ansén, Sascha, Haas, Stefan A, Yatabe, Yasushi, Thomas, Roman K

“…We discovered a novel somatic gene fusion, CD74-NRG1, by transcriptome sequencing of 25 lung adenocarcinomas of never smokers. By screening 102 lung…”
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MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells by Beke, Lijs, Kig, Cenk, Linders, Joannes T M, Boens, Shannah, Boeckx, An, van Heerde, Erika, Parade, Marc, De Bondt, An, Van den Wyngaert, Ilse, Bashir, Tarig, Ogata, Souichi, Meerpoel, Lieven, Van Eynde, Aleyde, Johnson, Christopher N, Beullens, Monique, Brehmer, Dirk, Bollen, Mathieu

“…Maternal embryonic leucine zipper kinase (MELK), a serine/threonine protein kinase, has oncogenic properties and is overexpressed in many cancer cells. The…”
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Abstract 4791: OMO-1, a potent, highly selective, orally bioavailable, MET kinase inhibitor with a favorable preclinical toxicity profile, shows both monotherapy activity, against MET pathway-driven tumors, and EGFR TKI combination activity in acquired resistance models by Libouban, Marion, Jovcehva, Eleonora, Lange, Desiree De, Janssens, Boudewijn, Verhulst, Tinne, Ogata, Souichi, Wroblowski, Berthold, Mevellec, Laurence, Lu, Tianbao, Clack, Glen, Perera, Timothy

“…Abstract Activation of the MET/HGF pathway has been linked to tumor initiation, metastasis, angiogenesis and resistance to therapeutic agents. Here we present…”
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TGF-beta signaling-mediated morphogenesis: modulation of cell adhesion via cadherin endocytosis by Ogata, Souichi, Morokuma, Junji, Hayata, Tadayoshi, Kolle, Gabriel, Niehrs, Christof, Ueno, Naoto, Cho, Ken W Y

“…The molecular mechanisms governing the cell behaviors underlying morphogenesis remain a major focus of research in both developmental biology and cancer…”
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Transnuclear TRP1-specific CD8 T cells with high or low affinity TCRs show equivalent antitumor activity by Dougan, Stephanie K, Dougan, Michael, Kim, Jun, Turner, Jacob A, Ogata, Souichi, Cho, Hyun-Il, Jaenisch, Rudolf, Celis, Esteban, Ploegh, Hidde L

“…We have generated, via somatic cell nuclear transfer, two independent lines of transnuclear (TN) mice, using as nuclear donors CD8 T cells, sorted by tetramer…”
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Interaction between Wnt and TGF-β signalling pathways during formation of Spemann's organizer by Cho, Ken W. Y, Nishita, Michiru, Hashimoto, Minako K, Ogata, Souichi, Laurent, Micheline N, Ueno, Naoto, Shibuya, Hiroshi

“…Members of the Wnt and TGF-β superfamilies regulate both cell fate and proliferation during development and tissue maintenance. In the early amphibian embryo,…”
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Correction: MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells by Beke, Lijs, Kig, Cenk, Linders, Joannes T M, Boens, Shannah, Boeckx, An, van Heerde, Erika, Parade, Marc, De Bondt, An, Van den Wyngaert, Ilse, Bashir, Tarig, Ogata, Souichi, Meerpoel, Lieven, Van Eynde, Aleyde, Johnson, Christopher N, Beullens, Monique, Brehmer, Dirk, Bollen, Mathieu

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Dissection of Organizer and Animal Pole Explants from Xenopus laevis Embryos and Assembly of a Cell Adhesion Assay by Ogata, Souichi, Cho, Ken W.Y.

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A novel FLRT3 and Rnd1 pathway involved in TGF-β signaling-mediated cellular morphogenesis by Cho, Ken W., Ogata, Souichi, Morokuma, Junji, Hayata, Tadayoshi, Kolle, Gabriel, Niehrs, Christof, Ueno

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Dissection of organizer and animal pole explants from Xenopus laevis embryos and assembly of a cell adhesion assay by Ogata, Souichi, Cho, Ken W Y

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Plastic Embedding and Sectioning of Xenopus laevis Embryos by Ogata, Souichi, Kawauchi, Shimako, Calof, Anne, Cho, Ken W.Y.

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Activin/nodal signaling regulating cell fates and morphogenesis during Xenopus gastrulation by Ogata, Souichi

“…TGF-β growth factor superfamily members regulate major patterning and morphogenetic events during vertebrate embryogenesis. Activin, a member of the TGF-β…”
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Plastic embedding and sectioning of Xenopus laevis embryos by Ogata, Souichi, Kawauchi, Shimako, Calof, Anne, Cho, Ken W Y

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