Search Results - "Ogata, Hirotaka"

Cutting Edge: Cell Surface Expression and Lipopolysaccharide Signaling Via the Toll-Like Receptor 4-MD-2 Complex on Mouse Peritoneal Macrophages by Akashi, Sachiko, Shimazu, Rintaro, Ogata, Hirotaka, Nagai, Yoshinori, Takeda, Kiyoshi, Kimoto, Masao, Miyake, Kensuke

“…The human MD-2 molecule is associated with the extracellular domain of human Toll-like receptor 4 (TLR4) and greatly enhances its LPS signaling. The human…”
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The toll-like receptor protein RP105 regulates lipopolysaccharide signaling in B cells by Ogata, H, Su, I, Miyake, K, Nagai, Y, Akashi, S, Mecklenbräuker, I, Rajewsky, K, Kimoto, M, Tarakhovsky, A

“…The susceptibility to infections induced by Gram-negative bacteria is largely determined by innate immune responses to bacteria cell wall lipopolysaccharide…”
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Human MD-2 confers on mouse Toll-like receptor 4 species-specific lipopolysaccharide recognition by Akashi, Sachiko, Nagai, Yoshinori, Ogata, Hirotaka, Oikawa, Masato, Fukase, Koichi, Kusumoto, Shoichi, Kawasaki, Kiyoshi, Nishijima, Masahiro, Hayashi, Shinichiro, Kimoto, Masao, Miyake, Kensuke

“…Toll-like receptor 4 (TLR4) recognizes lipopolysaccharide (LPS). MD-2 is associated with TLR4 and imparts LPS responsiveness to it. Little is known, however,…”
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Facilitation of fatty acid uptake by CD36 in insulin-producing cells reduces fatty-acid-induced insulin secretion and glucose regulation of fatty acid oxidation by Wallin, Tina, Ma, Zuheng, Ogata, Hirotaka, Jørgensen, Ingrid Hals, Iezzi, Mariella, Wang, Haiyan, Wollheim, Claes B., Björklund, Anneli

“…Facilitation of fatty acid uptake in beta cells could potentially affect beta cell metabolism and secretory function; however such effects have not been…”
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Requirement for MD-1 in cell surface expression of RP105/CD180 and B-cell responsiveness to lipopolysaccharide by Nagai, Yoshinori, Shimazu, Rintaro, Ogata, Hirotaka, Akashi, Sachiko, Sudo, Katsuko, Yamasaki, Hidetoshi, Hayashi, Shin-Ichi, Iwakura, Yoichiro, Kimoto, Masao, Miyake, Kensuke

“…RP105 is a B-cell surface molecule that has been recently assigned as CD180. RP105 ligation with an antibody induces B-cell activation in humans and mice,…”
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Marked over expression of uncoupling protein-2 in beta cells exerts minor effects on mitochondrial metabolism by Hals, Ingrid K., Ogata, Hirotaka, Pettersen, Elin, Ma, Zuheng, Björklund, Anneli, Skorpen, Frank, Egeberg, Kjartan Wollo, Grill, Valdemar

“…► The impact of UCP-2 over expression on mitochondrial function is controversial. ► We tested mitochondrial functions at defined levels of overexpression. ► We…”
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Regulatory Roles for CD14 and Phosphatidylinositol in the Signaling via Toll-like Receptor 4-MD-2 by Akashi, Sachiko, Ogata, Hirotaka, Kirikae, Fumiko, Kirikae, Teruo, Kawasaki, Kiyoshi, Nishijima, Masahiro, Shimazu, Rintaro, Nagai, Yoshinori, Fukudome, Kenji, Kimoto, Masao, Miyake, Kensuke

“…The complex consisting of Toll-like receptor 4 (TLR4) and associated MD-2 signals the presence of lipopolysaccharide (LPS) when it is expressed in cell lines…”
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MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4 by Shimazu, R, Akashi, S, Ogata, H, Nagai, Y, Fukudome, K, Miyake, K, Kimoto, M

“…Toll-like receptor 4 (TLR4) is a mammalian homologue of Drosophila Toll, a leucine-rich repeat molecule that can trigger innate responses against pathogens…”
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Corrigendum to “Facilitation of fatty acid uptake by CD36 in insulin-producing cells reduces fatty-acid-induced insulin secretion and glucose regulation of fatty acid oxidation” [Biochim. Biophys. Acta 1801 (2010) 191–197] by Wallin, Tina, Ma, Zuheng, Ogata, Hirotaka, Jørgensen, Ingrid Hals, Iezzi, Mariella, Wang, Haiyan, Wollheim, Claes B., Björklund, Anneli

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Erratum to “Facilitation of fatty acid uptake by CD36 in insulin-producing cells reduces fatty-acid-induced insulin secretion and glucose regulation of fatty acid oxidation” [Biochim. Biophys. Acta 1801 (2010) 191–197] by Wallin, Tina, Ma, Zuheng, Ogata, Hirotaka, Jørgensen, Ingrid Hals, Iezzi, Mariella, Wang, Haiyan, Wollheim, Claes B., Björklund, Anneli

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Facilitation of fatty acid uptake by CD36 in insulin-producing cells reduces fatty-acid-induced insulin secretion and glucose regulation of fatty acid oxidation (vol 1801, pg 191, 2010) by Wallin, T, Ma, ZH, Ogata, H, Jorgensen, IH, Iezzi, M, Wang, HY, Wollheim, CB, Bjorklund, A

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Innate recognition of lipopolysaccharide by Toll-like receptor 4/MD-2 and RP105/MD-1 by Miyake, K, Ogata, H, Nagai, Y, Akashi, S, Kimoto, M

“…The Toll family of receptors has been implicated in innate recognition and subsequent activation of defense programs against pathogens such as bacteria and…”
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Mouse MD-1, a Molecule That Is Physically Associated with RP105 and Positively Regulates Its Expression by Miyake, Kensuke, Shimazu, Rintaro, Kondo, Jun, Niki, Tamotsu, Akashi, Sachiko, Ogata, Hirotaka, Yamashita, Yoshio, Miura, Yoshihiro, Kimoto, Masao

“…RP105 is a leucine-rich repeat molecule that is expressed on mouse B cells and transmits a growth-promoting signal. An anti-RP105 Ab precipitated additional…”
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RP105 Is Associated With MD-1 and Transmits an Activation Signal in Human B Cells by Miura, Yoshihiro, Shimazu, Rintaro, Miyake, Kensuke, Akashi, Sachiko, Ogata, Hirotaka, Yamashita, Yoshio, Narisawa, Yutaka, Kimoto, Masao

“…RP105 was originally discovered as a mouse B-cell surface molecule that transmits an activation signal. The signal leads to resistance against…”
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Facilitation of fatty acid uptake by CD36 in insulin-producing cells reduces fatty-acid-induced insulin secretion and glucose regulation of fatty acid oxidation (vol 1801, pg 191, 2010) by Wallin, T, Ma, ZH, Ogata, H, Jorgensen, IH, Iezzi, M, Wang, HY, Wollheim, CB, Bjorklund, A

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RP105 is associated with MD-1 and transmits an activation signal in human B cells by MIURA, Y, SHIMAZU, R, MIYAKE, K, AKASHI, S, OGATA, H, YAMASHITA, Y, NARISAWA, Y, KIMOTO, M

“…RP105 was originally discovered as a mouse B-cell surface molecule that transmits an activation signal. The signal leads to resistance against…”
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