Search Results - "Ogasawara, Saori"

Inhibitory effects of xanthine oxidase inhibitor, topiroxostat, on development of neuropathy in db/db mice by Takahashi, Kazuhisa, Mizukami, Hiroki, Osonoi, Sho, Ogasawara, Saori, Hara, Yutaro, Kudoh, Kazuhiro, Takeuchi, Yuki, Sasaki, Takanori, Daimon, Makoto, Yagihashi, Soroku

“…Inflammation and oxidative stress contribute to the pathophysiology of diabetic neuropathy. According to recent evidence, the modulation of macrophage…”
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The diversity and abundance of gut microbiota are associated with the pain sensation threshold in the Japanese population by Takeuchi, Yuki, Mizukami, Hiroki, Kudoh, Kazuhiro, Osonoi, Sho, Sasaki, Takanori, Kushibiki, Hanae, Ogasawara, Saori, Hara, Yutaro, Igawa, Akiko, Pan, Xuekai, Yamada, Takahiro, Yamazaki, Keisuke, Mikami, Tatsuya, Daimon, Makoto, Yagihashi, Soroku, Hakamada, Kenichi, Nakaji, Shigeyuki

“…Small fibre neuropathy (SFN) is an initial pathology of diabetic polyneuropathy (DPN). Serum lipopolysaccharide binding protein levels are positively…”
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Rice amino acid transporter‐like 6 (OsATL6) is involved in amino acid homeostasis by modulating the vacuolar storage of glutamine in roots by Ogasawara, Saori, Ezaki, Masataka, Ishida, Ryusuke, Sueyoshi, Kuni, Saito, Shunya, Hiradate, Yuki, Kudo, Toru, Obara, Mitsuhiro, Kojima, Soichi, Uozumi, Nobuyuki, Tanemura, Kentaro, Hayakawa, Toshihiko

“…Summary Glutamine is a product of ammonium (NH4+) assimilation catalyzed by glutamine synthetase (GS) and glutamate synthase (GOGAT). The growth of…”
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Neuropathy in the spontaneously hypertensive rat: An electrophysiological and histological study by Nukada, Hitoshi, Baba, Masayuki, Ogasawara, Saori, McMorran, Denise, Yagihashi, Soroku

“…ABSTRACT Introduction: Hypertension is identified as a risk factor for development of polyneuropathy. In this study we examined nerve conduction and…”
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A spontaneously immortalized Schwann cell line from aldose reductase‐deficient mice as a useful tool for studying polyol pathway and aldehyde metabolism by Niimi, Naoko, Yako, Hideji, Takaku, Shizuka, Kato, Hiroshi, Matsumoto, Takafumi, Nishito, Yasumasa, Watabe, Kazuhiko, Ogasawara, Saori, Mizukami, Hiroki, Yagihashi, Soroku, Chung, Sookja K., Sango, Kazunori

“…The increased glucose flux into the polyol pathway via aldose reductase (AR) is recognized as a major contributing factor for the pathogenesis of diabetic…”
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Increased Oxidative Stress Underlies Abnormal Pain Threshold in a Normoglycemic Japanese Population by Osonoi, Sho, Mizukami, Hiroki, Itabashi, Chieko, Wada, Kanichiro, Kudoh, Kazuhiro, Igawa, Akiko, Ogasawara, Saori, Ishibashi, Yasuyuki, Daimon, Makoto, Yagihashi, Soroku, Nakaji, Shigeyuki

“…Normal-high HbA1c levels are a risk factor for attenuated pain sensation in normoglycemic subjects. It is unclear, however, what mechanisms underlie the…”
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RAGE activation in macrophages and development of experimental diabetic polyneuropathy by Osonoi, Sho, Mizukami, Hiroki, Takeuchi, Yuki, Sugawa, Hikari, Ogasawara, Saori, Takaku, Shizuka, Sasaki, Takanori, Kudoh, Kazuhiro, Ito, Koichi, Sango, Kazunori, Nagai, Ryoji, Yamamoto, Yasuhiko, Daimon, Makoto, Yamamoto, Hiroshi, Yagihashi, Soroku

“…It is suggested that activation of receptor for advanced glycation end products (RAGE) induces proinflammatory response in diabetic nerve tissues. Macrophage…”
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Role of glucosamine in development of diabetic neuropathy independent of the aldose reductase pathway by Mizukami, Hiroki, Osonoi, Sho, Takaku, Shizuka, Yamagishi, Shin-Ichiro, Ogasawara, Saori, Sango, Kazunori, Chung, Sookja, Yagihashi, Soroku

“…Abstract Long-term metabolic aberrations contribute to the development of diabetic neuropathy but the precise mechanism or mechanisms remains elusive. We have…”
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Methylcobalamin effects on diabetic neuropathy and nerve protein kinase C in rats by Mizukami, Hiroki, Ogasawara, Saori, Yamagishi, Shin-Ichiro, Takahashi, Kazunori, Yagihashi, Soroku

“…Eur J Clin Invest 2011; 41 (4): 442–450 Background  Methyl‐base‐attached cobalamin (Methycobalamin) (MC) has a special affinity for nerve tissues to promote…”
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Normal High HbA1c a Risk Factor for Abnormal Pain Threshold in the Japanese Population by Itabashi, Chieko, Mizukami, Hiroki, Osonoi, Sho, Takahashi, Kazuhisa, Kudo, Kazuhiro, Wada, Kanichiro, Inaba, Wataru, Danyang, Guo, Uchida, Chiaki, Umetsu, Satoko, Igawa, Akiko, Ogasawara, Saori, Ryuzaki, Masaki, Komeda, Kouji, Ishibashi, Yasuyuki, Yagihashi, Soroku, Nakaji, Shigeyuki

“…Small fiber dysfunction is common in subjects with diabetic polyneuropathy (DPN). It is unsettled, however, whether marginal glucose intolerance is implicated…”
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Lipopolysaccharide-binding protein is a distinctive biomarker of abnormal pain threshold in the general Japanese population by Kudoh, Kazuhiro, Mizukami, Hiroki, Itabashi, Chieko, Fuke, Nobuo, Osonoi, Sho, Takeuchi, Yuki, Wada, Kanichiro, Igawa, Akiko, Ogasawara, Saori, Ishibashi, Yasuyuki, Hakamada, Kenichi, Yagihashi, Soroku, Nakaji, Shigeyuki

“…IntroductionSmall fiber neuropathy (SFN) is an early manifestation in diabetic polyneuropathy (DPN); however, the mechanisms are not fully understood. In…”
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Increased susceptibility to ischemia and macrophage activation in STZ-diabetic rat nerve by Nukada, Hitoshi, McMorran, P. Denise, Baba, Masayuki, Ogasawara, Saori, Yagihashi, Soroku

“…Abstract Ischemic vulnerability in diabetic nerve plays a paramount role in the development of diabetic neuropathy, yet little is known of the underlying…”
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Corrigendum: Normal High HbA1c a Risk Factor for Abnormal Pain Threshold in the Japanese Population by Itabashi, Chieko, Mizukami, Hiroki, Osonoi, Sho, Takahashi, Kazuhisa, Kudo, Kazuhiro, Wada, Kanichiro, Inaba, Wataru, Danyang, Guo, Uchida, Chiaki, Umetsu, Satoko, Igawa, Akiko, Ogasawara, Saori, Ryuzaki, Masaki, Komeda, Kouji, Ishibashi, Yasuyuki, Yagihashi, Soroku, Nakaji, Shigeyuki

“…[This corrects the article DOI: 10.3389/fendo.2019.00651.]…”
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role of the polyol pathway in acute kidney injury caused by hindlimb ischaemia in mice by Yagihashi, Soroku, Mizukami, Hiroki, Ogasawara, Saori, Yamagishi, Shin-Ichiro, Nukada, Hitoshi, Kato, Noriaki, Hibi, Chihiro, Chung, Sookja, Chung, Stephen

“…The polyol pathway, a collateral glycolytic process, previously considered to be active in high glucose milieu, has recently been proposed to play a crucial…”
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Hypertension is associated with the reduction in epidermal small fibres independently of sural nerve inflammation in type 2 diabetic subjects by Wang, Zhenchao, Kushibiki, Hanae, Tarusawa, Takefusa, Osonoi, Sho, Ogasawara, Saori, Miura, Chinatsu, Sasaki, Takanori, Ryuzaki, Masaki, Yagihashi, Soroku, Mizukami, Hiroki

“…Diabetic polyneuropathy (DPN) is a multifactorial disease associated not only with hyperglycaemia but also with circulatory disturbances such as hypertension…”
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"q-NAVI"; a case of market-based implementation of structural health monitoring in Japan by Kanda, Katsuhisa, Nakashima, Masayoshi, Suzuki, Yoshitaka, Ogasawara, Saori

“…In Japan, structural health monitoring (SHM) of building structures began in the 1950s, but, until recently, its widespread use was not realized. A new trend…”
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80-OR: Proinflammatory Macrophage Impairs Retrograde Axonal Transport via Inflammation and Insulin Resistance in Sensory Neurons by OSONOI, SHO, MIZUKAMI, HIROKI, OGASAWARA, SAORI, KUDOH, KAZUHIRO, DAIMON, MAKOTO, YAGIHASHI, SOROKU

“…Inflammation, insulin resistance (IR) , and deficit of retrograde axonal transport (RAT) are implicated in the pathogenesis of diabetic polyneuropathy (DPN) …”
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466-P: Changes in Oral and Intestinal Bacterial Flora Associated with Pain Thresholds by KUDOH, KAZUHIRO, TAKEUCHI, YUKI, OSONOI, SHO, SASAKI, TAKANORI, OGASAWARA, SAORI, YAGIHASHI, SOROKU, MIZUKAMI, HIROKI

“…Small fiber neuropathy (SFN) manifests from the early stages of diabetic polyneuropathy. Changes in the oral and intestinal bacterial flora are known to be…”
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Beneficial effects of combination therapy of canagliflozin and teneligliptin on diabetic polyneuropathy and β-cell volume density in spontaneously type 2 diabetic Goto-Kakizaki rats by Guo, Danyang, Mizukami, Hiroki, Osonoi, Sho, Takahashi, Kazuhisa, Ogasawara, Saori, Kudo, Kazuhiro, Sasaki, Takanori, Yagihashi, Soroku

“…Parasympathetic nerve (PN) signaling plays a crucial role in the maintenance of pancreatic β-cell volume density (Vβ). PN may be pathologically affected in…”
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Moderate cryptoxanthin intake correlates with maintenance of a proper PINT index in a general Japanese population by Ryuzaki, Masaki, Mizukami, Hiroki, Takeuchi, Yuki, Osonoi, Sho, Sasaki, Takanori, Wang, Zhenchao, Kushibiki, Hanae, Yamada, Takahiro, Yamazaki, Keisuke, Ogasawara, Saori, Tarusawa, Takefusa, Mikami, Tatsuya, Hakamada, Kenichi, Nakaji, Shigeyuki

“…Small fibre neuropathy (SFN) is an early manifestation of diabetic polyneuropathy. Although oxidative stress, inflammation and change of intestinal bacterial…”
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