Search Results - "Ofenbauer, Andreas"
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FACT Sets a Barrier for Cell Fate Reprogramming in Caenorhabditis elegans and Human Cells
Published in Developmental cell (10-09-2018)“…The chromatin regulator FACT (facilitates chromatin transcription) is essential for ensuring stable gene expression by promoting transcription. In a genetic…”
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A novel, low-volume method for organ culture of embryonic kidneys that allows development of cortico-medullary anatomical organization
Published in PloS one (10-05-2010)“…Here, we present a novel method for culturing kidneys in low volumes of medium that offers more organotypic development compared to conventional methods. Organ…”
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Strategies for in vivo reprogramming
Published in Current opinion in cell biology (01-12-2019)“…Reprogramming has the potential to provide specific cell types for regenerative medicine applications aiming at replacing tissues that have been lost or…”
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The CONJUDOR pipeline for multiplexed knockdown of gene pairs identifies RBBP-5 as a germ cell reprogramming barrier in C. elegans
Published in Nucleic acids research (26-02-2021)“…Abstract Multiple gene activities control complex biological processes such as cell fate specification during development and cellular reprogramming…”
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The C. elegans pseudogene sspt-16 (F55A3.7) is required to safeguard germ cells against reprogramming
Published in microPublication biology (18-05-2021)“…We recently identified FAcilitates Chromatin Transcription (FACT) as a reprogramming barrier of transcription factor (TF) mediated conversion of germ cells…”
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MRG-1/MRG15 Is a Barrier for Germ Cell to Neuron Reprogramming in Caenorhabditis elegans
Published in Genetics (Austin) (01-01-2019)“…Chromatin regulators play important roles in the safeguarding of cell identities by opposing the induction of ectopic cell fates and, thereby, preventing…”
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Characterization of the KASH Domain Gene unc-83 and the Pseudogene F55A3.7
Published 01-01-2019“…Mein Ziel war es, genetische Faktoren in C. elegans zu identifizieren, die eine Rolle bei induzierter Transdifferenzierung durch Missexpression des…”
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Dissertation -
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ECM modulated early kidney development in embryonic organ culture
Published in Biomaterials (01-09-2013)“…Abstract The use of exogenous signals is gaining importance in renal regenerative therapies. We wanted to explore the role of extracellular matrix (ECM)…”
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Dewaxed ECM: A simple method for analyzing cell behaviour on decellularized extracellular matrices
Published in Journal of tissue engineering and regenerative medicine (01-09-2015)“…Decellularization techniques have been used on a wide variety of tissues to create cell‐seedable scaffolds for tissue engineering. Finding a suitable…”
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