Search Results - "Oettinghaus, Björn"

Neuronal Mitochondrial Dysfunction Activates the Integrated Stress Response to Induce Fibroblast Growth Factor 21 by Restelli, Lisa Michelle, Oettinghaus, Björn, Halliday, Mark, Agca, Cavit, Licci, Maria, Sironi, Lara, Savoia, Claudia, Hench, Jürgen, Tolnay, Markus, Neutzner, Albert, Schmidt, Alexander, Eckert, Anne, Mallucci, Giovanna, Scorrano, Luca, Frank, Stephan

“…Stress adaptation is essential for neuronal health. While the fundamental role of mitochondria in neuronal development has been demonstrated, it is still not…”
Get full text

Less than perfect divorces: dysregulated mitochondrial fission and neurodegeneration by Oettinghaus, Björn, Licci, Maria, Scorrano, Luca, Frank, Stephan

“…Research efforts during the last decade have deciphered the basic molecular mechanisms governing mitochondrial fusion and fission. We now know that in…”
Get full text

DRP1-dependent apoptotic mitochondrial fission occurs independently of BAX, BAK and APAF1 to amplify cell death by BID and oxidative stress by Oettinghaus, Björn, D'Alonzo, Donato, Barbieri, Elisa, Restelli, Lisa Michelle, Savoia, Claudia, Licci, Maria, Tolnay, Markus, Frank, Stephan, Scorrano, Luca

“…During apoptosis mitochondria undergo cristae remodeling and fragmentation, but how the latter relates to outer membrane permeabilization and downstream…”
Get full text

Mutant MRPS5 affects mitoribosomal accuracy and confers stress‐related behavioral alterations by Akbergenov, Rashid, Duscha, Stefan, Fritz, Ann‐Kristina, Juskeviciene, Reda, Oishi, Naoki, Schmitt, Karen, Shcherbakov, Dimitri, Teo, Youjin, Boukari, Heithem, Freihofer, Pietro, Isnard‐Petit, Patricia, Oettinghaus, Björn, Frank, Stephan, Thiam, Kader, Rehrauer, Hubert, Westhof, Eric, Schacht, Jochen, Eckert, Anne, Wolfer, David, Böttger, Erik C

“…The 1555 A to G substitution in mitochondrial 12S A‐site rRNA is associated with maternally transmitted deafness of variable penetrance in the absence of…”
Get full text

Silencing of the ER and Integrative Stress Responses in the Liver of Mice with Error-Prone Translation by Moore, James, Osinnii, Ivan, Grimm, Amandine, Oettinghaus, Björn, Eckert, Anne, Frank, Stephan, Böttger, Erik C

“…Translational errors frequently arise during protein synthesis, producing misfolded and dysfunctional proteins. Chronic stress resulting from translation…”
Get full text

Phylogenetic Sequence Variations in Bacterial rRNA Affect Species-Specific Susceptibility to Drugs Targeting Protein Synthesis by Akshay, Subramanian, Bertea, Mihai, Hobbie, Sven N, Oettinghaus, Björn, Shcherbakov, Dimitri, Böttger, Erik C, Akbergenov, Rashid

“…Antibiotics targeting the bacterial ribosome typically bind to highly conserved rRNA regions with only minor phylogenetic sequence variations. It is unclear…”
Get full text

Apaf1 plays a pro-survival role by regulating centrosome morphology and function by Ferraro, Elisabetta, Pesaresi, Maria Grazia, De Zio, Daniela, Cencioni, Maria Teresa, Gortat, Anne, Cozzolino, Mauro, Berghella, Libera, Salvatore, Anna Maria, Oettinghaus, Bjorn, Scorrano, Luca, Pérez-Payà, Enrique, Cecconi, Francesco

“…The apoptotic protease activating factor 1 (Apaf1) is the main component of the apoptosome, and a crucial factor in the mitochondria-dependent death pathway…”
Get full text

Mutant MRPS 5 affects mitoribosomal accuracy and confers stress‐related behavioral alterations by Akbergenov, Rashid, Duscha, Stefan, Fritz, Ann‐Kristina, Juskeviciene, Reda, Oishi, Naoki, Schmitt, Karen, Shcherbakov, Dimitri, Teo, Youjin, Boukari, Heithem, Freihofer, Pietro, Isnard‐Petit, Patricia, Oettinghaus, Björn, Frank, Stephan, Thiam, Kader, Rehrauer, Hubert, Westhof, Eric, Schacht, Jochen, Eckert, Anne, Wolfer, David, Böttger, Erik C

Get full text

Tonight, the same old, deadly programme: BH3-only proteins, mitochondria and yeast by Oettinghaus, Bjorn, Frank, Stephan, Scorrano, Luca

“…EMBO J 30 14, 2779-2792 (2011); published online 14 June 2011…”
Get full text

Tonight, the same old, deadly programme: BH3-only proteins, mitochondria and yeast: Tonight, the same old, deadly programme by Oettinghaus, Bjorn, Frank, Stephan, Scorrano, Luca

Get full text