Search Results - "Oertlin, C"

Characterization of clonal evolution in pediatric lymphoma using single‐cell transcriptomics by D'aulerio, R., Yong, T., Oertlin, C., Record, J. A., Kwiecinska, A., Baecklund, F., Westerberg, L. S.

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Generally applicable transcriptome-wide analysis of translation using anota2seq by Oertlin, Christian, Lorent, Julie, Murie, Carl, Furic, Luc, Topisirovic, Ivan, Larsson, Ola

“…Abstract mRNA translation plays an evolutionarily conserved role in homeostasis and when dysregulated contributes to various disorders including metabolic and…”
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17th International Conference on Malignant Lymphoma, Palazzo dei Congressi, Lugano, Switzerland, 13 - 17 June, 2023 by D'aulerio, R, Yong, T, Oertlin, C, Record, J A, Kwiecinska, A, Baecklund, F, Westerberg, L S

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Enhanced translation expands the endo-lysosome size and promotes antigen presentation during phagocyte activation by Hipolito, Victoria E B, Diaz, Jacqueline A, Tandoc, Kristofferson V, Oertlin, Christian, Ristau, Johannes, Chauhan, Neha, Saric, Amra, Mclaughlan, Shannon, Larsson, Ola, Topisirovic, Ivan, Botelho, Roberto J

“…The mechanisms that govern organelle adaptation and remodelling remain poorly defined. The endo-lysosomal system degrades cargo from various routes, including…”
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eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma by Chan, Karina, Robert, Francis, Oertlin, Christian, Kapeller-Libermann, Dana, Avizonis, Daina, Gutierrez, Johana, Handly-Santana, Abram, Doubrovin, Mikhail, Park, Julia, Schoepfer, Christina, Da Silva, Brandon, Yao, Melissa, Gorton, Faith, Shi, Junwei, Thomas, Craig J., Brown, Lauren E., Porco, John A., Pollak, Michael, Larsson, Ola, Pelletier, Jerry, Chio, Iok In Christine

“…Pancreatic ductal adenocarcinoma (PDA) is a lethal malignancy with limited treatment options. Although metabolic reprogramming is a hallmark of many cancers,…”
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Adaptation to mitochondrial stress requires CHOP-directed tuning of ISR by Kaspar, Sophie, Oertlin, Christian, Szczepanowska, Karolina, Kukat, Alexandra, Senft, Katharina, Lucas, Christina, Brodesser, Susanne, Hatzoglou, Maria, Larsson, Ola, Topisirovic, Ivan, Trifunovic, Aleksandra

“…In response to disturbed mitochondrial gene expression and protein synthesis, an adaptive transcriptional response sharing a signature of the integrated stress…”
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Polysome-profiling in small tissue samples by Liang, Shuo, Bellato, Hermano Martins, Lorent, Julie, Lupinacci, Fernanda C S, Oertlin, Christian, van Hoef, Vincent, Andrade, Victor P, Roffé, Martín, Masvidal, Laia, Hajj, Glaucia N M, Larsson, Ola

“…Abstract Polysome-profiling is commonly used to study translatomes and applies laborious extraction of efficiently translated mRNA (associated with >3…”
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Anota2seq Analysis for Transcriptome-Wide Studies of mRNA Translation by Oertlin, Christian, Watt, Kathleen, Ristau, Johannes, Larsson, Ola

“…mRNA translation plays a critical role in determining proteome composition. In health, regulation of mRNA translation facilitates rapid gene expression…”
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Polysome Fractionation for Transcriptome-Wide Studies of mRNA Translation by Ristau, Johannes, Watt, Kathleen, Oertlin, Christian, Larsson, Ola

“…Protein synthesis and degradation determine the relationship between mRNA and corresponding protein amounts. This relationship can change in a dynamic and…”
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Next generation of astronauts or ESA astronaut 2.0 concept and spotlight on immunity by Jacob, Pauline, Oertlin, Christian, Baselet, Bjorn, Westerberg, Lisa S., Frippiat, Jean-Pol, Baatout, Sarah

“…Although we have sent humans into space for more than 50 years, crucial questions regarding immune response in space conditions remain unanswered. There are…”
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Targeting redox dependencies in pancreatic cancer by Chio, IIC, Oertlin, C, Robert, F, Chan, K, Liberm, DK, Santana, A, Park, Y, Larsson, O, Pelletier, J, Tuveson, D

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Transcriptome-wide polysome profiling of glioblastomas identifies molecular subgroups with impact in survival and treatment by Hajj, GN, Lupinacci, FC, Roffe, M, Bellaro, HM, Santos, TG, Andrade, VP, Sanematsu, P, Reis, RM, Oertlin, C, Sanz, LM, Martins, VR, Larsson, O

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Exposure of volunteers to microgravity by dry immersion bed over 21 days results in gene expression changes and adaptation of T cells by Gallardo-Dodd, Carlos J., Oertlin, Christian, Record, Julien, Galvani, Rômulo G., Sommerauer, Christian, Kuznetsov, Nikolai V., Doukoumopoulos, Evangelos, Ali, Liaqat, Oliveira, Mariana M. S., Seitz, Christina, Percipalle, Mathias, Nikić, Tijana, Sadova, Anastasia A., Shulgina, Sofia M., Shmarov, Vjacheslav A., Kutko, Olga V., Vlasova, Daria D., Orlova, Kseniya D., Rykova, Marina P., Andersson, John, Percipalle, Piergiorgio, Kutter, Claudia, Ponomarev, Sergey A., Westerberg, Lisa S.

“…The next steps of deep space exploration are manned missions to Moon and Mars. For safe space missions for crew members, it is important to understand the…”
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